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公开(公告)号：US4610998A
公开(公告)日：1986-09-09
申请号：US807432
申请日：1985-12-09
IPC分类号： A61K31/415 , A61P7/02 , C07D233/54 , C07D233/60 , C07D521/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： The invention is concerned with the novel imidazolylethoxy indanes represented by formula (I), ##STR1## or a pharmacologically-acceptable salt thereof, a process for the preparation of them, and a pharmaceutical composition which contains these new compounds as active ingredient and can be used as antithrombotic and platelet antiaggregating agents.
摘要翻译： 本发明涉及式（I），（I），或其药理学上可接受的盐所代表的新的咪唑并 - 乙氧基二氢化茚，其制备方法和含有这些新化合物作为活性成分的药物组合物 并可用作抗血栓形成和血小板抗聚集剂。
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2.发明授权Process for preparing a 2,3-dihydro-1H-imidazolyl-ethoxy indene antithrombotic agent and its pharmaceutically acceptable salts 失效2,3-二氢-1H-咪唑基 - 乙氧基茚抗血栓形成剂及其药学上可接受的盐的制备方法
公开(公告)号：US4843165A
公开(公告)日：1989-06-27
申请号：US135040
申请日：1987-12-18
IPC分类号： A61K31/415 , A61P7/02 , C07C62/06 , C07C62/14 , C07C62/32 , C07C62/34 , C07C69/635 , C07C69/757 , C07C255/47 , C07D233/60 , C07D521/00 , C07F7/18
CPC分类号： C07D231/12 , C07C62/32 , C07C62/34 , C07D233/56 , C07D249/08 , C07F7/1856
摘要： A process is disclosed for preparing a 2,3-dihydro-1H-imidazolylethoxy indene antithrombotic agent and its pharmaceutically acceptable salts.
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3.发明授权Thiophene ring-substituted .alpha.-(alkylaminopropionyl)-thiophenes and the method for preparing the same 失效噻吩环取代的α-（烷基氨基丙酰基） - 噻吩及其制备方法
公开(公告)号：US4719225A
公开(公告)日：1988-01-12
申请号：US936706
申请日：1986-12-01
申请人： Rafael Foguet , Ernesto Forne , Aurelio Sacristan , Jose A. Ortiz
发明人： Rafael Foguet , Ernesto Forne , Aurelio Sacristan , Jose A. Ortiz
IPC分类号： A61K31/38 , A61K31/381 , A61P25/24 , A61P25/26 , C07D333/22 , C07D333/28
CPC分类号： C07D333/22 , C07D333/28
摘要： The invention is concerned with the novel thiophene ring-substituted .alpha.-(alkylaminopropionyl)-thiophenes represented by the formula (I), ##STR1## or a pharmaceutically-acceptable salt thereof, a process for the preparation of them, and a pharmaceutical composition which contains these new compounds as active ingredient and can be used as antidepressant agents.
摘要翻译： 本发明涉及由式（I）表示的新颖的噻吩环取代的α-（烷基氨基丙酰基） - 噻吩，或其药学上可接受的盐，其制备方法和 含有这些新化合物作为活性成分并可用作抗抑郁剂的药物组合物。
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公开(公告)号：US4859675A
公开(公告)日：1989-08-22
申请号：US207375
申请日：1988-06-15
申请人： Rafael Foguet , Ernesto Forne , Aurelio Sacristan , Jose A. Ortiz
发明人： Rafael Foguet , Ernesto Forne , Aurelio Sacristan , Jose A. Ortiz
IPC分类号： C07D295/02 , A61K31/495 , A61P25/24 , A61P25/26 , C07D241/00 , C07D295/03 , C07D295/033 , C07D295/06 , C07D295/073 , C07D295/08 , C07D295/096
CPC分类号： C07D295/033 , C07D295/03 , C07D295/073 , C07D295/096
摘要： An 1-[2-(phenylmethyl)phenyl]piperazine of the formula (I), ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein R.sub.1 is hydrogen, C.sub.1-4 alkyl or halogen, R.sub.2 is hydrogen, C.sub.1-4 alkyl, halogen or C.sub.1-4 alkoxy and R.sub.3 is hydrogen or methyl.such compounds are useful as antidepressive agents.
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