公开(公告)号：US3714153A

公开(公告)日：1973-01-30

申请号：US3714153D

申请日：1970-06-22

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  BUENDIA J

IPC: A01N53/04 ,  A01N53/10 ,  C07D207/38 ,  C07D307/45 ,  C07D307/54 ,  C07D307/58 ,  C07D333/32 ,  C09B23/00

CPC classification number: C07D307/42 ,  C07D207/38 ,  C07D307/54 ,  C07D307/58 ,  C07D333/32

Abstract: Novel 3,3-dimethyl-2-(2''-oxo-3''-x-cyclopentylidenemethyl)-1cyclopropanecarboxylic acids of a cis or trans structure, in the form of racemic mixtures or optically active isomers of the formula

WHEREIN X is selected from the group consisting of oxygen, sulfur and imino and R is selected from the group consisting of hydrogen, lower alkyl of one to six carbons, a radical of the formula

WHEREIN Y3 is aryl such as phenyl, and a radical of the formula

WHEREIN Z is alkenyl or alkadienyl such as allyl, butenyl and pentadienyl and their preparation and intermediates therefor.

Abstract translation: 具有下式的外消旋混合物或光学活性异构体的顺式或反式结构的新的3,3-二甲基-2-（2'-氧代-3'-x-环戊基亚甲基）-1-环丙烷甲酸为式WHEREIN X 选自氧，硫和亚氨基，R选自氢，1至6个碳的低级烷基，式WHEREIN Y 3为芳基如苯基的基团和式 其中Z是烯基或链二烯基，例如烯丙基，丁烯基和戊二烯基及其制备方法和中间体。

公开(公告)号：US3842177A

公开(公告)日：1974-10-15

申请号：US32984773

申请日：1973-02-05

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  BUENDIA J

IPC: A01N53/04 ,  A01N53/10 ,  C07D207/38 ,  C07D307/45 ,  C07D307/54 ,  C07D307/58 ,  C07D333/32 ,  A01N9/12 ,  A01N9/22 ,  A01N9/24

CPC classification number: C07D307/42 ,  C07D207/38 ,  C07D307/54 ,  C07D307/58 ,  C07D333/32

Abstract: 1. AN INSECTIDAL COMPOSITION COMPRISING AN INSECTICIDALLY EFFECTIVE AMOUNT OF A COMPOUND SELECTED FROM THE GROUP CONSISTING OFF OPTICALLY ACTIVE AND RACEMIC MIXTURES OF A COMPOUND OF THE FORMULA

1-((-CO-X-CH2-CH2-)>C=CH-),2-(R-OOC-),3,3-DI(H3C-)-

CYCLOPROPANE

WHEREIN X IS SELECTED FROM THE GROUP CONSISTING OF OXYGEN AND SULFUR AND R IS SELECTED FROM THE GROUP CONSISTING OF ALKYL OF 1 TO 6 CARBON ATOMS, A RADICAL OF THE FORMULA

-CH2-(FURYLENE)-CH2-Y3

WHEREIN Y3 IS PHENYL, AND A RADICAL OF THE FORMULA WHEREIN Z IS SELECTED FROM THE GROUP CONSISTING OF ALKENYL OF 2 TO 7 CARBON ATOMS AND ALKADIENYL OF 4 TO 7 CARBON ATOMS; AND AN INERT CARRIER.

公开(公告)号：US3786070A

公开(公告)日：1974-01-15

申请号：US3786070D

申请日：1970-03-02

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  BUENDIA J

IPC: C07D311/94 ,  A01N20060101 ,  C07C20060101 ,  C07C51/00 ,  C07C61/00 ,  C07C61/04 ,  C07C61/16 ,  C07C61/37 ,  C07C67/00 ,  C07C69/04 ,  C07C69/74 ,  C07D7/18

CPC classification number: C07D493/04

Abstract: A PROCESS FOR THE PREPARATION OF RACEMIC CIS CHRYSANTHEMIC ACID OR OF THE (1R,2S) CONFIGURATION OR OF THE (1S,2R) CONFIGURATION BEGINNING RESPECTIVELY FROM RACEMIC TRANS 3,3-DIMETHYL-2-(2''-HYDROXY-2''-METHYLPROPYL)-CYCLOPROPANEL-CARBOXYLIC ACID OR OF THE (1S,2S) CONFIGURATION OR OF THE (1R,2R) CONFIGURATION.

公开(公告)号：US3801623A

公开(公告)日：1974-04-02

申请号：US3801623D

申请日：1971-04-28

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  TOROMANOFF E ,  BUENDIA J

IPC: C07C59/90 ,  C07C405/00 ,  C07D309/12 ,  C07C69/36 ,  C07C69/74

CPC classification number: C07C405/00 ,  C07C59/90 ,  C07D309/12

Abstract: NOVEL PROSTANOIC ACID DERIVATIVES OF THE FORMULA

2-R1,2-(R-OOC-(CH2)N-CH=CH-CH2-),3-(CH3-(CH2)M-CH(-O-R3)-

CH=CH-),5-R2-CYCLOPENTANONE

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