公开(公告)号：US20120158067A1

公开(公告)日：2012-06-21

申请号：US13406073

申请日：2012-02-27

申请人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

发明人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

IPC分类号： A61B17/88

CPC分类号： A61B17/8811 ,  A61B17/70 ,  A61B17/8852

摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.

摘要翻译： 提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。 工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。 插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。 注射套管用于将流体材料注入到堆叠中和/或周围。 在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。 在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。 含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

公开(公告)号：US20120316568A1

公开(公告)日：2012-12-13

申请号：US13587283

申请日：2012-08-16

申请人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

发明人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

IPC分类号： A61B17/66

CPC分类号： A61B17/8811 ,  A61B17/70 ,  A61B17/8852

摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.

摘要翻译： 提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。 工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。 插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。 注射套管用于将流体材料注入到堆叠中和/或周围。 在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。 在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。 含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

公开(公告)号：US20110004217A1

公开(公告)日：2011-01-06

申请号：US12858530

申请日：2010-08-18

申请人： RIchard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

发明人： RIchard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

IPC分类号： A61B17/66

CPC分类号： A61B17/8811 ,  A61B17/70 ,  A61B17/8852

摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.

摘要翻译： 提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。 工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。 插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。 注射套管用于将流体材料注入到堆叠中和/或周围。 在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。 在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。 含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

公开(公告)号：US07789912B2

公开(公告)日：2010-09-07

申请号：US11031562

申请日：2005-01-07

申请人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

发明人： Richard Manzi ,  Tyler Lipschultz ,  Peter Barreiro ,  Mark D. LoGuidice ,  Thomas Wilson ,  Steve Wysocki

IPC分类号： A61B17/58

CPC分类号： A61B17/8811 ,  A61B17/70 ,  A61B17/8852

摘要： A system and method is provided for distracting opposite surfaces from the interior of a bone, such as a vertebral body. A working channel cannula provides a working channel through which an inserter and an injection cannula can simultaneously pass. The inserter transports a plurality of wafers into the interior of the bone to form a load-bearing stack bearing against the opposite surfaces. The injection cannula is used to inject a fluent material into and/or around the stack. In certain embodiments, the fluent material is a load-bearing or hardenable material, such as bone cement. In other embodiments, the fluent material can be a BMP, HAP, or other osteo-inductive, osteo-conductive, or pharmaceutical compositions. A syringe containing the fluent material is engaged to the injection cannula and is operable to inject the fluent material into the vertebral body under controlled pressure.

摘要翻译： 提供了一种系统和方法，用于从骨骼的内部（例如椎体）分散相对表面。 工作通道套管提供工作通道，插入器和注射套管可以通过该工作通道同时通过。 插入器将多个晶片传送到骨的内部以形成抵靠相对表面的承载堆叠轴承。 注射套管用于将流体材料注入到堆叠中和/或周围。 在某些实施方案中，流动材料是承载或可硬化材料，例如骨粘固剂。 在其它实施方案中，流感材料可以是BMP，HAP或其它骨诱导性，骨诱导性或药物组合物。 含有流动材料的注射器与注射套管接合并且可操作以在受控的压力下将流体材料注入椎体中。

公开(公告)号：US07875078B2

公开(公告)日：2011-01-25

申请号：US11211347

申请日：2005-08-25

申请人： Steve Wysocki ,  Joseph N. Logan ,  Richard Manzi ,  Robert D. Paxson ,  John Pafford ,  Mark D. LoGuidice ,  Tyler P. Lipschultz ,  Carl Michael Nilsson ,  Daniel S. Savage

发明人： Steve Wysocki ,  Joseph N. Logan ,  Richard Manzi ,  Robert D. Paxson ,  John Pafford ,  Mark D. LoGuidice ,  Tyler P. Lipschultz ,  Carl Michael Nilsson ,  Daniel S. Savage

IPC分类号： A61F2/44

CPC分类号： A61F2/447 ,  A61B2017/0256 ,  A61F2/442 ,  A61F2/4425 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/4611 ,  A61F2002/30383 ,  A61F2002/30476 ,  A61F2002/30492 ,  A61F2002/3052 ,  A61F2002/30556 ,  A61F2002/30599 ,  A61F2002/30601 ,  A61F2002/30904 ,  A61F2002/448 ,  A61F2220/0025 ,  A61F2250/0009 ,  A61F2250/0063

摘要： An expandable interbody fusion device for implantation into the intradiscal space between two opposing vertebral bodies of a spine comprises a superior endplate member having an upper surface for engaging a superior vertebral body in a spine, and an inferior endplate member having a lower surface for engaging an inferior vertebral body in the spine. The superior endplate member and the inferior endplate member are releasably coupled and define a cavity therebetween. At least one expansion member is configured to be introduced into the cavity to move the superior endplate and the inferior endplate members relatively apart upon introduction and to thereby decouple the superior endplate member and the inferior endplate member. An inserter may be releasably coupled to the device to facilitate insertion of the device as well as to provide a track for insertion of the expansion members.

摘要翻译： 用于植入脊柱的两个相对椎体之间的椎间盘内空间的可扩展的椎体间融合装置包括具有用于与脊柱中的上椎体接合的上表面的上端板构件，以及具有下表面的下端板构件 脊椎下椎体。 上端板构件和下端板构件可释放地联接并且在它们之间限定空腔。 至少一个膨胀构件被构造成引入空腔中，以在引入时使上端板和下端板构件相对分开，从而使上端板构件和下端板构件分离。 插入器可以可释放地联接到装置以便于装置的插入以及提供用于插入扩张构件的轨道。

公开(公告)号：US20090254123A1

公开(公告)日：2009-10-08

申请号：US12432247

申请日：2009-04-29

申请人： John Pafford ,  Thomas Wilson ,  Lawrence M. Boyd ,  Mark D. LoGuidice

发明人： John Pafford ,  Thomas Wilson ,  Lawrence M. Boyd ,  Mark D. LoGuidice

IPC分类号： A61B17/70 ,  A61B17/88

CPC分类号： A61B17/701 ,  A61B17/7007

摘要： A dynamic stabilization system includes a stabilization element, such as a spinal rod, a plurality of bone anchors, such as bone bolts, and a like plurality of connectors for connecting the bolts to the spinal rod. At least some of the connectors include a flexible element between the bone anchor and the rod and an adjustment element for adjusting the flexibility of the flexible element, to thereby adjust the dynamic flexibility between the rod and the bone anchor. In one embodiment, the flexible element is a flexible bearing element of a rod end bearing.

摘要翻译： 动态稳定系统包括稳定元件，例如脊椎杆，多个骨锚，例如骨螺栓，以及用于将螺栓连接到脊柱杆的多个连接器。 至少一些连接器包括在骨锚和杆之间的柔性元件和用于调节柔性元件的柔性的调节元件，从而调节杆和骨锚之间的动态弹性。 在一个实施例中，柔性元件是杆端轴承的柔性支承元件。

公开(公告)号：US20100318190A1

公开(公告)日：2010-12-16

申请号：US12861037

申请日：2010-08-23

申请人： Keith Collins ,  Thomas S. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

发明人： Keith Collins ,  Thomas S. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

IPC分类号： A61F2/44

CPC分类号： A61F2/4657 ,  A61B17/70 ,  A61B17/8811 ,  A61B17/8827 ,  A61B2017/0256 ,  A61B2017/564 ,  A61F2/4611 ,  A61F2/4684 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2002/4663 ,  A61M29/02

摘要： A method for treating a diseased or damaged spinal disc comprises the steps of: (a) providing access to the nucleus pulposus through the annulus; (b) removing at least a portion of the nucleus pulposus to create an intradiscal space; (c) determining the size of the intradiscal space; and (d) sealably introducing under pressure a curable biomaterial through the annulus directly into the intradiscal space. The step of determining the size of the intradiscal space may be accomplished by expanding a compliant balloon within the intradiscal space using a contrast medium capable of visualization under fluoroscopy. The curable material is sealably introduced through a vented needle inserted through the opening. The curable biomaterial is introduced until a quantity of the material flows into the vent.

摘要翻译： 用于治疗患病或损伤的椎间盘的方法包括以下步骤：（a）通过所述环提供进入髓核的通路; （b）去除髓核的至少一部分以产生椎间盘内空间; （c）确定椎间盘内空间的大小; 和（d）在压力下可密封地将可固化生物材料通过环形物直接引入椎间盘内空间。 确定椎间盘内空间大小的步骤可以通过使用能够在荧光透视下可视化的造影剂来扩展椎间盘内空间内的顺应气囊来实现。 可固化材料通过穿过开口插入的通气针密封地引入。 引入可固化的生物材料，直到一定量的材料流入通气口。

公开(公告)号：US07789913B2

公开(公告)日：2010-09-07

申请号：US11170577

申请日：2005-06-29

申请人： Keith Collins ,  Thomas G. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

发明人： Keith Collins ,  Thomas G. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

IPC分类号： A61F2/44

CPC分类号： A61F2/4657 ,  A61B17/70 ,  A61B17/8811 ,  A61B17/8827 ,  A61B2017/0256 ,  A61B2017/564 ,  A61F2/4611 ,  A61F2/4684 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2002/4663 ,  A61M29/02

摘要： A method for treating a diseased or damaged spinal disc comprises the steps of: (a) providing access to the nucleus pulposus through the annulus; (b) removing at least a portion of the nucleus pulposus to create an intradiscal space; determining the size of the intradiscal space; and (c) sealably introducing under pressure a curable biomaterial through the annulus directly into the intradiscal space. The method may include the additional steps of applying a force to distract the opposing vertebral bodies about the intradiscal space and then removing the distraction force after the biomaterial has cured. The step of determining the size of the intradiscal space may be accomplished by expanding a compliant balloon within the intradiscal space using a contrast medium capable of visualization under fluoroscopy. The curable material is sealably introduced through a vented needle inserted through the opening. The curable biomaterial is introduced until a quantity of the material flows into the vent.

摘要翻译： 用于治疗患病或损伤的椎间盘的方法包括以下步骤：（a）通过所述环提供进入髓核的通路; （b）去除髓核的至少一部分以产生椎间盘内空间; 确定椎间盘内空间的大小; 和（c）在压力下可密封地将可固化生物材料通过环形物直接引入椎间盘内空间。 该方法可以包括额外的步骤：施加力以分散相对的椎体围绕椎间盘内空间，然后在生物材料固化后去除牵引力。 确定椎间盘内空间大小的步骤可以通过使用能够在荧光透视下可视化的造影剂来扩展椎间盘内空间内的顺应气囊来实现。 可固化材料通过穿过开口插入的通气针密封地引入。 引入可固化的生物材料，直到一定量的材料流入通气口。

公开(公告)号：US07722579B2

公开(公告)日：2010-05-25

申请号：US11170010

申请日：2005-06-29

申请人： Keith Collins ,  Lawrence Boyd ,  Andrew Carter ,  Dennis Lee ,  John Pafford ,  Jared Walkenhorst ,  Thomas G. Wilson ,  Mark D. LoGuidice ,  Lance Middlelton

发明人： Keith Collins ,  Lawrence Boyd ,  Andrew Carter ,  Dennis Lee ,  John Pafford ,  Jared Walkenhorst ,  Thomas G. Wilson ,  Mark D. LoGuidice ,  Lance Middlelton

IPC分类号： A61M25/00

CPC分类号： A61F2/4657 ,  A61B17/70 ,  A61B17/8811 ,  A61B17/8827 ,  A61B2017/0256 ,  A61B2017/564 ,  A61F2/4611 ,  A61F2/4684 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2002/4663 ,  A61M29/02

摘要： A vented needle assembly is provided for sealably injecting biomaterial into an intradiscal space interiorly of the annulus of a spinal disc and for providing an exhaust for the intradiscal space. The vented needle assembly comprises a compressible seal body for pressing against an outer surface of the annulus, and a needle extending through the seal. The needle may be configured to connect to a syringe for pressure injection of the biomaterial. The seal includes a vent extending therethrough with an opening for communication with the intradiscal space and an opening for the discharge of excess biomaterial filling the intradiscal space. A kit of parts is also provided for use in the treatment of a spinal disc, the kit comprising the vented needle assembly and an inflatable trial device. The trial device is removably introduced into the intradiscal space and inflated to determine the available size of the intradiscal space.

摘要翻译： 提供了一种排气针组件，用于将生物材料密封地注入椎间盘环的内部的椎间盘内空间，并为椎间盘内空间提供排气。 排气针组件包括用于压靠环形空间的外表面的可压缩密封体和延伸穿过密封件的针。 针可以被配置为连接到注射器以用于压力注射生物材料。 密封件包括通过其延伸的通气口，其具有用于与椎间盘内空间连通的开口和用于排出填充椎间盘内空间的多余生物材料的开口。 还提供了一套用于治疗脊椎盘的部件，该套件包括通气针组件和可充气试验装置。 试验装置可拆卸地引入椎间盘内空间并充气以确定椎间盘内空间的可用尺寸。

公开(公告)号：US08444694B2

公开(公告)日：2013-05-21

申请号：US12861037

申请日：2010-08-23

申请人： Keith Collins ,  Thomas G. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

发明人： Keith Collins ,  Thomas G. Wilson ,  Jared Walkenhorst ,  Dennis Lee ,  Andrew Carter ,  John Pafford ,  Mark D. LoGuidice ,  Lance Middleton ,  Lawrence Boyd

IPC分类号： A61F2/44

CPC分类号： A61F2/4657 ,  A61B17/70 ,  A61B17/8811 ,  A61B17/8827 ,  A61B2017/0256 ,  A61B2017/564 ,  A61F2/4611 ,  A61F2/4684 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2002/4663 ,  A61M29/02

摘要： A method for treating a diseased or damaged spinal disc comprises the steps of: (a) providing access to the nucleus pulposus through the annulus; (b) removing at least a portion of the nucleus pulposus to create an intradiscal space; (c) determining the size of the intradiscal space; and (d) sealably introducing under pressure a curable biomaterial through the annulus directly into the intradiscal space. The step of determining the size of the intradiscal space may be accomplished by expanding a compliant balloon within the intradiscal space using a contrast medium capable of visualization under fluoroscopy. The curable material is sealably introduced through a vented needle inserted through the opening. The curable biomaterial is introduced until a quantity of the material flows into the vent.

摘要翻译： 用于治疗患病或损伤的椎间盘的方法包括以下步骤：（a）通过所述环提供进入髓核的通路; （b）去除髓核的至少一部分以产生椎间盘内空间; （c）确定椎间盘内空间的大小; 和（d）在压力下可密封地将可固化生物材料通过环形物直接引入椎间盘内空间。 确定椎间盘内空间大小的步骤可以通过使用能够在荧光透视下可视化的造影剂来扩展椎间盘内空间内的顺应气囊来实现。 可固化材料通过穿过开口插入的通气针密封地引入。 引入可固化的生物材料，直到一定量的材料流入通气口。