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    Closure device and methods for making and using them
    5.
    发明授权
    Closure device and methods for making and using them 有权
    关闭装置及其制造和使用的方法

    公开(公告)号：US06719777B2

    公开(公告)日：2004-04-13

    申请号：US09732178

    申请日：2000-12-07

    申请人： Richard S. Ginn ,  William N. Aldrich ,  W. Martin Belef ,  Steven N. Roe

    发明人： Richard S. Ginn ,  William N. Aldrich ,  W. Martin Belef ,  Steven N. Roe

    IPC分类号： A61B1708

    CPC分类号： H03K3/356156 ,  A61B17/0057 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/068 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00668 ,  A61B2017/0641

    摘要： A vascular clip includes a peripheral body defining a plane, and tines extending from the body transversely with respect to the plane, the tines biased towards a planar configuration. The clip includes expandable elements disposed along its periphery that are biased to expand from compressed to expanded states for increasing a diameter of the clip upon deployment. The clip is provided within a housing slidably mounted on an introducer sheath. The sheath is introduced through a puncture into a blood vessel, and after a procedure is performed via the sheath, the housing is advanced into the puncture and the clip deployed until the tines engage tissue adjacent the opening in the vessel wall. The sheath is withdrawn from the patient, leaving the clip in place. The tines at least partially move towards the planar configuration to pull the engaged tissue together and close the opening.

    摘要翻译： 血管夹包括限定平面的周边主体和从身体相对于平面横向延伸的齿，所述尖被偏向平面构型。 夹子包括沿着其周边布置的可膨胀元件，其被偏压以从压缩膨胀到膨胀状态，以在展开时增加夹子的直径。 夹子设置在可滑动地安装在引导器护套上的壳体内。 护套通过穿刺引入血管中，并且在通过护套进行手术之后，将壳体推进到穿刺中并且夹持器展开，直到尖齿与容器壁中的开口相邻的组织接合。 将鞘从病人身上取出，将夹子放在适当位置。 尖齿至少部分地朝向平面构型移动以将被接合的组织拉到一起并关闭开口。

    Apparatus and methods for delivering a vascular closure device to a body lumen
    6.
    发明授权
    Apparatus and methods for delivering a vascular closure device to a body lumen 有权
    用于将血管闭合装置输送到体腔的装置和方法

    公开(公告)号：US06780197B2

    公开(公告)日：2004-08-24

    申请号：US09732835

    申请日：2000-12-07

    申请人： Steven N. Roe ,  Richard S. Ginn ,  W. Martin Belef

    发明人： Steven N. Roe ,  Richard S. Ginn ,  W. Martin Belef

    IPC分类号： A61B1704

    CPC分类号： A61B17/0057 ,  A61B17/064 ,  A61B34/76 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00668 ,  A61B2017/00672

    摘要： An apparatus for delivering a closure element into a puncture communicating with a blood vessel includes an introducer sheath, and a locator member disposed within the sheath, the locator member having a distal portion extending distally beyond the distal end of the sheath. A plurality of splines are provided on the distal portion of the locator member, the splines being selectively expandable between an axial collapsed configuration and a transverse expanded configuration. An actuator is coupled to the locator member for controllably expanding the splines. A housing is slidably disposed on the sheath for deploying a closure element, such as a vascular clip. The locator actuator may automatically collapse the splines upon advancement of the housing.

    摘要翻译： 用于将闭合元件递送到与血管连通的穿刺的装置包括引导器护套和设置在护套内的定位器构件，定位器构件具有向远侧延伸超过护套远端的远端部分。 多个花键设置在定位器构件的远端部分上，该花键可在轴向收缩构型和横向膨胀构型之间选择性地展开。 致动器联接到定位器构件，用于可控地扩展花键。 壳体可滑动地设置在护套上，用于展开闭合元件，例如血管夹。 定位器致动器可以在壳体前进时自动地折叠花键。

    Handheld Medical Diagnostic Devices Housing Lancet Structures
    7.
    发明申请
    Handheld Medical Diagnostic Devices Housing Lancet Structures 审中-公开
    手持式医疗诊断设备住房柳叶刀结构

    公开(公告)号：US20120172757A1

    公开(公告)日：2012-07-05

    申请号：US12981696

    申请日：2010-12-30

    申请人： Steven N. Roe

    发明人： Steven N. Roe

    IPC分类号： A61B5/151

    CPC分类号： A61B5/15182 ,  A61B5/150022 ,  A61B5/150175 ,  A61B5/15019 ,  A61B5/150259 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/15045 ,  A61B5/150458 ,  A61B5/150465 ,  A61B5/150511 ,  A61B5/150572 ,  A61B5/150916 ,  A61B5/150946 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/15132 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/157

    摘要： A lancet housing assembly includes multiple lancets for use in a portable handheld medical diagnostic device for sampling bodily fluids from a skin site of a patient. The lancet housing assembly includes a housing structure comprising multiple lancet compartments. At least one of the lancet compartments includes an outer facing side and an inner facing side. An opening is located at the outer facing side that is arranged and configured to align with a lancet port of the medical diagnostic device. A lancet structure is located in the at least one lancet compartment and comprises a skin penetrating end and a blood transport portion adjacent the skin penetrating end. The lancet structure has (i) an initial configuration where the lancet structure is supported to align the skin penetrating end with the opening to allow the skin penetrating end to extend through the opening and (ii) a retracted configuration where the skin penetrating end moves to a position within the lancet compartment offset from the opening to prevent the lancet structure from extending through the opening.

    摘要翻译： 柳叶刀壳体组件包括用于便携式手持式医疗诊断装置中用于从患者皮肤部位取样体液的多个刺血针。 柳叶刀壳体组件包括包括多个刺血针室的壳体结构。 柳叶刀舱中的至少一个包括外侧和内侧。 开口位于面向外侧的位置，该开口被布置和构造成与医疗诊断装置的刺血针端口对准。 柳叶刀结构位于所述至少一个刺血针室中，并且包括皮肤穿透端和与皮肤穿透端相邻的血液输送部。 柳叶刀结构具有（i）支撑柳叶刀结构以将皮肤穿透端与开口对准以使皮肤穿透端延伸穿过开口的初始构型，以及（ii）皮肤穿透端移动到 刺血针室内的位置偏离开口以防止刺血针结构延伸穿过开口。

    SAMPLING DEVICES AND METHODS UTILIZING BIASED CAPILLARY ACTION
    9.
    发明申请
    SAMPLING DEVICES AND METHODS UTILIZING BIASED CAPILLARY ACTION 审中-公开
    采样设备和使用偏心毛细管动作的方法

    公开(公告)号：US20120065545A1

    公开(公告)日：2012-03-15

    申请号：US13304441

    申请日：2011-11-25

    申请人： Steven N. Roe

    发明人： Steven N. Roe

    IPC分类号： A61B5/00

    CPC分类号： A61B5/150358 ,  A61B5/150022

    摘要： A device is constructed so as to define a capillary channel that draws a body fluid form a proximal portion of the capillary channel toward a distal portion. A counterbore defining a “ledge” not substantially normal to the center line of channel causes the meniscus of body fluid to be “biased” into a non-radially-symmetric shape. In one example, the bias draws the body fluid toward a testing element that is set into a groove in the main body of the device. In another example, hydrophilic and/or hydrophobic regions are created on or in device to produce the biasing effect. In certain configurations, device requires less blood to be drawn into the capillary channel for a successful test than if the biasing effect were not created.

    摘要翻译： 一种装置被构造成限定毛细管通道，该毛细通道从毛细管通道的近端部分朝向远端部分抽取体液。 限定基本上不垂直于通道的中心线的“凸缘”的沉孔引起体液的弯液面被“偏压”成非径向对称的形状。 在一个示例中，偏压将体液朝向设置在装置的主体中的凹槽中的测试元件拉出。 在另一个实例中，在设备上或设备中产生亲水和/或疏水区域以产生偏置效应。 在某些配置中，与没有产生偏置效应相比，设备需要较少的血液被吸入毛细通道才能成功测试。

    Magnetic powered lancing drive
    10.
    发明授权
    Magnetic powered lancing drive 失效
    磁力牵引驱动

    公开(公告)号：US08118824B2

    公开(公告)日：2012-02-21

    申请号：US12211408

    申请日：2008-09-16

    申请人： Steven N. Roe

    发明人： Steven N. Roe

    IPC分类号： A61B17/32

    CPC分类号： A61B5/15194 ,  A61B5/150022 ,  A61B5/150167 ,  A61B5/150183 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/1519

    摘要： A self-powered lancing drive system and lancing technique uses permanent magnets to initially store the potential energy that is converted to kinetic energy for extending a lancet during lancing. This self-powered lancing drive system is a pure permanent magnet drive that is highly reliable under numerous operating conditions. Permanent magnets can produce stronger magnetic fields at smaller sizes as compared to electromagnets. In one form, the lancing system has a drive permanent magnet that is kept fixed or stationary while the lancet magnet travels along the firing path. With the drive magnet being stationary, the lancet experiences fewer fluctuations in the magnetic field. The lancet vibrates less and is driven straighter into the tissue. In another form, a retraction magnet is positioned at the end of the firing path of the lancet, near the tissue, to enhance retraction of the lancet. In another form, a mechanical structure keeps the magnets in close proximity so that the strength of the magnetic propulsion force is maintained. The mechanical structure in one example is a crank mechanism that confines magnet movement to a circular path. The crank mechanism provides a smooth lancing profile as well as facilitates adjustments to the lancing profile.

    摘要翻译： 自动牵引驱动系统和穿刺技术使用永久磁铁来初始储存转换为动能的势能，以便在穿刺期间延长刺血针。 这种自供电的牵引驱动系统是一种纯永磁驱动器，在许多操作条件下都是高度可靠的。 与电磁铁相比，永磁体可以以较小的尺寸产生更强的磁场。 在一种形式中，穿刺系统具有驱动永磁体，其在柳叶刀磁体沿着击发路径行进时保持固定或静止。 在驱动磁体静止的情况下，刺血针的磁场波动较少。 柳叶刀振动较小，并且更直接地驱动到组织中。 在另一种形式中，收缩磁体位于柳叶刀的靠近组织的射击路径的末端，以增强刺血针的收缩。 在另一种形式中，机械结构保持磁体紧密接近，从而保持磁推进力的强度。 一个示例中的机械结构是将磁体运动限制到圆形路径的曲柄机构。 曲柄机构提供平滑的穿刺剖面，并且便于对穿刺剖面进行调整。