-
公开(公告)号：US20240209073A1
公开(公告)日：2024-06-27
申请号：US18422712
申请日：2024-01-25
发明人： Tarlochan S. Nijjar , Robin Barbour , Philip James Dolan, III , Yue Liu , Svetlana Alexander , Mark E. Renz
CPC分类号： C07K16/18 , C12N15/63 , A61K9/0019 , A61K45/06 , C07K2317/565
摘要： The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US20230340094A1
公开(公告)日：2023-10-26
申请号：US18305109
申请日：2023-04-21
发明人： Peter Seubert , Philip James Dolan, III , Yue Liu , Robin Barbour
CPC分类号： C07K16/18 , A61K47/6843 , A61K47/6803 , A61P25/28 , A61K39/0007 , G01N33/6896 , C07K2317/24 , C07K2317/92 , A61K2039/505 , A61K2039/55 , C07K2317/34 , C07K2317/55 , G01N2333/47 , G01N2800/2821
摘要： The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US20230126858A1
公开(公告)日：2023-04-27
申请号：US17937109
申请日：2022-09-30
发明人： Peter Seubert , Philip James Dolan, III , Yue Liu , Robin Barbour
摘要： The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US20220372118A1
公开(公告)日：2022-11-24
申请号：US17089599
申请日：2020-11-04
发明人： Robin Barbour , Philip James Dolan, III , Yue Liu
摘要： The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US10464999B2
公开(公告)日：2019-11-05
申请号：US15201423
申请日：2016-07-02
摘要： The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
-
公开(公告)号：US10407506B2
公开(公告)日：2019-09-10
申请号：US15125570
申请日：2015-03-12
发明人： Yue Liu
IPC分类号： C07K16/00 , C07K16/30 , C12P21/00 , G01N33/577 , G01N33/68
摘要： The invention provides anti-MCAM antibodies that inhibit the ability of human MCAM to bind a laminin alpha-4 chain. The invention also provides pharmaceutical compositions, methods of generating such antibodies, and their use in the manufacture of medicaments for treatment of neuroinflammatory disease, autoimmune disease, or cancer.
-
公开(公告)号：US20160251418A1
公开(公告)日：2016-09-01
申请号：US15009662
申请日：2016-01-28
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/41 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
摘要翻译： 本发明提供了特异性结合转甲状腺素蛋白（TTR）的抗体。 抗体可用于治疗或预防与TTR积累或TTR沉积物积聚（例如，TTR淀粉样变性）相关的疾病或病症。 抗体也可用于诊断TTR淀粉样变性和抑制或减少TTR的聚集，以及其他应用。
-
公开(公告)号：US11643457B2
公开(公告)日：2023-05-09
申请号：US16667647
申请日：2019-10-29
发明人： Peter Seubert , Philip James Dolan, III , Yue Liu , Robin Barbour
CPC分类号： C07K16/18 , A61K39/0007 , A61K47/6803 , A61K47/6843 , A61P25/28 , G01N33/6896 , A61K2039/505 , A61K2039/55 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/92 , G01N2333/47 , G01N2800/2821
摘要： The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US10961302B2
公开(公告)日：2021-03-30
申请号：US16808209
申请日：2020-03-03
发明人： Tarlochan S. Nijjar , Robin Barbour , Philip James Dolan, III , Yue Liu , Svetlana Alexander , Mark E. Renz
摘要： The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
-
公开(公告)号：US20190071491A1
公开(公告)日：2019-03-07
申请号：US16129618
申请日：2018-09-12
摘要： The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
-
-
-
-
-
-
-
-
-
搜索结果
38 条记录 (耗时 0.031 秒)
