Method and apparatus for determining and controlling excess length of a
communications element in a conduit
    1.
    发明授权
    Method and apparatus for determining and controlling excess length of a communications element in a conduit 失效
    用于确定和控制导管中的通信元件的多余长度的方法和装置

    公开(公告)号:US6066275A

    公开(公告)日:2000-05-23

    申请号:US111423

    申请日:1998-07-07

    摘要: A method and apparatus for determining and controlling the excess length of a communications element disposed in a conduit is disclosed. The method includes the steps of measuring the length of a communications element being disposed within the conduit, placing a mark on the conduit each time a pre-determined length of the communications element is disposed within the conduit, and measuring the distance between the marks on the conduit. The excess length is determined by comparing the distance between the initial mark and the subsequent mark on the conduit to the measured length of the communications element disposed within the conduit. To control the excess length ratio, the conduit may be stretched, or process parameters related to formation of the conduit may be changed.

    摘要翻译: 公开了一种用于确定和控制设置在导管中的通信元件的多余长度的方法和装置。 该方法包括以下步骤:测量布置在导管内的通信元件的长度,每当通信元件的预定长度设置在导管内时,在导管上放置标记,并且测量标记之间的距离 导管。 通过将管道上的初始标记和随后标记之间的距离与设置在管道内的通信元件的测量长度进行比较来确定多余长度。 为了控制多余的长度比,导管可以被拉伸,或者可以改变与导管的形成相关的工艺参数。

    NOVEL USE OF AN IL-12 RECEPTOR SPLICE VARIANT AND MOLECULAR ASSAY TO QUANTIFY EXPRESSION THEREOF
    2.
    发明申请
    NOVEL USE OF AN IL-12 RECEPTOR SPLICE VARIANT AND MOLECULAR ASSAY TO QUANTIFY EXPRESSION THEREOF 有权
    IL-12受体基因片段的变化和分子检测的新用途来量化其表达

    公开(公告)号:US20110256158A1

    公开(公告)日:2011-10-20

    申请号:US13022224

    申请日:2011-02-07

    CPC分类号: C07K14/7155

    摘要: The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a vaccine formulation comprising an antigen and IL12Rβ1 isoform 2. In some embodiments, this invention relates to a method of quantifying the ratio of IL12Rβ1 transcript and a splice variant thereof in a sample, including but not limited to at the cDNA level. In other embodiments, this invention relates to a method of augmenting an immune response by administering, inhibiting and/or inducing IL12Rβ1 isoform 2.

    摘要翻译: 本发明描述了用于诊断和治疗应用的组合物。 在一个实施方案中,本发明考虑了包含抗原和IL12R和bgr1同种型2的疫苗制剂。在一些实施方案中,本发明涉及量化样品中IL12R和bgr1转录物及其剪接变体的比例的方法,包括 但不限于cDNA水平。 在其它实施方案中,本发明涉及通过施用,抑制和/或诱导IL12R和bgr1同种型2来增强免疫应答的方法。

    Use of an IL12 receptor-beta 1 splice variant to diagnose active tuberculosis
    3.
    发明授权
    Use of an IL12 receptor-beta 1 splice variant to diagnose active tuberculosis 有权
    使用IL12受体-β1剪接变体来诊断活动性结核病

    公开(公告)号:US08877212B2

    公开(公告)日:2014-11-04

    申请号:US13764289

    申请日:2013-02-11

    IPC分类号: A61K39/04 C12Q1/68 C07H21/04

    摘要: The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a method of identifying an active M. tuberculosis infection. In another embodiment, the present invention contemplates a method of monitoring a M. tuberculosis infection. In yet another embodiment, the present invention contemplates a method of monitoring a patient's response to treatment for an active M. tuberculosis infection. In a further embodiment, the present invention contemplates a method of monitoring a patient's response to treatment for an active M. tuberculosis infection.

    摘要翻译: 本发明描述了用于诊断和治疗应用的组合物。 在一个实施方案中,本发明考虑了鉴定活动性结核分枝杆菌感染的方法。 在另一个实施方案中,本发明考虑了一种监测结核分枝杆菌感染的方法。 在另一个实施方案中,本发明考虑了监测患者对活动性结核分枝杆菌感染的治疗反应的方法。 在另一个实施方案中,本发明考虑了监测患者对活动性结核分枝杆菌感染的治疗反应的方法。

    Optical fiber ribbon
    4.
    发明授权
    Optical fiber ribbon 失效
    光纤带

    公开(公告)号:US06097866A

    公开(公告)日:2000-08-01

    申请号:US71641

    申请日:1998-05-01

    IPC分类号: G02B6/06 G02B6/245 G02B6/44

    摘要: An optical fiber ribbon is disclosed. The optical fiber ribbon comprises a plurality of optical fibers arranged in a parallel planar array, the planar array being further defined by first and second planar sides spanning between first and second ends. A matrix material coating envelops the optical fibers so as to bond the optical fibers together in the parallel planar array. The matrix material coating forms a first substantially planar surface section spanning the first planar side of the planar array of optical fibers. A second substantially planar surface section spans the second planar side of the planar array of optical fibers. A first hinge section bridges the first and second substantially planar surface sections at the first end of the planar array and a second hinge section bridges the first and second substantially planar surface sections at the second end of the planar array. At least one of first hinge sections has a surface portion which extends outwardly normal to and beyond at least one of the planes defined by either the first or second planar surface sections of the matrix material coating. The shapes of the hinge sections enable them to be removed without special tools and enable the ribbons to be stacked. Removal of the hinged sections enables access to the optical fibers without special tools by compromising the structural integrity of the matrix material coating.

    摘要翻译: 公开了一种光纤带。 光纤带包括布置在平行平面阵列中的多个光纤,平面阵列由跨越第一和第二端之间的第一和第二平面侧进一步限定。 矩阵材料涂层包围光纤,以将光纤粘合在平行平面阵列中。 基质材料涂层形成跨越光纤平面阵列的第一平面侧的第一基本平坦的表面部分。 第二基本平坦的表面部分跨越光纤的平面阵列的第二平面侧。 第一铰链部分在平面阵列的第一端处桥接第一和第二基本平坦的表面部分,并且第二铰链部分在平面阵列的第二端处桥接第一和第二基本平坦的表面部分。 第一铰链部分中的至少一个具有表面部分,该表面部分向外延伸到基体材料涂层的第一或第二平坦表面部分所限定的平面中的至少一个以上。 铰链部分的形状使得它们能够在没有特殊工具的情况下被移除,并且可以将带状物堆叠起来。 铰链部分的拆卸可以通过损害基体材料涂层的结构完整性而无需特殊工具就可进入光纤。

    USE OF AN IL12 RECEPTOR-BETA 1 SPLICE VARIANT TO DIAGNOSE ACTIVE TUBERCULOSIS
    6.
    发明申请
    USE OF AN IL12 RECEPTOR-BETA 1 SPLICE VARIANT TO DIAGNOSE ACTIVE TUBERCULOSIS 有权
    使用IL12受体-ATA 1个不同于诊断主动管腔的病例

    公开(公告)号:US20140227324A1

    公开(公告)日:2014-08-14

    申请号:US13764289

    申请日:2013-02-11

    IPC分类号: A61K39/04 C12Q1/68

    摘要: The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a method of identifying an active M. tuberculosis infection. In another embodiment, the present invention contemplates a method of monitoring a M. tuberculosis infection. In yet another embodiment, the present invention contemplates a method of monitoring a patient's response to treatment for an active M. tuberculosis infection. In a further embodiment, the present invention contemplates a method of monitoring a patient's response to treatment for an active M. tuberculosis infection.

    摘要翻译: 本发明描述了用于诊断和治疗应用的组合物。 在一个实施方案中,本发明考虑了鉴定活动性结核分枝杆菌感染的方法。 在另一个实施方案中,本发明考虑了一种监测结核分枝杆菌感染的方法。 在另一个实施方案中,本发明考虑了监测患者对活动性结核分枝杆菌感染的治疗反应的方法。 在另一个实施方案中,本发明考虑了监测患者对活动性结核分枝杆菌感染的治疗反应的方法。

    Use of an IL-12 receptor splice variant and molecular assay to quantify expression thereof
    7.
    发明授权
    Use of an IL-12 receptor splice variant and molecular assay to quantify expression thereof 有权
    使用IL-12受体剪接变体和分子测定来定量其表达

    公开(公告)号:US08394593B2

    公开(公告)日:2013-03-12

    申请号:US13022224

    申请日:2011-02-07

    IPC分类号: C12Q1/68 C07H21/04

    CPC分类号: C07K14/7155

    摘要: The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a vaccine formulation comprising an antigen and IL12Rβ1 isoform 2. In some embodiments, this invention relates to a method of quantifying the ratio of IL12Rβ1 transcript and a splice variant thereof in a sample, including but not limited to at the cDNA level. In other embodiments, this invention relates to a method of augmenting an immune response by administering, inhibiting and/or inducing IL12Rβ1 isoform 2.

    摘要翻译: 本发明描述了用于诊断和治疗应用的组合物。 在一个实施方案中,本发明考虑了包含抗原和IL12R和bgr1同种型2的疫苗制剂。在一些实施方案中,本发明涉及量化样品中IL12R和bgr1转录物及其剪接变体的比例的方法,包括 但不限于cDNA水平。 在其它实施方案中,本发明涉及通过施用,抑制和/或诱导IL12R和bgr1同种型2来增强免疫应答的方法。

    Connector unit for geodesic dome frame strut
    8.
    发明授权
    Connector unit for geodesic dome frame strut 失效
    测地圆顶框架支柱连接单元

    公开(公告)号:US4511278A

    公开(公告)日:1985-04-16

    申请号:US471283

    申请日:1983-03-02

    IPC分类号: E04B1/19 E04B1/32

    摘要: A connector unit for connecting the struts of a geodesic dome framework is disclosed. The connector unit has the general shape of a frustum of a right circular cone. Five equally spaced rectangular depressions are formed in the upper surface of the frustum and a pair of flanges in mirror image relationship in planes perpendicular to the planes of the rectangular depressions are placed on opposite sides of each rectangular depression and each flange of the pair has an opening in its central area with the openings in register with each other.

    摘要翻译: 公开了一种用于连接测地圆顶框架的支柱的连接器单元。 连接器单元具有圆锥形截头锥体的大致形状。 在平截头体的上表面形成五个等间隔的矩形凹陷,并且在垂直于矩形凹陷的平面的平面中的一对在镜像关系中的凸缘被放置在每个矩形凹陷的相对侧上,并且该对的每个凸缘具有 在其中央区域开放,开口彼此对齐。