公开(公告)号：US20190290787A1

公开(公告)日：2019-09-26

申请号：US16072848

申请日：2017-01-24

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Doron SHABAT ,  Ronit SATCHI-FAINARO ,  Nir HANANYA ,  Ori GREEN ,  Tal EILON

IPC: A61K49/00 ,  C07H15/26 ,  C07F5/04 ,  C07F9/655 ,  C09K11/06 ,  C09B11/24 ,  C09B23/08 ,  C09B23/04

Abstract: Dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and π* acceptor group-containing dioxetane based chemiluminescence probes can be included in compositions. The chemiluminescence probes are useful for both diagnostics and in vivo imaging.

公开(公告)号：US20200237932A1

公开(公告)日：2020-07-30

申请号：US16850333

申请日：2020-04-16

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Doron SHABAT ,  Ronit SATCHI-FAINARO ,  Nir HANANYA ,  Ori GREEN ,  Tal EILON

IPC: A61K49/00 ,  C07H15/26 ,  C07F9/12 ,  C09B11/24 ,  C07D321/00 ,  C07F7/18 ,  C09B23/01 ,  C09B23/04 ,  C07F5/02 ,  C07F5/04 ,  C09B23/08 ,  C07F9/655 ,  C09K11/06 ,  C07H15/203

Abstract: The present invention provides dioxetane-based chemiluminescence probes, more specifically fluorophore-tethered dioxetane-based chemiluminescence probes and compositions thereof. The chemiluminescence probes disclosed are useful for both diagnostics and in vivo imaging.