公开(公告)号：US20190022175A1

公开(公告)日：2019-01-24

申请号：US15845955

申请日：2017-12-18

Applicant: Purdue Research Foundation

Inventor： Alyssa Panitch ,  John Eric Paderi ,  Shaili Sharma ,  Katherine Allison Stuart ,  Nelda Marie Vasquez-Portalatin

IPC: A61K38/14 ,  C07K14/47 ,  A61K47/61 ,  C07K9/00 ,  A61K47/54

Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.

公开(公告)号：US09452218B2

公开(公告)日：2016-09-27

申请号：US14383701

申请日：2013-03-08

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Alyssa Panitch ,  Brandon Seal ,  Jamie L. Brugnano ,  Rush L. Bartlett ,  Shaili Sharma ,  James McMasters

IPC: A61K38/08 ,  C07K5/00 ,  A61K47/32 ,  A61K38/16 ,  A61K38/17 ,  A61K47/34 ,  A61K9/51 ,  A61K38/00

CPC classification number: A61K9/5146 ,  A61K38/005 ,  A61K38/08 ,  A61K38/16 ,  A61K38/17 ,  A61K47/32 ,  A61K47/34

Abstract: The invention relates to compositions and methods for the treatment of inflammatory disease states. In particular, the invention relates to the use of a nanoparticle incorporated kinase inhibiting peptide to treat inflammatory disease states.

Abstract translation: 本发明涉及用于治疗炎性疾病状态的组合物和方法。 特别地，本发明涉及纳米颗粒掺入激酶抑制肽来治疗炎性疾病状态的用途。

公开(公告)号：US09872887B2

公开(公告)日：2018-01-23

申请号：US14940990

申请日：2015-11-13

Applicant: Purdue Research Foundation

Inventor： Alyssa Panitch ,  John Eric Paderi ,  Shaili Sharma ,  Katherine Allison Stuart ,  Nelda Marie Vazquez-Portalatin

IPC: C07K9/00 ,  A61K38/14 ,  C07K14/47 ,  A61K47/48

CPC classification number: A61K38/14 ,  A61K47/545 ,  A61K47/61 ,  C07K9/00 ,  C07K14/4725

Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.

公开(公告)号：US10034839B2

公开(公告)日：2018-07-31

申请号：US15233598

申请日：2016-08-10

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Alyssa Panitch ,  Brandon Seal ,  Jamie L. Brugnano ,  Rush L. Bartlett ,  Shaili Sharma ,  James McMasters

IPC: A61K38/00 ,  A61K9/51 ,  A61K38/16 ,  A61K38/17 ,  A61K47/34 ,  A61K47/32 ,  A61K38/08

CPC classification number: A61K9/5146 ,  A61K38/005 ,  A61K38/08 ,  A61K38/16 ,  A61K38/17 ,  A61K47/32 ,  A61K47/34

Abstract: The invention relates to compositions and methods for the treatment of inflammatory disease states. In particular, the invention relates to the use of a nanoparticle incorporated kinase inhibiting peptide to treat inflammatory disease states.

公开(公告)号：US20170035702A1

公开(公告)日：2017-02-09

申请号：US15233598

申请日：2016-08-10

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Alyssa Panitch ,  Brandon Seal ,  Jamie L. Brugnano ,  Rush L. Bartlett ,  Shaili Sharma ,  James McMasters

IPC: A61K9/51 ,  A61K38/08 ,  A61K47/32 ,  A61K38/00

CPC classification number: A61K9/5146 ,  A61K38/005 ,  A61K38/08 ,  A61K38/16 ,  A61K38/17 ,  A61K47/32 ,  A61K47/34

Abstract: The invention relates to compositions and methods for the treatment of inflammatory disease states. In particular, the invention relates to the use of a nanoparticle incorporated kinase inhibiting peptide to treat inflammatory disease states.

Abstract translation: 本发明涉及用于治疗炎性疾病状态的组合物和方法。 特别地，本发明涉及纳米颗粒掺入激酶抑制肽来治疗炎性疾病状态的用途。

公开(公告)号：US20150018279A1

公开(公告)日：2015-01-15

申请号：US14383701

申请日：2013-03-08

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Alyssa Panitch ,  Brandon Seal ,  Jamie L. Brugnano ,  Rush L. Bartlett ,  Shaili Sharma ,  James Mcmasters

IPC: A61K47/32 ,  A61K38/00 ,  A61K38/16

CPC classification number: A61K9/5146 ,  A61K38/005 ,  A61K38/08 ,  A61K38/16 ,  A61K38/17 ,  A61K47/32 ,  A61K47/34

Abstract: The invention relates to compositions and methods for the treatment of inflammatory disease states. In particular, the invention relates to the use of a nanoparticle incorporated kinase inhibiting peptide to treat inflammatory disease states.

Abstract translation: 本发明涉及用于治疗炎性疾病状态的组合物和方法。 特别地，本发明涉及纳米颗粒掺入激酶抑制肽来治疗炎性疾病状态的用途。

公开(公告)号：US20140288002A1

公开(公告)日：2014-09-25

申请号：US14214220

申请日：2014-03-14

Applicant: Purdue Research Foundation

Inventor： Alyssa Panitch ,  John Eric Paderi ,  Shaili Sharma ,  Katherine Allison Stuart ,  Nelda Marie Vazquez-Portalatin

IPC: C07K9/00

CPC classification number: A61K38/14 ,  A61K47/545 ,  A61K47/61 ,  C07K9/00 ,  C07K14/4725

Abstract: This disclosure provides extracellular matrix-binding synthetic peptidoglycans comprised of one or more synthetic peptides conjugated to a glycan and methods of their use.

Abstract translation: 本公开提供了由缀合至聚糖的一种或多种合成肽组成的细胞外基质结合合成肽聚糖及其使用方法。