摘要:
The present invention provides synthetic nucleic acid sequences comprising 10-30 nucleotides of the N1 and N2 gene regions and/or the 3′ non-coding region of the SARS-associated coronavirus Cov-2 (SARS-CoV-2) genome, and a synthetic nucleic acid sequence comprising 10-30 nucleotides of a nucleic acid sequence that is complementary to at least one of those regions. Also provided are compositions comprising the sequences, and uses of the sequences in diagnostic kits. The present invention further provides a primer and probe set for determining the presence or absence of SARS-associated coronavirus Cov-2 in a biological sample, wherein the primer set comprises at least one of the synthetic nucleic acid sequences. Also provided are a composition comprising the primer and probe set, and use of the primer and probe set in a diagnostic kit. Finally, the present invention provides kits and methods for determining the presence or absence of SARS-associated coronavirus Cov-2 (SARS-CoV-2) in a biological sample.
摘要:
The invention provides a method for detecting KRAS mutations at one or more of codons, said method comprising the steps of: (a) extracting DNA from a biological sample; (b) assaying the DNA via PCR for KRAS mutations at one or more of codons with at least one set of oligonucleotides, wherein the at least one set of oligonucleotides comprises an allele specific forward primer, a reverse primer, a probe and a xenonucleic acid clamp to block amplification of wild type DNA. The xenonucleic acid clamps have aza-aza, thio-aza and oxy-aza chemical functionality.
摘要:
The invention provides a method for detecting KRAS mutations at one or more of codons, said method comprising the steps of: (a) extracting DNA from a biological sample; (b) assaying the DNA via PCR for KRAS mutations at one or more of codons with at least one set of oligonucleotides, wherein the at least one set of oligonucleotides comprises an allele specific forward primer, a reverse primer, a probe and a xenonucleic acid clamp to block amplification of wild type DNA. The xenonucleic acid clamps have aza-aza, thio-aza and oxy-aza chemical functionality.
摘要:
Optical film is disclosed. The optical film includes a binder, a plurality of particles, and a plurality of interconnected voids. The volume fraction of the plurality of interconnected voids in the optical film is not less than about 20%. The weight ratio of the binder to the plurality of the particles is not less than about 1:2.
摘要:
Optical film is disclosed. The optical film includes a binder, a plurality of particles, and a plurality of interconnected voids. The volume fraction of the plurality of interconnected voids in the optical film is not less than about 20%. The weight ratio of the binder to the plurality of the particles is not less than about 1:2.
摘要:
The present disclosure discloses a method and device for data transmission between register files. The method includes that: data in a source register file are read at a Stage i of a pipeline; and the read data are transmitted to a destination register file using an idle instruction pipeline. With the method of the present disclosure, data and mask information are transmitted using an idle instruction pipeline, without addition of extra registers for data and control information buffering, thus reducing logic consumption as well as increasing utilization of an existing functional unit.
摘要:
The disclosure provides a device for implementing address buffer management of a processor, including: an assembler configured to perform operations to obtain intermediate values when the assembler encodes a set instruction for an address automatic-increment value and boundary values, and to encapsulate the intermediate values into the set instruction for the address automatic-increment value and boundary values; and a processor configured to determine, according to the intermediate values, whether to perform the address automatic-increment operation or the address automatic-decrement operation, so as to achieve the address buffer management. The disclosure also provides a method for implementing address buffer management of a processor, including: a processor decodes a set instruction for an address automatic-increment value and boundary values to obtain intermediate values, and determines, according to the intermediate values, whether to perform the address automatic-increment operation or the address automatic-decrement operation when the processor performs a load or store instruction, so as to realize the address buffer management. Through the device and the method of the disclosure, the hardware costs of the processor are reduced and design requirements of the processor's time sequence and energy efficiency are met.
摘要:
The present disclosure discloses a method and device for data transmission between register files. The method includes that: data in a source register file are read at a Stage i of a pipeline; and the read data are transmitted to a destination register file using an idle instruction pipeline. With the method of the present disclosure, data and mask information are transmitted using an idle instruction pipeline, without addition of extra registers for data and control information buffering, thus reducing logic consumption as well as increasing utilization of an existing functional unit.
摘要:
The disclosure provides a device for implementing address buffer management of a processor, including: an assembler configured to perform operations to obtain intermediate values when the assembler encodes a set instruction for an address automatic-increment value and boundary values, and to encapsulate the intermediate values into the set instruction for the address automatic-increment value and boundary values; and a processor configured to determine, according to the intermediate values, whether to perform the address automatic-increment operation or the address automatic-decrement operation, so as to achieve the address buffer management. The disclosure also provides a method for implementing address buffer management of a processor, including: a processor decodes a set instruction for an address automatic-increment value and boundary values to obtain intermediate values, and determines, according to the intermediate values, whether to perform the address automatic-increment operation or the address automatic-decrement operation when the processor performs a load or store instruction, so as to realize the address buffer management. Through the device and the method of the disclosure, the hardware costs of the processor are reduced and design requirements of the processor's time sequence and energy efficiency are met.