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公开(公告)号:US20210199626A1
公开(公告)日:2021-07-01
申请号:US17201822
申请日:2021-03-15
Applicant: Pulmostics Limited
Inventor: Yin Sun
Abstract: A gas chromatography (GC) column system includes an insulation tubing, a metallic GC column disposed within the insulation tubing and having an outer diameter that is less than or equal to an inner diameter of the insulation tubing, a first electrode in contact with the metallic GC column, and a second electrode in contact with the metallic GC column on an opposite side of the insulation tubing from the first electrode. The metallic GC column may be heated by applying a voltage across the first and second electrodes. The voltage may be controlled in response to a measured temperature of the metallic GC column.
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公开(公告)号:US20200011769A1
公开(公告)日:2020-01-09
申请号:US16576021
申请日:2019-09-19
Applicant: Pulmostics Limited
Inventor: Yin Sun
Abstract: A method for identification of chemicals in a sample using a gas chromatograph, a surface acoustic wave (SAW) sensor coupled with the gas chromatograph to define a gas chromatography (GC)/SAW system, and a Raman spectrometer. The method includes receiving SAW frequency response data generated by the SAW sensor, receiving Raman spectrum data generated by the Raman spectrometer, producing a Raman spectrum corresponding to an eluted component of interest based upon an integration of the Raman spectrum data, identifying a set of one or more candidate chemicals for the eluted component of interest based on a corresponding peak of the SAW frequency response data, and searching a Raman database for a match between the produced Raman spectrum and a chemical in the Raman database from among the set of candidate chemicals for the eluted component of interest.
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公开(公告)号:US20200371070A1
公开(公告)日:2020-11-26
申请号:US16992576
申请日:2020-08-13
Applicant: Pulmostics Limited
Inventor: Yin Sun
Abstract: A gas chromatography (GC) column system includes an insulation tubing, a metallic GC column disposed within the insulation tubing and having an outer diameter that is less than or equal to an inner diameter of the insulation tubing, a first electrode in contact with the metallic GC column, and a second electrode in contact with the metallic GC column on an opposite side of the insulation tubing from the first electrode. The metallic GC column may be heated by applying a voltage across the first and second electrodes. The voltage may be controlled in response to a measured temperature of the metallic GC column.
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公开(公告)号:US20200011842A1
公开(公告)日:2020-01-09
申请号:US16575939
申请日:2019-09-19
Applicant: Pulmostics Limited
Inventor: Yin Sun
Abstract: A method for identification of chemicals in a sample using a gas chromatograph and a surface acoustic wave (SAW) sensor coupled with the gas chromatograph to define a gas chromatography (GC)/SAW system. The method includes receiving a temperature profile defining a varying target temperature as a function of time, separating one or more eluted components from a sample with the gas chromatograph, adjusting a temperature of the SAW sensor in accordance with the temperature profile as the one or more eluted components are separated from the sample by the gas chromatograph, generating SAW frequency response data with the SAW sensor, the SAW frequency response data including one or more peaks corresponding respectively to the one or more eluted components separated from the sample, and identifying a set of one or more candidate chemicals for an eluted component of interest based on a corresponding peak of the SAW frequency response data.
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公开(公告)号:US20170338400A1
公开(公告)日:2017-11-23
申请号:US15599358
申请日:2017-05-18
Applicant: Pulmostics Limited
Inventor: Yin Sun
IPC: H01L41/113 , H01L41/053 , G01N29/24 , G01N29/02 , G01N30/76 , G01N29/32 , H01L41/18 , H01L41/047
CPC classification number: H01L41/1132 , G01N29/022 , G01N29/036 , G01N29/2443 , G01N29/2462 , G01N29/32 , G01N30/76 , G01N2291/021 , G01N2291/0255 , H01L41/0472 , H01L41/0533 , H01L41/18
Abstract: A surface acoustic wave sensor in which instrument drift resulting from accumulated surface contamination is minimized. The sensor includes a piezeoelectric substrate defined by an outer surface and a plurality of interdigitated electrodes mounted thereon. The electrodes are defined by one or more exposed portions and an unexposed portion abutting the outer surface of the piezoelectric substrate. An inert coating layer on the outer surface of the piezoelectric substrate and the exposed portions of the electrodes is provided, and can be a perfluoro-silane type compound, a perfluoro-trichloro-silane type compound, a perfluoro-acrylate type compound, polytetrafluoroethylene, or heptadecafluorodecyltrimethoxysilane.
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公开(公告)号:US10600952B2
公开(公告)日:2020-03-24
申请号:US15599358
申请日:2017-05-18
Applicant: Pulmostics Limited
Inventor: Yin Sun
IPC: G01N29/02 , H01L41/113 , G01N1/28 , G01N29/14 , G01N29/24 , G01N29/32 , G01N30/76 , H01L41/047 , H01L41/053 , H01L41/18 , G01N29/036
Abstract: A surface acoustic wave sensor in which instrument drift resulting from accumulated surface contamination is minimized. The sensor includes a piezeoelectric substrate defined by an outer surface and a plurality of interdigitated electrodes mounted thereon. The electrodes are defined by one or more exposed portions and an unexposed portion abutting the outer surface of the piezoelectric substrate. An inert coating layer on the outer surface of the piezoelectric substrate and the exposed portions of the electrodes is provided, and can be a perfluoro-silane type compound, a perfluoro-trichloro-silane type compound, a perfluoro-acrylate type compound, polytetrafluoroethylene, or heptadecafluorodecyltrimethoxysilane.
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公开(公告)号:US20190033275A1
公开(公告)日:2019-01-31
申请号:US16042553
申请日:2018-07-23
Applicant: Pulmostics Limited
Inventor: Yin Sun
IPC: G01N33/00
Abstract: A method for identification of a vapor sample or chemicals in a vapor sample includes introducing a vapor sample to a sensor array including a plurality of sensors, adjusting a temperature of one or more of the plurality of sensors between at least two temperature levels, and identifying the vapor sample or one or more chemicals in the vapor sample based on a plurality of response patterns of the sensor array, each of the response patterns being a collection of responses of the plurality of sensors to the vapor sample with the one or more sensors being at a different temperature level from among the at least two temperature levels.
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公开(公告)号:US20180224354A1
公开(公告)日:2018-08-09
申请号:US15545215
申请日:2017-05-18
Applicant: Pulmostics Limited
Inventor: Yin Sun
CPC classification number: G01N1/10 , G01N1/2202 , G01N21/65 , G01N29/022 , G01N29/036 , G01N30/74 , G01N30/76 , G01N30/78 , G01N30/8675 , G01N2291/02809
Abstract: A method for identification of chemicals in a sample using a gas chromatograph, a surface acoustic wave (SAW) sensor coupled with the gas chromatograph to define a gas chromatography (GC)/SAW system, and a Raman spectrometer. The method includes receiving SAW frequency response data generated by the SAW sensor, receiving Raman spectrum data generated by the Raman spectrometer, producing a Raman spectrum corresponding to an eluted component of interest based upon an integration of the Raman spectrum data, identifying a set of one or more candidate chemicals for the eluted component of interest based on a corresponding peak of the SAW frequency response data, and searching a Raman database for a match between the produced Raman spectrum and a chemical in the Raman database from among the set of candidate chemicals for the eluted component of interest.
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公开(公告)号:US20180024100A1
公开(公告)日:2018-01-25
申请号:US15653256
申请日:2017-07-18
Applicant: Pulmostics Limited
Inventor: Yin Sun
CPC classification number: G01N30/76 , G01N29/022 , G01N29/036 , G01N29/2462 , G01N29/326 , G01N30/8675 , G01N2030/025 , G01N2030/8854 , G01N2291/0215
Abstract: A method for identification of chemicals in a sample using a gas chromatograph and a surface acoustic wave (SAW) sensor coupled with the gas chromatograph to define a gas chromatography (GC)/SAW system. The method includes receiving a temperature profile defining a varying target temperature as a function of time, separating one or more eluted components from a sample with the gas chromatograph, adjusting a temperature of the SAW sensor in accordance with the temperature profile as the one or more eluted components are separated from the sample by the gas chromatograph, generating SAW frequency response data with the SAW sensor, the SAW frequency response data including one or more peaks corresponding respectively to the one or more eluted components separated from the sample, and identifying a set of one or more candidate chemicals for an eluted component of interest based on a corresponding peak of the SAW frequency response data.
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公开(公告)号:US20220065833A1
公开(公告)日:2022-03-03
申请号:US17522803
申请日:2021-11-09
Applicant: Pulmostics Limited
Inventor: Yin Sun
IPC: G01N33/00 , G01N27/12 , G01N29/02 , G01N29/024 , G01N29/24
Abstract: A method for identification of a vapor sample or chemicals in a vapor sample includes introducing a vapor sample to a sensor array including a plurality of sensors, adjusting a temperature of one or more of the plurality of sensors between at least two temperature levels, and identifying the vapor sample or one or more chemicals in the vapor sample based on a plurality of response patterns of the sensor array, each of the response patterns being a collection of responses of the plurality of sensors to the vapor sample with the one or more sensors being at a different temperature level from among the at least two temperature levels.
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