利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.013 秒)

    Devices and methods for on-line whole blood treatment
    1.
    发明授权
    Devices and methods for on-line whole blood treatment 有权

    公开(公告)号：US10744258B1

    公开(公告)日：2020-08-18

    申请号：US15913729

    申请日：2018-03-06

    申请人： Qualigen Inc.

    发明人： Michael Poirier

    IPC分类号： A61M5/00 ,  A61M5/165 ,  B01D15/38 ,  B01D15/18 ,  B01D15/20 ,  A61M27/00

    摘要： A whole blood treatment device includes a first conduit, a second conduit, and a rotating or reciprocating element having a channel. The first and second conduits are fluidly coupled to the rotating or reciprocating element such that the channel is fluidly continuous with the first conduit when the channel is fluidly discontinuous with the second conduit, and such that the channel is fluidly discontinuous with the first conduit when the channel is fluidly continuous with the second conduit. The first conduit is configured to receive whole blood, and the second conduit is configured to receive a regeneration fluid. The channel comprises a surface that is modified with an affinity agent at a concentration effective to allow removal of a target compound from whole blood.

    WHOLE BLOOD TREATMENT DEVICE AND METHODS OF REMOVING TARGET AGENTS FROM WHOLE BLOOD
    7.
    发明申请
    WHOLE BLOOD TREATMENT DEVICE AND METHODS OF REMOVING TARGET AGENTS FROM WHOLE BLOOD 有权

    公开(公告)号：US20220143291A1

    公开(公告)日：2022-05-12

    申请号：US17434107

    申请日：2020-02-26

    申请人： Qualigen Inc.

    发明人： Michael Poirier

    IPC分类号： A61M1/36 ,  A61P39/06

    摘要： A whole blood treatment device includes a cartridge configured to receive whole blood, having a wall defining an interior volume, an inlet, and an outlet, a support structure having a surface, inside of the cartridge, and an affinity agent, attached to the surface of the support structure. The affinity agent is effective to bind to a target agent that is desirable for removal from a patient. The target agent is selected from the group consisting of: inhibitory checkpoint molecules, inflammatory factors, cancerous cells, autoantibodies, opioids and heavy metals. A method of removing a target agent from whole blood of a patient in a whole blood treatment device comprising pumping whole blood into a cartridge, containing a support structure having a surface, with a plurality of affinity agents on the support structure, to contact the whole blood with the affinity agents; binding the target agent with the affinity agents; and removing the whole blood having a reduced amount of the target agent from the cartridge. The target agent is selected from the group consisting of: inhibitory checkpoint molecules, inflammatory factors, cancerous cells, autoantibodies, opioids and heavy metals.

    Systems and Methods for Sample Verification
    9.
    发明申请
    Systems and Methods for Sample Verification 审中-公开

    公开(公告)号：US20180342062A1

    公开(公告)日：2018-11-29

    申请号：US15755868

    申请日：2015-09-04

    申请人： Qualigen, Inc.

    发明人： Michael Poirier ,  John Stephen Middleton ,  Suzanne Marie Poirier

    IPC分类号： G06T7/13

    摘要： The inventive subject matter is directed to point-of-care analytical devices that accurately determine the volume of test samples using image analysis to improve the accuracy of test results performed on the sample. Most preferably, the image analysis is based on rate changes in optical saturation that parallels sample saturation in a porous structure containing the sample.