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公开(公告)号：US5562100A
公开(公告)日：1996-10-08
申请号：US249086
申请日：1994-05-25
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译： 激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导正在研究的组织中的荧光以确定组织的化学组成或病理状况。 激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。 可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。
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2.发明授权公开(公告)号：US06690966B1
公开(公告)日：2004-02-10
申请号：US08107854
申请日：1993-10-22
IPC分类号： A61B500
CPC分类号： A61B5/0086 , A61B5/0071 , A61B5/0075 , A61B5/7203 , A61B5/7257 , A61B2562/0242 , G01N21/65 , G01N2021/656
摘要： Systems and methods for spectroscopic diagnosis and treatment are employed which utilize molecular spectroscopy to accurately diagnose the condition of tissue. Infrared Raman spectroscopy and infrared attenuated total reflectance measurements are performed utilizing a laser radiation source and a fourier transform spectrometer. Information acquired and analyzed in accordance with the invention provides accurate details of biochemical composition and pathologic condition.
摘要翻译： 使用光谱诊断和治疗的系统和方法，其利用分子光谱来准确地诊断组织的状况。 使用激光辐射源和傅立叶变换光谱仪进行红外拉曼光谱和红外衰减全反射率测量。 根据本发明获得和分析的信息提供了生物化学成分和病理状况的准确细节。
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3.发明授权Systems and methods of molecular spectroscopy to provide for the diagnosis of tissue 失效分子光谱学的系统和方法为组织的诊断提供依据公开(公告)号：US06697665B1
公开(公告)日：2004-02-24
申请号：US08288990
申请日：1994-08-11
IPC分类号： A61B600
CPC分类号： A61B5/0086 , A61B5/0071 , A61B5/0075 , A61B5/7203 , A61B5/7257 , A61B2562/0242 , G01N21/65 , G01N2021/656
摘要： Systems and methods for spectroscopic diagnosis and treatment are employed which utilize molecular spectroscopy to accurately diagnose the condition of tissue. Infrared Raman spectrscopy and infrared attenuated total reflectance measurements are performed utilizing a laser radiation source and a fourier transform spectrometer. Information acquired and analyzed in accordance with the invention provides accurate details of biochemical composition and pathologic condition.
摘要翻译： 使用光谱诊断和治疗的系统和方法，其利用分子光谱来准确地诊断组织的状况。 使用激光辐射源和傅立叶变换光谱仪进行红外拉曼光谱和红外衰减全反射率测量。 根据本发明获得和分析的信息提供了生物化学成分和病理状况的准确细节。
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公开(公告)号：US5201318A
公开(公告)日：1993-04-13
申请号：US772620
申请日：1991-10-04
IPC分类号： A61B5/00
CPC分类号： G01J3/4406 , A61B5/0059 , G01N21/6456 , G01N2021/6417 , G01N2021/6419 , G01N2021/6484
摘要： The present invention relates to a method of generating and processing spectral information arising from the laser induced fluorescence of tissue. The intensity of fluorescence is recorded as a function of both excitation and emission wavelengths and contour maps of tissue fluorescence are generated which are useful in the diagnosis of condition of the tissue under examination.
摘要翻译： 本发明涉及一种生成和处理由激光诱导的组织荧光产生的光谱信息的方法。 记录荧光的强度作为激发和发射波长的函数，并且产生组织荧光的轮廓图，其可用于诊断被检组织的状况。
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公开(公告)号：US5419323A
公开(公告)日：1995-05-30
申请号：US720465
申请日：1991-08-29
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译： PCT No.PCT / US89 / 05174 Sec。 371日期：1993年5月7日 102（e）日期1993年5月7日PCT提交1989年11月17日PCT公布。 出版物WO90 / 06718 日期：1990年6月28日。一种激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导研究组织中的荧光以确定组织的化学组成或病理状况。 激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。 可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。
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公开(公告)号：US5345941A
公开(公告)日：1994-09-13
申请号：US24674
申请日：1993-03-01
CPC分类号： G01J3/4406 , A61B5/0059 , G01N21/6456 , G01N2021/6417 , G01N2021/6419 , G01N2021/6484
摘要： The present invention relates to a method of generating and processing spectral information arising from the laser induced fluorescence of tissue. The intensity of fluorescence is recorded as a function of both excitation and emission wavelengths and contour maps of tissue fluorescence are generated which are useful in the diagnosis of condition of the tissue under examination.
摘要翻译： 本发明涉及一种生成和处理由激光诱导的组织荧光产生的光谱信息的方法。 记录荧光的强度作为激发和发射波长的函数，并且产生组织荧光的轮廓图，其可用于诊断被检组织的状况。
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