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公开(公告)号：US20110201711A1
公开(公告)日：2011-08-18
申请号：US12708019
申请日：2010-02-18
IPC分类号： C08L75/12
摘要： A bone defect filler for implantation in a bone defect of a patient includes a particulate polymer distributed within a polymeric binder. The particulate polymer includes a plurality of particles, which may have substantially the same material composition as the polymeric binder. The particles of the particulate polymer may be formed in a variety of shapes and/or sizes to provide the bone defect filler with improved pore interconnectivity, material expansion and contamination characteristics, while maintaining sufficient mechanical strength and handling characteristics for bone repair applications. The bone defect filler also provides the flexibility to be molded or shaped in situ to fill the bone defect.
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公开(公告)号：US08338498B2
公开(公告)日：2012-12-25
申请号：US12708019
申请日：2010-02-18
IPC分类号： C08L75/04
摘要： A bone defect filler for implantation in a bone defect of a patient includes a particulate polymer distributed within a polymeric binder. The particulate polymer includes a plurality of particles, which may have substantially the same material composition as the polymeric binder. The particles of the particulate polymer may be formed in a variety of shapes and/or sizes to provide the bone defect filler with improved pore interconnectivity, material expansion and contamination characteristics, while maintaining sufficient mechanical strength and handling characteristics for bone repair applications. The bone defect filler also provides the flexibility to be molded or shaped in situ to fill the bone defect.
摘要翻译： 用于植入患者骨缺损的骨缺损填料包括分布在聚合物粘合剂内的颗粒聚合物。 颗粒聚合物包括多个颗粒，其可以具有与聚合物粘合剂基本相同的材料组成。 颗粒状聚合物的颗粒可以以各种形状和/或尺寸形成，以提供具有改善的孔互连性，材料膨胀和污染特性的骨缺损填料，同时保持骨修复应用的足够的机械强度和处理特性。 骨缺损填料还提供在原位成型或成形以填充骨缺损的柔性。
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公开(公告)号：US20110201704A1
公开(公告)日：2011-08-18
申请号：US12962161
申请日：2010-12-07
IPC分类号： C08J9/00 , C09J175/04
CPC分类号： C08G18/10 , A61L27/48 , A61L27/56 , A61L2430/02 , C08G18/7664 , C08J9/0085 , C08J9/24 , C08J9/33 , C08J2375/04 , C08J2475/04 , C08L75/04 , C08G18/36
摘要： A bone defect filler for implantation in a bone defect of a patient includes a particulate polymer distributed within a polymeric binder. The particulate polymer includes a plurality of particles, which may have substantially the same material composition as the polymeric binder. The particles of the particulate polymer may be formed in a variety of shapes and/or sizes to provide the bone defect filler with improved pore interconnectivity, material expansion and contamination characteristics, while maintaining sufficient mechanical strength and handling characteristics for bone repair applications. The bone defect filler also provides the flexibility to be molded or shaped in situ to fill the bone defect.
摘要翻译： 用于植入患者骨缺损的骨缺损填料包括分布在聚合物粘合剂内的颗粒聚合物。 颗粒聚合物包括多个颗粒，其可以具有与聚合物粘合剂基本相同的材料组成。 颗粒状聚合物的颗粒可以以各种形状和/或尺寸形成，以提供具有改善的孔互连性，材料膨胀和污染特性的骨缺损填料，同时保持骨修复应用的足够的机械强度和处理特性。 骨缺损填料还提供在原位成型或成形以填充骨缺损的柔性。
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公开(公告)号：US20120065641A1
公开(公告)日：2012-03-15
申请号：US12881626
申请日：2010-09-14
IPC分类号： A61B17/58 , A61K31/765 , A61P19/08 , A61K31/74
CPC分类号： A61K31/74 , A61B17/68 , A61B17/823 , A61K31/765
摘要： A bone repair apparatus includes a partially polymerized biocompatible adhesive provided in a state wherein polymerization of the biocompatible adhesive is substantially suspended. A method for repairing a bone defect includes preparing the biocompatible adhesive, suspending polymerization of the biocompatible adhesive prior to full cure, delivering the biocompatible adhesive to the bone defect while polymerization is substantially suspended and accelerating polymerization of the biocompatible adhesive to achieve full cure. The method provides an implanted biocompatible adhesive with a malleable osteoconductive structure without compromising the physical characteristics of the biocompatible adhesive, thereby improving handling and delivery of the bone adhesive.
摘要翻译： 骨修复装置包括在生物相容性粘合剂的聚合基本上悬浮的状态下提供的部分聚合的生物相容性粘合剂。 修复骨缺损的方法包括制备生物相容性粘合剂，在完全固化之前悬浮生物相容性粘合剂的聚合，将生物相容性粘合剂递送至骨缺损，同时聚合基本上悬浮并促进生物相容性粘合剂的聚合以实现完全固化。 该方法提供了具有可延展的骨传导结构的植入的生物相容性粘合剂，而不损害生物相容性粘合剂的物理特性，从而改善骨粘合剂的处理和递送。
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公开(公告)号：US20120046698A1
公开(公告)日：2012-02-23
申请号：US12858585
申请日：2010-08-18
申请人： Eric Kolb , Naresh Akkarapaka , John Boxberger , John Tomich
发明人： Eric Kolb , Naresh Akkarapaka , John Boxberger , John Tomich
IPC分类号： A61B17/86
CPC分类号： A61B17/7032 , A61B17/7098 , A61B17/8625 , A61B17/864 , A61B17/8808 , A61B17/8836
摘要： A pedicle fastener for implantation during a spinal fusion procedure includes a head and shank, the shank being connectable to the head and extending outwardly therefrom. The shank may include a shielding feature formed therein for accommodating an adhesive augmenting the pedicle fastener and improving implantation strength and stiffness thereof. A method for implanting the pedicle fastener includes forming a hole in a pedicle, applying the adhesive to the hole and sliding the shank of the pedicle fastener into the hole. The adhesive may also be applied to the hole through direct injection, injection through a longitudinal cannula formed in the pedicle fastener or by depositing the adhesive on the shank and inserting the shank into the hole. Polymerization of the adhesive may be accelerated by heating the pedicle fastener.
摘要翻译： 脊椎融合术期间用于植入的椎弓根紧固件包括头部和柄部，所述柄部可连接到头部并从其向外延伸。 柄可以包括形成在其中的屏蔽特征，用于容纳增加椎弓根紧固件的粘合剂并提高其植入强度和刚度。 用于植入椎弓根紧固件的方法包括在椎弓根中形成孔，将粘合剂施加到孔并将椎弓根紧固件的柄滑动到孔中。 粘合剂也可以通过直接注射，通过形成在椎弓根紧固件中的纵向插管注射或通过将粘合剂沉积在柄上并将柄插入孔中来施加到孔。 可以通过加热椎弓根紧固件来加速粘合剂的聚合。
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