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    Fluid dose, flow and coagulation sensor for medical instrument
    6.
    发明授权
    Fluid dose, flow and coagulation sensor for medical instrument 失效
    医疗仪器的流体剂量，流量和凝血传感器

    公开(公告)号：US06575017B1

    公开(公告)日：2003-06-10

    申请号：US09724133

    申请日：2000-11-28

    申请人： Gary T. Neel ,  James R. Parker ,  Rick L. Collins ,  David E. Storvick ,  Charles L. Thomeczek, Jr. ,  William J. Murphy ,  George R. Lennert ,  Morris J. Young ,  Daniel L. Kennedy

    发明人： Gary T. Neel ,  James R. Parker ,  Rick L. Collins ,  David E. Storvick ,  Charles L. Thomeczek, Jr. ,  William J. Murphy ,  George R. Lennert ,  Morris J. Young ,  Daniel L. Kennedy

    IPC分类号： G01N2103

    CPC分类号： G01N35/00594 ,  G01N11/06 ,  G01N21/0303 ,  G01N21/0332 ,  G01N21/8483 ,  G01N33/4905 ,  G01N35/00693

    摘要： In combination, an instrument for determining a characteristic of a biological fluid or a control, and a cuvette for holding a sample of the biological fluid or control, the characteristic of which is to be determined. The instrument comprises a radiation-reflective surface, a first source for irradiating the surface, and a first detector for detecting radiation reflected from the surface. The cuvette has two opposed walls substantially transparent to the source radiation and reflected radiation. The first source and first detector are disposed adjacent a first one of the two opposed walls. The radiation reflective surface is disposed adjacent a second of the two opposed walls. A second source is provided for irradiating the surface. The first detector detects radiation from the second source reflected from the surface. The second source is positioned to transmit radiation through the two opposed walls for reflection by the surface and transmission back through the two opposed walls to the first detector to indicate whether a sample has reached a first point in the cuvette.

    摘要翻译： 组合使用用于确定生物流体或对照的特性的仪器，以及用于保持生物流体或对照样品的试管，其特征是确定。 仪器包括辐射反射表面，用于照射表面的第一源和用于检测从表面反射的辐射的第一检测器。 试管具有两个相对的壁，对于源辐射和反射辐射基本上是透明的。 第一源极和第一检测器被布置成与两个相对的壁中的第一个相邻。 辐射反射表面邻近两个相对的壁中的第二个设置。 提供用于照射表面的第二源。 第一检测器检测来自表面反射的第二源的辐射。 第二源被定位成通过两个相对的壁透射辐射，用于通过表面反射并将透射通过两个相对的壁传送到第一检测器，以指示样品是否已经到达比色杯中的第一点。

    Fluid dose, flow and coagulation sensor for medical instrument
    7.
    发明授权
    Fluid dose, flow and coagulation sensor for medical instrument 失效
    医疗仪器的流体剂量，流量和凝血传感器

    公开(公告)号：US5710622A

    公开(公告)日：1998-01-20

    申请号：US478409

    申请日：1995-06-07

    申请人： Gary T. Neel ,  James R. Parker ,  Rick L. Collins ,  David E. Storvick ,  Charles L. Thomeczek, Jr. ,  William J. Murphy ,  George R. Lennert ,  Morris J. Young ,  Daniel L. Kennedy

    发明人： Gary T. Neel ,  James R. Parker ,  Rick L. Collins ,  David E. Storvick ,  Charles L. Thomeczek, Jr. ,  William J. Murphy ,  George R. Lennert ,  Morris J. Young ,  Daniel L. Kennedy

    IPC分类号： G01N11/00 ,  G01N11/06 ,  G01N11/10 ,  G01N21/03 ,  G01N21/05 ,  G01N21/47 ,  G01N21/75 ,  G01N21/86 ,  G01N33/483 ,  G01N33/49 ,  G01N33/86 ,  G01N35/00 ,  G01N33/48

    CPC分类号： G01N35/00594 ,  G01N11/06 ,  G01N21/0303 ,  G01N21/0332 ,  G01N21/8483 ,  G01N33/4905 ,  G01N35/00693

    摘要： A method of immunizing the operation of an instrument which determines a characteristic of a biological fluid or a control against noise. The instrument includes a surface upon which a user deposits a sample of biological fluid or control the characteristic of which is to be determined. The instrument irradiates the sample and detects radiation from the sample to determine the characteristic. The method comprises monitoring the detected radiation a first time to determine if the detected radiation is increasing or decreasing, forming a first change in detected radiation from said first monitoring, subsequently monitoring the detected radiation a second time to determine if the detected radiation is increasing or decreasing, forming a second change in detected radiation from said second monitoring, forming an overall change in detected radiation from the first and second monitorings, establishing a first threshold, establishing a second threshold, comparing the first change to the first threshold, comparing the second change to the first threshold, if the magnitudes of both the first and second changes are greater than the first threshold, comparing the overall change in radiation to the second threshold, and determining the characteristic if the magnitudes of the first and second changes are greater than the first threshold and the overall change is greater than the second threshold.

    摘要翻译： 一种免疫仪器操作的方法，该仪器确定生物流体的特性或对噪声的控制。 仪器包括用户沉积生物流体样品或控制其特性被确定的表面。 仪器照射样品并检测来自样品的辐射，以确定其特性。 该方法包括：首先监测检测到的辐射，以确定检测到的辐射是否在增加或减少，形成来自所述第一监测的检测到的辐射的第一变化，随后第二次监测检测到的辐射，以确定检测到的辐射是否增加， 从所述第二监测中形成检测到的辐射的第二变化，形成来自第一和第二监测的检测到的辐射的总体变化，建立第一阈值，建立第二阈值，将第一变化与第一阈值进行比较， 如果第一和第二变化的幅度大于第一阈值，则将辐射的总体变化与第二阈值进行比较，并且如果第一和第二变化的幅度大于第一阈值，则确定特性 第一个阈值和总体变化大于第二个阈值 阈。

    Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
    9.
    发明授权
    Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control 失效
    用于计算血液样本的血液部分或对照物的凝血特性的方法和装置

    公开(公告)号：US5526111A

    公开(公告)日：1996-06-11

    申请号：US114897

    申请日：1993-08-31

    申请人： Rick L. Collins ,  Martin T. Gerber ,  Zindel H. Heller ,  James L. Maxwell ,  Edna C. Probst ,  Loy M. Vail ,  Stefan Weinert ,  Morris J. Young

    发明人： Rick L. Collins ,  Martin T. Gerber ,  Zindel H. Heller ,  James L. Maxwell ,  Edna C. Probst ,  Loy M. Vail ,  Stefan Weinert ,  Morris J. Young

    IPC分类号： G01N33/86 ,  G01N33/49 ,  G06Q50/00 ,  G06F159/00

    CPC分类号： G01N33/4905 ,  Y10S128/22

    摘要： A method for calculating a coagulation characteristic of a sample of blood, a blood fraction, or a control comprises generating an output signal indicative of coagulation of the sample, sampling the output signal at a sampling rate for a predetermined time to provide a plurality of sampled signal values, storing the sampled signal values, rectifying the stored sampled signal values to provide a plurality of envelope values, and storing the envelope values. The stored envelope values are examined in reverse time order to determine a slope of the envelope at each of the stored envelope values. All relative maxima in the stored envelope values are identified. A range of stored envelope values corresponding to each relative maximum is determined. The identified relative maxima are compared to locate an absolute maximum in the stored envelope values. The coagulation characteristic is then calculated from the stored envelope values within the predetermined range of envelope values corresponding to the absolute maximum.

    摘要翻译： 用于计算血液，血液分数或对照样品的凝固特性的方法包括产生表示样品凝结的输出信号，以采样速率对输出信号进行采样预定时间以提供多个采样 信号值，存储采样的信号值，整理存储的采样信号值以提供多个包络值，以及存储包络值。 以反向时间顺序检查存储的包络值，以确定每个存储的包络值处的包络的斜率。 识别存储的包络值中的所有相对最大值。 确定对应于每个相对最大值的存储包络值的范围。 将所识别的相对最大值进行比较，以确定存储的包络值中的绝对最大值。 然后从对应于绝对最大值的包络值的预定范围内的存储的包络值计算凝结特性。

    Power supply monitor and control for medical instrument
    10.
    发明授权
    Power supply monitor and control for medical instrument 失效
    医疗仪器电源监控

    公开(公告)号：US5886252A

    公开(公告)日：1999-03-23

    申请号：US963672

    申请日：1997-10-31

    申请人： George R. Lennert ,  Rick L. Collins ,  William J. Murphy

    发明人： George R. Lennert ,  Rick L. Collins ,  William J. Murphy

    IPC分类号： A61B5/1459 ,  A61B5/15 ,  G01N21/86 ,  G01N33/483 ,  G01N33/49 ,  G01N35/00 ,  G01N21/03

    CPC分类号： G01N35/00712 ,  G01N21/8483 ,  G01N33/4905 ,  Y10T307/625 ,  Y10T307/735

    摘要： An instrument for determining a characteristic of a biological fluid or a control comprises a radiation-reflective surface, a first source for irradiating the surface, a first detector for detecting radiation reflected from the surface, and a mechanism for determining the characteristic based on the detected radiation. A slide holds a sample of the biological fluid or control the characteristic of which is to be determined. The slide has two opposed walls transparent to the radiation. The first source and first detector are disposed adjacent a first one of the two opposed walls and the radiation reflective surface is disposed adjacent a second of the two opposed walls. A system is provided for supplying power and regulating supplied power from one of multiple power sources to the instrument. The system comprises first and second power sources, first coupling circuitry for selectively coupling the system to the first power source, second coupling circuitry for selectively coupling the system to the second power source, and circuitry for comparing a voltage supplied by the first power source to a voltage supplied by the second power source and for controlling the first coupling circuitry to decouple the system from the first power source when the voltage supplied by the second power source exceeds the voltage supplied by the first power source.

    摘要翻译： 用于确定生物流体或控制物的特征的仪器包括辐射反射表面，用于照射表面的第一源，用于检测从表面反射的辐射的第一检测器，以及用于基于检测到的特性确定特性的机构 辐射。 载玻片保持生物流体的样品或其特性被确定的控制。 滑片具有两个对辐射透明的相对的壁。 第一源极和第一检测器被布置成与两个相对的壁中的第一个相邻，并且辐射反射表面邻近两个相对的壁中的第二个设置。 提供一种用于从多个电源之一向仪器供电和调节供电的系统。 该系统包括第一和第二电源，用于将系统选择性地耦合到第一电源的第一耦合电路，用于将系统选择性地耦合到第二电源的第二耦合电路，以及用于将由第一电源提供的电压与 由第二电源提供的电压，并且当第二电源提供的电压超过由第一电源提供的电压时，用于控制第一耦合电路以将系统与第一电源分离。