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    AQUEOUS OPHTHALMIC COMPOSITION
    3.
    发明申请
    AQUEOUS OPHTHALMIC COMPOSITION 审中-公开

    公开(公告)号：US20170105934A1

    公开(公告)日：2017-04-20

    申请号：US15317851

    申请日：2015-06-09

    Applicant: ROHTO Pharmaceutical Co., Ltd.

    Inventor： Yoko Mizutare ,  Yasuko Matsumura

    IPC: A61K9/08 ,  A61K47/12 ,  A61K47/10 ,  A61K47/18 ,  A61K47/02 ,  A61K9/00 ,  A61K47/26

    CPC classification number: A61K9/08 ,  A61K9/0048 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/26

    Abstract: An aqueous ophthalmic composition is provided comprising at least one component which is selected from the group consisting of a polysaccharide, a monosaccharide, at least one vitamin component selected from the group consisting of vitamin B12, vitamin B2, vitamin A and panthenol, at least one oil component selected from the group consisting of a plant oil, an animal oil and a mineral oil, at least one surfactant selected from the group consisting of polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene glycol and polyoxyl stearate, an anti-allergic component, a preservative, a thickening component, a polyhydric alcohol, an anti-inflammatory component, an anti-bacterial agent and a cooling and/or refreshing agent; and (B) a buffering agent. When the composition is brought into contact with a polybutylene terephthalate-containing resin container, the container can be prevented from weight change, deterioration and wetting and can be improved in a liquid cutting property.

    ANTI-AGING AGENT CONTAINING ARCTIGENIN DERIVATIVE
    6.
    发明申请
    ANTI-AGING AGENT CONTAINING ARCTIGENIN DERIVATIVE 有权
    含有ARCTIGENIN衍生物的抗衰老剂

    公开(公告)号：US20150093345A1

    公开(公告)日：2015-04-02

    申请号：US14389200

    申请日：2013-03-27

    Applicant: ROHTO Pharmaceutical Co., Ltd.

    Inventor： Yuya Hayashi ,  Yoko Mizutare

    IPC: A61K8/49 ,  C07D307/33 ,  A61Q19/08 ,  A61Q19/02

    CPC classification number: A61K8/4973 ,  A61K31/365 ,  A61K2800/782 ,  A61Q19/02 ,  A61Q19/08 ,  C07D307/33

    Abstract: An arctigenin derivative used for anti-aging treatment, including protection of the skin from the sun and recovery of skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are used as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivatives are particularly useful as an external agent for the skin, such as an anti-inflammatory external agent, a sunscreen external agent, or an external agent for recovering elasticity.

    Abstract translation: 用于抗衰老治疗的抗坏血酸衍生物衍生物，包括保护皮肤免受太阳和恢复皮肤弹性。 各种脂肪酸酯衍生物，醇醚衍生物和烷基化衍生物用作抗坏血酸生成素衍生物。 制备用于控制ET-1产生的药剂，弹性蛋白酶抑制剂和抗炎剂。 这样的抗坏血酸衍生物特别可用作皮肤的外用剂，例如抗炎外用剂，防晒外用剂或用于回收弹性的外用剂。

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