公开(公告)号：US3818059A

公开(公告)日：1974-06-18

申请号：US19752771

申请日：1971-11-10

Applicant: ROUSSEL UCLAF

Inventor： HAINAUT D ,  TOROMANOFF E ,  DEMOUTE J

IPC: C07C45/69 ,  C07C49/203 ,  C07C51/09 ,  C07C51/353 ,  C07C69/587 ,  C07F1/02 ,  C07F9/40 ,  C07F9/54 ,  C07C51/00 ,  C07C57/02 ,  C07C69/52

CPC classification number: C07F9/5428 ,  C07C45/69 ,  C07C49/203 ,  C07C51/09 ,  C07C51/353 ,  C07C69/587 ,  C07F1/02 ,  C07F9/4006 ,  C07C57/52 ,  C07C57/03

Abstract: A novel process for the preparation of alkyl 3,11-dimethyl-7ethyl-2,6,10-tridecatrienoate wherein alkyl is a hydrocarbon of one to five carbon atoms in a semi-stereospecific manner which are useful intermediates for the preparation of juvenile hormone and to novel intermediates therefor.

Abstract translation: 一种制备3,11-二甲基-7-乙基-2,2,10-十三碳三烯酸烷基酯的新方法，其中烷基是半立体特异性方式的1至5个碳原子的烃，其是制备 幼体激素及其新型中间体。

公开(公告)号：US3798236A

公开(公告)日：1974-03-19

申请号：US3798236D

申请日：1972-07-25

Applicant: ROUSSEL UCLAF

Inventor： HAINAUT D ,  TOROMANOFF E ,  DEMOUTE J

IPC: A61K31/00 ,  A61M25/02 ,  C07C17/093 ,  C07D263/32 ,  C07D277/22 ,  C07D277/24 ,  C07D277/30 ,  C07F3/02 ,  C07D65/08

CPC classification number: C07D277/22 ,  A61K31/00 ,  A61M25/02 ,  C07C17/093 ,  C07D263/32 ,  C07D277/24 ,  C07D277/30 ,  C07F3/02 ,  C07C21/14

Abstract: PRODUCTS HAVING THE FORMULA:

1-((O)N-),2-(ALK-OOC-CH=C(-CH3)-CH2-),4-(CH3-CH2-C(-CH3)=

CH-CH2-CH2-)-5,6-DIHYDRO-2H-THIOPYRAN

WHEREIN N REPRESENTS AN INTEGER FROM 0 TO 1 AND ALK REPRESENTS AN ALKYL HAVING FROM 1 TO 5 CARBON ATOMS. THESE COMPOUNDS POSSESS REMARKABLE INSECTICIDAL PROPERTIES AND ARE INTERMEDIATES IN THE SYNTHESIS OF THE JUVENILE HORMONE.

公开(公告)号：US3832353A

公开(公告)日：1974-08-27

申请号：US27510772

申请日：1972-07-25

Applicant: ROUSSEL UCLAF

Inventor： DEMOUTE J ,  HAINAUT D ,  TOROMANOFF E

IPC: A61K31/00 ,  A61M25/02 ,  C07C17/093 ,  C07D263/32 ,  C07D277/22 ,  C07D277/24 ,  C07D277/30 ,  C07F3/02 ,  C07D65/08

CPC classification number: C07D277/22 ,  A61K31/00 ,  A61M25/02 ,  C07C17/093 ,  C07D263/32 ,  C07D277/24 ,  C07D277/30 ,  C07F3/02 ,  C07C21/14

Abstract: WHEREIN N IS O OR 1 AND ESPECIALLY THE Z ISOMERS WHICH HAVE REMARKABLE INSECTICIDAL PROPERTIES AND ARE INTERMEDIATES IN THE SYNTHESIS OF JUVENILE HORMONE AND THEIR PREPARATION.
THIOPYRAN

1-(O=)N,4-(CH3-CH2-C(-CH3)=CH-CH2-CH2-),5,6-DIHYDRO-2H-

NOVEL 2H-THIAPYRANS OF THE FORMULA:

公开(公告)号：US3801623A

公开(公告)日：1974-04-02

申请号：US3801623D

申请日：1971-04-28

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  TOROMANOFF E ,  BUENDIA J

IPC: C07C59/90 ,  C07C405/00 ,  C07D309/12 ,  C07C69/36 ,  C07C69/74

CPC classification number: C07C405/00 ,  C07C59/90 ,  C07D309/12

Abstract: NOVEL PROSTANOIC ACID DERIVATIVES OF THE FORMULA

2-R1,2-(R-OOC-(CH2)N-CH=CH-CH2-),3-(CH3-(CH2)M-CH(-O-R3)-

CH=CH-),5-R2-CYCLOPENTANONE

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

公开(公告)号：US3770724A

公开(公告)日：1973-11-06

申请号：US3770724D

申请日：1971-03-22

Applicant: ROUSSEL UCLAF

Inventor： TOROMANOFF E ,  WARNANT J ,  FARCILLI A

IPC: C07D401/02 ,  C07D461/00 ,  C07D471/14 ,  C07D471/22 ,  C07D99/02

CPC classification number: C07D471/14 ,  C07D461/00

Abstract: PROCESS FOR PREPARING PENTACYCLIC ALKLOIDS OF GENERAL FORMULA:

12-(CH3-OOC-),12-HO,13A-(CH3-CH2-)-1,2,5,6,12,13-3H-
INDOLO(3,2,1-DE)PYRIDO(3,2,1-IJ)(1,5)NAPHTHYRIDINE

公开(公告)号：US3736319A

公开(公告)日：1973-05-29

申请号：US3736319D

申请日：1971-04-28

Applicant: ROUSSEL UCLAF

Inventor： MARTEL J ,  TOROMANOFF E

IPC: C07C62/38 ,  C07C51/00 ,  C07C69/74 ,  C07C405/00 ,  C07D303/42 ,  C07D309/12 ,  C07D521/00 ,  C07D7/04

CPC classification number: C07D231/12 ,  C07C405/00 ,  C07D233/56 ,  C07D249/08 ,  C07D303/42 ,  C07D309/12

Abstract: NOVEL ALKYL 3-(3'' - OR - TRANS 1''-ALKENYL)-CYCLOPENTANONE-2-CARBOXYLATES OF THE FORMULA

2-(ALK-OOC-),3-(CH3-(CH2)M-CH(-O-R)-CH=CH-)CYCLOPENTAN-1-

ONE

WHEREIN ALK IS ALKYL OF 1 TO 7 CARBON ATOMS, R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ACYL OF AN ORGANIC CARBOXYLIC ACID OF 1 TO 18 CARBON ATOMS AND A-TETRAHYDROPYRANYL AND M IS 3, 4 OR 5 WHICH ARE INTERMEDIATES FOR PROSTAGLANDINS AND THEIR PREPARATION AND NOVEL INTERMEDIATES.