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公开(公告)号：US11474017B2
公开(公告)日：2022-10-18
申请号：US17003470
申请日：2020-08-26
Applicant: RION Co., Ltd.
Inventor： Kazuma Sekimoto
Abstract: A microbial particle measuring apparatus includes: a light emitter configured to irradiate a fluid with light of a predetermined wavelength over a predetermined measurement time; a fluorescence receiver configured to selectively receive fluorescence emitted from particles contained in the fluid and output a signal having a magnitude corresponding to intensity of the fluorescence; a signal acquisition unit configured to obtain the signal output from the fluorescence receiver at regular intervals over the measurement time; and a determiner configured to calculate a slope of waveform of the signal obtained by the signal acquisition unit, and determine a concentration of microbial particles contained in the fluid using an attenuation amount of fluorescence intensity generated in a time period in which the slope in the measurement time is smaller than a predetermined value as an amount of attenuation derived from the microbial particles.
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公开(公告)号：US20150211977A1
公开(公告)日：2015-07-30
申请号：US14410620
申请日：2013-06-25
Applicant: RION CO., LTD.
Inventor： Kazuma Sekimoto , Kazuo Ichijyo
IPC: G01N15/14
CPC classification number: G01N15/1404 , G01N15/06 , G01N15/10 , G01N15/1434 , G01N15/1459 , G01N2001/2223 , G01N2015/0046 , G01N2015/0693 , G01N2015/1486
Abstract: A particle counting system includes a collector, a liquid input/output operation executing means, and a particle counter. The collector performs a collecting operation to introduce the surrounding air into a container storing a liquid to collect airborne particles in the liquid. The liquid input/output operation executing means executes a series of liquid input/output operations to supply an additional liquid for the collecting operation to the collector and discharge the liquid after the collecting operation from the collector. The particle counter measures the number of particles contained in the liquid discharged from the collector with the series of liquid input/output operations.
Abstract translation: 粒子计数系统包括收集器，液体输入/输出操作执行装置和粒子计数器。 收集器执行收集操作以将周围的空气引入容纳液体的容器中以收集液体中的空气中的颗粒。 液体输入/输出操作执行装置执行一系列液体输入/输出操作，以向收集器提供用于收集操作的附加液体，并且在收集操作之后将液体排出。 颗粒计数器通过一系列液体输入/输出操作来测量从集电器排出的液体中所含的颗粒数。
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Patent Agency Ranking
3.发明授权Apparatus for counting viable particles in liquid in real time, dialysis fluid monitoring system and purified water monitoring system using the apparatus, and method of counting viable particles in liquid in real time 有权用于实时计数液体中的活粒子的装置，使用该装置的透析液监测系统和净化水监测系统，以及实时计数液体中的有效颗粒的方法公开(公告)号：US09267845B2
公开(公告)日：2016-02-23
申请号：US14292535
申请日：2014-05-30
Applicant: RION CO., LTD.
Inventor： Kazuo Ichijyo , Kazuma Sekimoto , Kousei Sekigawa , Yukihiro Kimoto , Takayuki Kosaka
CPC classification number: G01J3/4406 , A61M1/16 , A61M1/1605 , A61M1/168 , A61M2205/3306 , A61M2205/52 , C02F1/008 , C02F1/44 , C02F2209/003 , C02F2209/005 , C02F2209/105 , G01N15/1459 , G01N21/6428 , G01N21/645 , G01N2015/1486
Abstract: A viable particle counting apparatus 77 includes devices 10, 70, 2. The device 10 radiates a light with a predetermined wavelength toward a liquid containing a detection target. The device 70 reduces a Raman-scattered light emitted from the liquid out of lights emitted due to an interaction of the light radiated by the device 10 with the target or the liquid and selects an autofluorescence light emitted from the target. The device 2 determines whether or not the target contained in the liquid is a viable particle, based on a light obtained after the Raman-scattered light is reduced by the device 70. The device 10 radiates the light with a wavelength that causes the autofluorescence light and the Raman-scattered light to be different in peak wavelength.
Abstract translation: 可行的颗粒计数装置77包括装置10,70,2。装置10将含有预定波长的光朝向包含检测对象的液体辐射。 装置70减少由于由装置10照射的光与目标物或液体的相互作用而发出的从发射的光中发出的拉曼散射光，并选择从目标射出的自发荧光。 装置2基于在通过装置70减少拉曼散射光之后获得的光来确定包含在液体中的靶是否是活的颗粒。装置10以引起自发荧光的波长辐射光 并且拉曼散射光的峰值波长不同。
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公开(公告)号：US09250174B2
公开(公告)日：2016-02-02
申请号：US14410620
申请日：2013-06-25
Applicant: RION CO., LTD.
Inventor： Kazuma Sekimoto , Kazuo Ichijyo
CPC classification number: G01N15/1404 , G01N15/06 , G01N15/10 , G01N15/1434 , G01N15/1459 , G01N2001/2223 , G01N2015/0046 , G01N2015/0693 , G01N2015/1486
Abstract: A particle counting system includes a collector, a liquid input/output operation executing means, and a particle counter. The collector performs a collecting operation to introduce the surrounding air into a container storing a liquid to collect airborne particles in the liquid. The liquid input/output operation executing means executes a series of liquid input/output operations to supply an additional liquid for the collecting operation to the collector and discharge the liquid after the collecting operation from the collector. The particle counter measures the number of particles contained in the liquid discharged from the collector with the series of liquid input/output operations.
Abstract translation: 粒子计数系统包括收集器，液体输入/输出操作执行装置和粒子计数器。 收集器执行收集操作以将周围的空气引入容纳液体的容器中以收集液体中的空气中的颗粒。 液体输入/输出操作执行装置执行一系列液体输入/输出操作，以向收集器提供用于收集操作的附加液体，并且在收集操作之后将液体排出。 颗粒计数器通过一系列液体输入/输出操作来测量从集电器排出的液体中所含的颗粒数。
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公开(公告)号：US11215551B2
公开(公告)日：2022-01-04
申请号：US14766578
申请日：2014-01-20
Applicant: RION CO., LTD.
Inventor： Kazuma Sekimoto
Abstract: A particle counting system includes a particle counting means and pre-stage irradiation means. The particle counting means counts particles existing in a fluid by irradiating the fluid containing target particles with light at a predetermined wavelength, separating selectively autofluorescence or phosphorescence emitted from the target particles by the radiated light, receiving the separated autofluorescence or phosphorescence, and determining that the target particles are the particles according to the received autofluorescence or phosphorescence. The pre-stage irradiation means irradiates the fluid with ultraviolet light in advance before the particle counting means irradiates the fluid with the light at the predetermined wavelength. The particle counting means includes a band-pass filter that allows light having a wavelength of 450 nm to 600 nm to pass therethrough.
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公开(公告)号：US11119027B2
公开(公告)日：2021-09-14
申请号：US16461199
申请日：2017-11-07
Applicant: RION Co., Ltd.
Inventor： Kazuma Sekimoto
Abstract: A microbial particle is accurately counted in distinction from a non-microbial particle. A preceding-stage irradiation section 2 irradiates a sample as fluid with ultraviolet light at a preceding stage of a microbial particle counter 1. The ultraviolet light is ultraviolet light having a deep ultraviolet region, the ultraviolet light increasing the fluorescence intensity of a first autofluorescence substance in the microbial particle. The microbial particle counter 1 measures light intensity in a first wavelength range including the fluorescence wavelength of the first autofluorescence substance. In addition, the microbial particle counter 1 measures light intensity in a specific second wavelength range. Further, the microbial particle counter 1 counts the microbial particle in distinction from a non-microbial particle in the fluid based on the measured light intensity in the first wavelength range and the measured light intensity in the specific second wavelength range.
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公开(公告)号：US10094763B2
公开(公告)日：2018-10-09
申请号：US15681000
申请日：2017-08-18
Applicant: RION Co., Ltd.
Inventor： Kazuma Sekimoto
Abstract: A microviable particle counting system includes: a microviable particle counting instrument configured to detect autofluorescence of a microviable particle in a sample as fluid, thereby counting the microviable particle in the sample; and a former-stage irradiator provided at a former stage of the microviable particle counting instrument to irradiate the sample with ultraviolet light. The ultraviolet light contains first ultraviolet light having such a wavelength that a carbon-carbon covalent bond is disconnected, and the first ultraviolet light has a wavelength shorter than 200 nm.
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