公开(公告)号：US06998637B2

公开(公告)日：2006-02-14

申请号：US10600750

申请日：2003-06-19

申请人： R. Johannes Luyken ,  Markus Seitz ,  Jon Preece ,  Werner Weber ,  Günter Schmid

发明人： R. Johannes Luyken ,  Markus Seitz ,  Jon Preece ,  Werner Weber ,  Günter Schmid

IPC分类号： H01L35/24

CPC分类号： H01L51/0591 ,  B82Y10/00 ,  C07D213/22 ,  G11C13/0009 ,  G11C13/0014 ,  H01L27/28 ,  H01L51/0067 ,  H01L51/0072 ,  H01L51/0595

摘要： The circuit element has a first layer composed of an electrically insulating substrate material and a first electrically conductive material which is in the form of at least one discrete area such that it is embedded in the substrate material and/or is applied to the substrate material. Furthermore, it has a second layer having a second electrically conductive material, and a monomolecular layer composed of redox-active bispyridinium molecules, which is arranged between the first layer and the second layer. The bispyridinium molecules are immobilized on the electrically conductive material which is in the form of at least one discrete area, and make electrical contact with the second electrical material of the second layer. Furthermore, electrically inert molecules are immobilized on the first layer, which molecules form a matrix which surrounds the at least one discrete area with the monomolecular layer composed of bispyridinium molecules.

摘要翻译： 电路元件具有由电绝缘衬底材料和至少一个离散区域形式的第一导电材料构成的第一层，使得其嵌入在衬底材料中和/或施加到衬底材料上。 此外，它具有第二层，其具有第二导电材料和由氧化还原活性双吡啶鎓分子组成的单分子层，其被布置在第一层和第二层之间。 双吡啶鎓分子被固定在导电材料上，该导电材料为至少一个离散区域的形式，并与第二层的第二电气材料电接触。 此外，电惰性分子固定在第一层上，该分子形成一个矩阵，该基体围绕至少一个离散的区域，单分子层由双吡啶鎓分子构成。

公开(公告)号：US20050099209A1

公开(公告)日：2005-05-12

申请号：US10600750

申请日：2003-06-19

申请人： R. Luyken ,  Markus Seitz ,  Jon Preece ,  Werner Weber ,  Gunter Schmid

发明人： R. Luyken ,  Markus Seitz ,  Jon Preece ,  Werner Weber ,  Gunter Schmid

IPC分类号： C07D213/22 ,  G11C13/02 ,  H01L27/28 ,  H01L51/30 ,  H03D13/00

CPC分类号： H01L51/0591 ,  B82Y10/00 ,  C07D213/22 ,  G11C13/0009 ,  G11C13/0014 ,  H01L27/28 ,  H01L51/0067 ,  H01L51/0072 ,  H01L51/0595

摘要： The circuit element has a first layer composed of an electrically insulating substrate material and a first electrically conductive material which is in the form of at least one discrete area such that it is embedded in the substrate material and/or is applied to the substrate material. Furthermore, it has a second layer having a second electrically conductive material, and a monomolecular layer composed of redox-active bispyridinium molecules, which is arranged between the first layer and the second layer. The bispyridinium molecules are immobilized on the electrically conductive material which is in the form of at least one discrete area, and make electrical contact with the second electrical material of the second layer. Furthermore, electrically inert molecules are immobilized on the first layer, which molecules form a matrix which surrounds the at least one discrete area with the monomolecular layer composed of bispyridinium molecules.

摘要翻译： 电路元件具有由电绝缘衬底材料和至少一个离散区域形式的第一导电材料构成的第一层，使得其嵌入在衬底材料中和/或施加到衬底材料上。 此外，它具有第二层，其具有第二导电材料和由氧化还原活性双吡啶鎓分子组成的单分子层，其被布置在第一层和第二层之间。 双吡啶鎓分子被固定在导电材料上，该导电材料为至少一个离散区域的形式，并与第二层的第二电气材料电接触。 此外，电惰性分子固定在第一层上，该分子形成一个矩阵，该基体围绕至少一个离散的区域，单分子层由双吡啶鎓分子构成。

公开(公告)号：US20050017759A1

公开(公告)日：2005-01-27

申请号：US10857635

申请日：2004-05-28

申请人： Werner Weber ,  Gunter Schmid ,  Richard Luyken ,  Roland Thewes ,  Markus Seitz

发明人： Werner Weber ,  Gunter Schmid ,  Richard Luyken ,  Roland Thewes ,  Markus Seitz

IPC分类号： G11C13/02 ,  H01L27/28 ,  H01L51/00 ,  H01L51/30 ,  H03D13/00 ,  G01R25/00

CPC分类号： H01L51/0595 ,  B82Y10/00 ,  G11C13/0009 ,  G11C13/0014 ,  G11C2213/15 ,  G11C2213/72 ,  H01L27/28 ,  H01L51/005 ,  H01L51/0053 ,  H01L51/0062 ,  H01L51/0077

摘要： Circuit element having a first layer composed of an electrically insulating substrate material, a first electrically conductive material which is in the form of at least one discrete area, such that it is embedded in or applied to the substrate material, a second layer having a second electrically conductive material, and a monomolecular layer, which is composed of electrically active molecules which transports charge carriers, arranged between the first layer and the second layer. The monomolecular layer is immobilized and makes electrical contact with the second layer. Each of the electrically active molecules has a first unit, which is used as an electron donor, a second unit, which is used as an electron acceptor, wherein the electron donor and the electron acceptor form a diode, and at least one redox-active unit, by means of which a variable resistance is formed, arranged between the first unit and the second unit.

摘要翻译： 具有由电绝缘衬底材料构成的第一层的电路元件，至少一个离散区域形式的第一导电材料，使得其嵌入衬底材料中或施加到衬底材料上，第二层具有第二层 导电材料和单分子层，其由布置在第一层和第二层之间的电荷载流子的电活性分子组成。 单分子层被固定并与第二层电接触。 每个电活性分子具有用作电子给体的第一单元，用作电子受体的第二单元，其中电子给体和电子受体形成二极管，以及至少一种氧化还原活性 单元，其中形成有可变电阻，布置在第一单元和第二单元之间。

公开(公告)号：US07283372B2

公开(公告)日：2007-10-16

申请号：US10857635

申请日：2004-05-28

申请人： Werner Weber ,  Gunter Schmid ,  Richard J. Luyken ,  Roland Thewes ,  Markus Seitz

发明人： Werner Weber ,  Gunter Schmid ,  Richard J. Luyken ,  Roland Thewes ,  Markus Seitz

IPC分类号： H05K7/02 ,  H05K7/06 ,  H05K7/08 ,  H05K7/10

CPC分类号： H01L51/0595 ,  B82Y10/00 ,  G11C13/0009 ,  G11C13/0014 ,  G11C2213/15 ,  G11C2213/72 ,  H01L27/28 ,  H01L51/005 ,  H01L51/0053 ,  H01L51/0062 ,  H01L51/0077

摘要： Circuit element having a first layer composed of an electrically insulating substrate material, a first electrically conductive material which is in the form of at least one discrete area, such that it is embedded in or applied to the substrate material, a second layer having a second electrically conductive material, and a monomolecular layer, which is composed of electrically active molecules which transports charge carriers, arranged between the first layer and the second layer. The monomolecular layer is immobilized and makes electrical contact with the second layer. Each of the electrically active molecules has a first unit, which is used as an electron donor, a second unit, which is used as an electron acceptor, wherein the electron donor and the electron acceptor form a diode, and at least one redox-active unit, by means of which a variable resistance is formed, arranged between the first unit and the second unit.

摘要翻译： 具有由电绝缘衬底材料构成的第一层的电路元件，至少一个离散区域形式的第一导电材料，使得其嵌入衬底材料中或施加到衬底材料上，第二层具有第二层 导电材料和单分子层，其由布置在第一层和第二层之间的电荷载流子的电活性分子组成。 单分子层被固定并与第二层电接触。 每个电活性分子具有用作电子给体的第一单元，用作电子受体的第二单元，其中电子给体和电子受体形成二极管，以及至少一种氧化还原活性 单元，其中形成有可变电阻，布置在第一单元和第二单元之间。

公开(公告)号：US20110230426A1

公开(公告)日：2011-09-22

申请号：US13057932

申请日：2008-08-08

申请人： Daniel Obrecht ,  Frank Gombert ,  Markus Seitz ,  Ludovic T. Maillard ,  Roba Mounme ,  Kerstin Moehle ,  John Anthony Robinson ,  Odile Sellier-Kessler ,  Heiko Henze ,  Christian Bisang ,  Alexander Lederer

发明人： Daniel Obrecht ,  Frank Gombert ,  Markus Seitz ,  Ludovic T. Maillard ,  Roba Mounme ,  Kerstin Moehle ,  John Anthony Robinson ,  Odile Sellier-Kessler ,  Heiko Henze ,  Christian Bisang ,  Alexander Lederer

IPC分类号： A61K38/12 ,  C07K7/64 ,  C07K1/00 ,  A61P3/10 ,  A61P29/00 ,  A61P13/12 ,  A61P9/00 ,  A61P11/06 ,  A61P11/02 ,  A61P11/00

CPC分类号： C07K1/02 ,  C07K7/56 ,  C07K7/64

摘要： Template-fixed β-hairpin peptidomimetics of the general formula wherein Z is a template-fixed chain of 8 α-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid), are Gly or Pro or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have agonizing or antagonizing activity against urotensin II or show inhibition of the STAT6/NCoA-1 interaction and can be used for preventing or treating diseases or disorders related to urotensin II, STAT6 and NCoA-1.These β-hairpin peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.

摘要翻译： 模板固定和通用拟肽模拟物，其中Z是8个α-氨基酸残基的模板固定链，取决于它们在链中的位置（从N-末端氨基酸开始计数）是Gly 或Pro或某些类型，其作为上述公式中的其余符号在说明书和权利要求书及其权利要求书中定义及其盐具有对泌尿生长因子II的激动或拮抗作用或显示STAT6 / NCoA-1相互作用的抑制， 可用于预防或治疗与泌尿前列腺素II，STAT6和NCoA-1相关的疾病或病症。 这些可以通过基于混合固相和溶液相合成策略的方法制造。