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    PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING
    7.
    发明申请
    PHYSIOLOGICALLY BALANCED, IONIZED, ACIDIC SOLUTION AND METHODOLOGY FOR USE IN WOUND HEALING 审中-公开
    生理平衡，离子化，酸解决方案和方法用于创伤治疗

    公开(公告)号：US20080279963A1

    公开(公告)日：2008-11-13

    申请号：US12053536

    申请日：2008-03-21

    申请人： Ramin Najafi ,  Lu Wang ,  Mansour Bassiri ,  Jane Yang

    发明人： Ramin Najafi ,  Lu Wang ,  Mansour Bassiri ,  Jane Yang

    IPC分类号： A61K33/14 ,  A61P17/02

    CPC分类号： A01N59/00 ,  A61K9/0048 ,  A61K31/74 ,  A61K33/14 ,  A61K33/24 ,  A61K33/30 ,  A61K33/40 ,  C01B11/04 ,  C02F1/4618 ,  C02F2001/46185 ,  C02F2103/026 ,  C02F2201/46115 ,  C02F2201/4618 ,  C02F2209/04 ,  C02F2209/06 ,  C02F2303/04 ,  A01N2300/00 ,  A61K2300/00

    摘要： Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride. A typical electrolyzed solution of the present invention has a pH within the range of about 2 to about 5, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and hypohalous acid concentration in the range of about 10 ppm to about 200 ppm. The solution has bactericidal, fungicidal, and sporicidal properties. The composition of the invention is nontoxic and has antibacterial properties, and is useful in any application in which antimicrobial properties are desirable.

    摘要翻译： 本文描述的是生理平衡的酸性溶液。 通常，溶液通过化学反应或通过电解包含无机盐的混合物以形成生理平衡溶液的溶液来制备。 本发明还涉及使用该溶液的方法，包括可与溶液组合使用的专门的绷带，或任选地与其它局部施用的材料一起使用。 使用无机盐和任选的矿物质的混合物，以模拟等渗状态的电解质浓度和体液混合物。 该溶液通常包含锂，钠，钾，钙和其它阳离子的一种卤化物盐。 通常，卤化物是氟化物，氯化物，溴化物或碘化物，最典型的是氯化物。 本发明的典型的电解溶液的pH值在约2至约5的范围内，氧化还原电位在约+ 600mV至约+ 1200mV范围内，次卤酸浓度在约10ppm范围内 至约200ppm。 该溶液具有杀菌，杀真菌和杀孢子的特性。 本发明的组合物是无毒的并且具有抗菌性质，并且可用于需要抗微生物性质的任何应用中。

    N,N-dihalogenated amino acids and derivatives
    9.
    发明授权
    N,N-dihalogenated amino acids and derivatives 有权
    N，N-二卤代氨基酸及其衍生物

    公开(公告)号：US07462361B2

    公开(公告)日：2008-12-09

    申请号：US10920636

    申请日：2004-08-17

    申请人： Mansour Bassiri ,  Ramin Najafi ,  Lu Wang ,  Jane Yang

    发明人： Mansour Bassiri ,  Ramin Najafi ,  Lu Wang ,  Jane Yang

    IPC分类号： A61K9/54 ,  C07C69/86

    CPC分类号： C07C239/04 ,  A01N41/08 ,  A01N59/00 ,  C07C309/14

    摘要： The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

    摘要翻译： 本发明涉及活性杀菌，抗细菌，抗感染，抗微生物，杀芽孢，消毒剂，抗真菌和抗病毒化合物和组合物以及这些组合物在治疗中的新用途。 本说明书还描述了新化合物和组合物的使用方法。 本说明书还描述了制备这些化合物的方法。

    Physiologically balanced, ionized, acidic solution and methodology for use in wound healing
    10.
    发明授权
    Physiologically balanced, ionized, acidic solution and methodology for use in wound healing 有权
    生理平衡，电离，酸性溶液和用于伤口愈合的方法

    公开(公告)号：US07393522B2

    公开(公告)日：2008-07-01

    申请号：US10655493

    申请日：2003-09-03

    申请人： Ramin Najafi ,  Lu Wang ,  Mansour Bassiri ,  Jane Yang

    发明人： Ramin Najafi ,  Lu Wang ,  Mansour Bassiri ,  Jane Yang

    IPC分类号： A61K31/74 ,  A61K33/40 ,  A61K33/14

    CPC分类号： A01N59/00 ,  A61K9/0048 ,  A61K31/74 ,  A61K33/14 ,  A61K33/24 ,  A61K33/30 ,  A61K33/40 ,  C01B11/04 ,  C02F1/4618 ,  C02F2001/46185 ,  C02F2103/026 ,  C02F2201/46115 ,  C02F2201/4618 ,  C02F2209/04 ,  C02F2209/06 ,  C02F2303/04 ,  A01N2300/00 ,  A61K2300/00

    摘要： Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride. A typical electrolyzed solution of the present invention has a pH within the range of about 2 to about 5, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and hypohalous acid concentration in the range of about 10 ppm to about 200 ppm. The solution has bactericidal, fungicidal, and sporicidal properties. The composition of the invention is nontoxic and has antibacterial properties, and is useful in any application in which antimicrobial properties are desirable.

    摘要翻译： 本文描述的是生理平衡的酸性溶液。 通常，溶液通过化学反应或通过电解包含无机盐的混合物以形成生理平衡溶液的溶液来制备。 本发明还涉及使用该溶液的方法，包括可与溶液组合使用的专门的绷带，或任选地与其它局部施用的材料一起使用。 使用无机盐和任选的矿物质的混合物，以模拟等渗状态的电解质浓度和体液混合物。 该溶液通常包含锂，钠，钾，钙和其它阳离子的一种卤化物盐。 通常，卤化物是氟化物，氯化物，溴化物或碘化物，最典型的是氯化物。 本发明的典型的电解溶液的pH值在约2至约5的范围内，氧化还原电位在约+ 600mV至约+ 1200mV范围内，次卤酸浓度在约10ppm范围内 至约200ppm。 该溶液具有杀菌，杀真菌和杀孢子的特性。 本发明的组合物是无毒的并且具有抗菌性质，并且可用于需要抗微生物性质的任何应用中。