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公开(公告)号：US20080143955A1
公开(公告)日：2008-06-19
申请号：US11611283
申请日：2006-12-15
申请人： Ravi Sharma , Robert M. Braun , Jay F. Kunzler , Yu-Chin Lai , Daniel M. Ammon
发明人： Ravi Sharma , Robert M. Braun , Jay F. Kunzler , Yu-Chin Lai , Daniel M. Ammon
CPC分类号： G02B1/043
摘要： A silicone contact lens has a silicate coating on at least one of the contact lens surfaces. The silicate coating is anchored to the bulk silicone contact lens material with a non-silicone polymer layer.
摘要翻译： 有机硅隐形眼镜在至少一个隐形眼镜表面上具有硅酸盐涂层。 硅酸盐涂层用非硅氧烷聚合物层锚固到体积硅胶隐形眼镜材料。
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公开(公告)号：US20080143956A1
公开(公告)日：2008-06-19
申请号：US11611317
申请日：2006-12-15
申请人： Ravi Sharma , Robert M. Braun , Daniel M. Ammon , Jay F. Kunzler , Yu-Chin Lai
发明人： Ravi Sharma , Robert M. Braun , Daniel M. Ammon , Jay F. Kunzler , Yu-Chin Lai
CPC分类号： B29D11/00076 , C08G18/61 , C08J7/12 , C08J2351/00 , C08J2383/04 , C08L75/16
摘要： At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens.
摘要翻译： 硅酮隐形眼镜的至少一个表面是起皱的表面，为隐形眼镜表面提供所需的形貌。 起皱的表面可以包括在透镜的整个表面上的任意隆起，或者在透镜的表面上以期望的图案。
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3.发明申请Drug delivery systems based on degradible cationic siloxanyl macromonomers 失效基于降解阳离子硅氧烷基大分子单体的药物输送系统公开(公告)号：US20080075780A1
公开(公告)日：2008-03-27
申请号：US11527913
申请日：2006-09-27
申请人： Jay F. Kunzler , Derek Schorzman , Daniel M. Ammon
发明人： Jay F. Kunzler , Derek Schorzman , Daniel M. Ammon
IPC分类号： A61K9/14 , C08F255/00
CPC分类号： A61K9/0051 , A61K47/34
摘要： Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X−, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein.
摘要翻译： 基于一种或多种以下通式的含硅单体的基质控制扩散药物递送系统：其中L，X-O，n，R 1，R 2，R 3，R 4，R 5，R 6，R 7和V 如本文所述。
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公开(公告)号：US20080153938A1
公开(公告)日：2008-06-26
申请号：US11934937
申请日：2007-11-05
IPC分类号： C08F2/46
CPC分类号： C08F2/52 , G02B1/043 , C08L51/085
摘要： A method for treating the surface of a fluorinated biomedical device is provided comprising the steps of (a) plasma treating the fluorinated biomedical device with a hydrogen-containing atmosphere to reduce the fluorine or C—F bonding content of the fluorinated biomedical device; and (b) subjecting the hydrogen plasma treated surface to a plasma-polymerization reaction in a hydrocarbon-containing atmosphere to form a polymeric carbonaceous layer on the surface of the biomedical device.
摘要翻译： 提供了一种处理氟化生物医学装置表面的方法，包括以下步骤：（a）用含氢气氛对含氟生物医学装置进行等离子体处理，以降低氟化生物医学装置的氟或C-F键合含量; 和（b）使氢等离子体处理的表面在含烃气氛中进行等离子体聚合反应，以在生物医学装置的表面上形成聚合碳质层。
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公开(公告)号：US20080150177A1
公开(公告)日：2008-06-26
申请号：US11613360
申请日：2006-12-20
CPC分类号： B29D11/00125 , B29C59/14 , B29L2011/0041 , C08J7/123 , C08J2383/04
摘要： A method for treating a surface of a fluorinated silicone-containing ophthalmic device is provided, the method comprising plasma treating the fluorinated silicone-containing ophthalmic device with a hydrogen-containing atmosphere in the presence of an oxidizing source thereby increasing the wettability and/or biocompatibility of the device.
摘要翻译： 提供了一种用于处理含氟硅氧烷的眼科装置的表面的方法，该方法包括在氧化源的存在下用含氢气体等离子体处理含氟聚硅氧烷的眼科装置，从而增加润湿性和/或生物相容性 的设备。
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公开(公告)号：US20070161810A1
公开(公告)日：2007-07-12
申请号：US11611512
申请日：2006-12-15
IPC分类号： C07F7/10
CPC分类号： C07F7/0838 , C08G77/388
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers prepared by the process disclosed herein.
摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子单体。 这些性质包括用水提取聚合的医疗装置的能力。 这避免了使用本领域典型的有机溶剂。 聚合物组合物包含通过本文公开的方法制备的聚合的阳离子亲水硅氧烷基单体。
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7.发明申请Use of aroma compounds as defoaming agents for ophthalmic solutions with high concentrations of surfactants 审中-公开使用芳香化合物作为具有高浓度表面活性剂的眼用溶液的消泡剂公开(公告)号：US20070148099A1
公开(公告)日：2007-06-28
申请号：US11611331
申请日：2006-12-15
IPC分类号： A61K9/12 , A61K31/045 , A61K31/05 , A61K31/075
CPC分类号： A61L12/08 , A61K9/0048 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/075
摘要： A method of reducing foam formation and improving odor in ophthalmic solutions, such as multipurpose cleaning and conditioning solutions and contact lens packing solutions. The ophthalmic solutions contain surfactant and aroma compound in an amount effective to decrease foam formation. The aroma compound has a low molecular weight and pleasing smell.
摘要翻译： 一种减少泡沫形成并改善眼科溶液中气味的方法，如多用途清洁和调理溶液和隐形眼镜包装溶液。 眼用溶液含有有效降低泡沫形成量的表面活性剂和芳香化合物。 芳香化合物具有低分子量和令人愉悦的气味。
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公开(公告)号：US07021761B2
公开(公告)日：2006-04-04
申请号：US10187153
申请日：2002-06-28
IPC分类号： G02C7/04
摘要： A lens with a colored portion is composed of a lens-forming polymer having a front lens surface and a back lens surface. A colorant is applied to at least one of these surfaces, and these surfaces may be coated with a coating layer composed of a material different than the lens-forming polymer. In the case of a cosmetic contact lens, the colorant may be applied in an annular ring pattern corresponding to an iris, so that the colorant pattern masks and changes the apparent color of the natural iris when the contact lens is worn.
摘要翻译： 具有着色部分的透镜由具有前透镜表面和后透镜表面的透镜形成聚合物组成。 将着色剂施加到这些表面中的至少一个，并且这些表面可以涂覆有由不同于透镜形成聚合物的材料构成的涂层。 在化妆品隐形眼镜的情况下，着色剂可以以对应于虹膜的环形图案施加，使得着色剂图案掩蔽和改变隐形眼镜佩戴时天然虹膜的表观颜色。
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公开(公告)号：US20080151180A1
公开(公告)日：2008-06-26
申请号：US11872305
申请日：2007-10-15
IPC分类号： G02C7/04
CPC分类号： C08J7/04 , A61L12/14 , Y10T428/31504
摘要： A contact lens is coated with a first polymer, such as a boronic acid-containing copolymer, having affinity to mucin, and a second polymer. The second polymer improves initial comfort of the contact lens. During wear of the contact lens, the second polymer is removed from the contact lens, by blinking and/or tear fluids, and mucin complexes with the first polymer on the contact lens surface.
摘要翻译： 隐形眼镜涂覆有对粘蛋白具有亲和性的第一聚合物，例如含硼酸的共聚物和第二聚合物。 第二种聚合物提高了隐形眼镜的初始舒适度。 在隐形眼镜的磨损期间，通过在接触透镜表面上闪烁和/或撕裂流体和与第一聚合物的粘蛋白复合物从隐形眼镜去除第二聚合物。
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公开(公告)号：US07147326B2
公开(公告)日：2006-12-12
申请号：US11332006
申请日：2006-01-13
IPC分类号： G02C7/04
摘要： A lens with a colored portion is composed of a lens-forming polymer having a front lens surface and a back lens surface. A colorant is applied to at least one of these surfaces, and these surfaces may be coated with a coating layer composed of a material different than the lens-forming polymer. In the case of a cosmetic contact lens, the colorant may be applied in an annular ring pattern corresponding to an iris, so that the colorant pattern masks and changes the apparent color of the natural iris when the contact lens is worn.
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