公开(公告)号：US20120265001A1

公开(公告)日：2012-10-18

申请号：US13271172

申请日：2011-10-11

Applicant: Ramazan Asmatulu ,  Heath Misak ,  Shang-you Yang ,  Paul Wooley

Inventor： Ramazan Asmatulu ,  Heath Misak ,  Shang-you Yang ,  Paul Wooley

IPC: A61K9/14 ,  A61K31/519 ,  A61K33/24 ,  A61P35/00 ,  A61N2/10 ,  A61K47/34 ,  A61K31/513 ,  A61P29/00 ,  B82Y5/00

CPC classification number: A61K9/0009 ,  A61K9/5031 ,  A61K9/5094

Abstract: A composite magnetic nanoparticle drug delivery system provides targeted controlled release chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceutical composition. The composite nanoparticles are prepared by oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the magnetic nanoparticles to affected areas. The biological targeting agent draws the nanoparticles into the affected tissues. Polymer degradation provides controlled time release delivery of the pharmaceutical agent.

Abstract translation: 复合磁性纳米颗粒药物递送系统为癌性肿瘤和炎性疾病提供靶向控释药物治疗。 磁性纳米颗粒包括生物相容性和可生物降解的聚合物，磁性纳米颗粒，生物靶向剂人血清白蛋白和治疗药物组合物。 复合纳米颗粒由油包油乳液/溶剂蒸发和高剪切混合制备。 外部施加的磁场将磁性纳米颗粒吸引到受影响的区域。 生物靶向剂将纳米颗粒吸引到受影响的组织中。 聚合物降解提供药剂的受控时间释放递送。

公开(公告)号：US20140283348A1

公开(公告)日：2014-09-25

申请号：US14298597

申请日：2014-06-06

Applicant: Ramazan Asmatulu

Inventor： Ramazan Asmatulu

IPC: D06B9/06 ,  D06B1/02 ,  D06B3/18

CPC classification number: B29B17/02 ,  B29B2017/0293 ,  B29K2063/00 ,  B29K2105/06 ,  B29K2105/0872 ,  Y02W30/622

Abstract: A method for recycling a fiber laminae, the fiber laminae being impregnated with a partially cured resin, the partially cured resin being expired, the method comprising steps of jetting a solvent toward the fiber laminae; extracting the partially cured resin from the fiber laminae, said extraction being effected by impingements of the solvent jet against the fiber laminae's impregnated partially cured resin; and drying the fiber laminae.

Abstract translation: 一种用于再循环纤维层的方法，所述纤维层被部分固化的树脂浸渍，所述部分固化的树脂被过期，所述方法包括向所述纤维层喷射溶剂的步骤; 从纤维层中提取部分固化的树脂，所述提取通过溶剂射流冲击纤维层浸渍的部分固化的树脂来实现; 并干燥纤维层。

公开(公告)号：US09782342B2

公开(公告)日：2017-10-10

申请号：US13271172

申请日：2011-10-11

Applicant: Ramazan Asmatulu ,  Heath Misak ,  Shang-You Yang ,  Paul Wooley

Inventor： Ramazan Asmatulu ,  Heath Misak ,  Shang-You Yang ,  Paul Wooley

IPC: A61M37/00 ,  A61K9/00 ,  A61K33/24 ,  A61K9/50

CPC classification number: A61K9/0009 ,  A61K9/5031 ,  A61K9/5094

Abstract: A composite magnetic nanoparticle drug delivery system provides targeted controlled release chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceutical composition. The composite nanoparticles are prepared by oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the magnetic nanoparticles to affected areas. The biological targeting agent draws the nanoparticles into the affected tissues. Polymer degradation provides controlled time release delivery of the pharmaceutical agent.

公开(公告)号：US06440316B1

公开(公告)日：2002-08-27

申请号：US09531373

申请日：2000-03-21

Applicant: Roe-Hoan Yoon ,  Ramazan Asmatulu

Inventor： Roe-Hoan Yoon ,  Ramazan Asmatulu

IPC: B01D17038

CPC classification number: F26B5/14 ,  B04B3/00 ,  B04B15/08 ,  B04B15/12 ,  F26B5/08 ,  F26B21/10

Abstract: Methods of improving the efficiency of solid-liquid separation during centrifugal filtration have been developed. They consist of increasing the pressure drop across the filter cake using extraneous means such as increasing the gas pressure inside a filter chamber and/or applying vacuum on the outside. The extraneous means of increasing the pressure drop is designed to increase the rate of removing liquid (water) during the drainage period of the centrifugal filtration process and, hence, lower the amount of the residual liquid (water) left in the filter cake.

Abstract translation: 已经开发了提高离心过滤中固液分离效率的方法。 它们包括使用诸如增加过滤室内的气体压力和/或在外部施加真空的外部手段来增加滤饼上的压降。 设计增加压降的无关手段旨在提高在离心过滤过程的排水期间除去液体（水）的速度，从而降低滤饼中残留的残留液体（水）的量。