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公开(公告)号：US12054745B2
公开(公告)日：2024-08-06
申请号：US17670124
申请日：2022-02-11
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey Robert Millman , Michael Saris Segel , Mads Gurtler
CPC分类号： C12N5/0678 , A61K35/39 , A61P3/10 , A61P5/48 , A61P5/50 , C12N5/0606 , C12N5/0676 , C12N5/0696 , C12N2501/11 , C12N2501/117 , C12N2501/15 , C12N2501/16 , C12N2501/375 , C12N2501/385 , C12N2501/395 , C12N2501/40 , C12N2501/41 , C12N2501/727 , C12N2501/998 , C12N2501/999 , C12N2506/02 , C12N2506/03 , C12N2506/22 , C12N2506/45
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US11078463B2
公开(公告)日：2021-08-03
申请号：US16934333
申请日：2020-07-21
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/0735 , C12N5/074
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US12049646B2
公开(公告)日：2024-07-30
申请号：US18395362
申请日：2023-12-22
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey Robert Millman , Michael Saris Segel , Mads Gurtler
CPC分类号： C12N5/0678 , A61K35/39 , A61P3/10 , A61P5/48 , A61P5/50 , C12N5/0606 , C12N5/0676 , C12N5/0696 , C12N2501/11 , C12N2501/117 , C12N2501/15 , C12N2501/16 , C12N2501/375 , C12N2501/385 , C12N2501/395 , C12N2501/40 , C12N2501/41 , C12N2501/727 , C12N2501/998 , C12N2501/999 , C12N2506/02 , C12N2506/03 , C12N2506/22 , C12N2506/45
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US11162078B2
公开(公告)日：2021-11-02
申请号：US16934412
申请日：2020-07-21
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/0735 , C12N5/074
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US20190040362A1
公开(公告)日：2019-02-07
申请号：US16042917
申请日：2018-07-23
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/074 , C12N5/0735
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US10030229B2
公开(公告)日：2018-07-24
申请号：US14684101
申请日：2015-04-10
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/073 , C12N5/074 , C12N5/0735
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US11827905B2
公开(公告)日：2023-11-28
申请号：US17978936
申请日：2022-11-01
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey Robert Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/0735 , C12N5/074
CPC分类号： C12N5/0678 , C12N5/0606 , C12N5/0676 , C12N5/0696 , C12N2501/11 , C12N2501/117 , C12N2501/15 , C12N2501/16 , C12N2501/375 , C12N2501/385 , C12N2501/395 , C12N2501/40 , C12N2501/41 , C12N2501/727 , C12N2501/998 , C12N2501/999 , C12N2506/02 , C12N2506/03 , C12N2506/22 , C12N2506/45
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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公开(公告)号：US11104883B2
公开(公告)日：2021-08-31
申请号：US16934503
申请日：2020-07-21
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071 , C12N5/0735 , C12N5/074
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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9.发明申请公开(公告)号：US20170029778A1
公开(公告)日：2017-02-02
申请号：US14898015
申请日：2014-06-11
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gürtler , Alireza Rezania , Benjamin Fryer
IPC分类号： C12N5/071
CPC分类号： C12N5/0678 , C12N5/0606 , C12N5/0676 , C12N5/0696 , C12N2501/11 , C12N2501/117 , C12N2501/15 , C12N2501/16 , C12N2501/375 , C12N2501/385 , C12N2501/395 , C12N2501/40 , C12N2501/41 , C12N2501/727 , C12N2501/998 , C12N2501/999 , C12N2506/02 , C12N2506/03 , C12N2506/22 , C12N2506/45
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
摘要翻译： 本文公开了可用于诱导β细胞成熟的方法，组合物，试剂盒和试剂，以及用于各种应用如细胞治疗的分离的SC-β细胞群体。
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公开(公告)号：US20150240212A1
公开(公告)日：2015-08-27
申请号：US14684129
申请日：2015-04-10
发明人： Quinn P. Peterson , Felicia J. Pagliuca , Douglas A. Melton , Jeffrey R. Millman , Michael Saris Segel , Mads Gurtler
IPC分类号： C12N5/071
CPC分类号： C12N5/0678 , C12N5/0606 , C12N5/0676 , C12N5/0696 , C12N2501/11 , C12N2501/117 , C12N2501/15 , C12N2501/16 , C12N2501/375 , C12N2501/385 , C12N2501/395 , C12N2501/40 , C12N2501/41 , C12N2501/727 , C12N2501/998 , C12N2501/999 , C12N2506/02 , C12N2506/03 , C12N2506/22 , C12N2506/45
摘要： Disclosed herein are methods, compositions, kits, and agents useful for inducing β cell maturation, and isolated populations of SC-β cells for use in various applications, such as cell therapy.
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