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公开(公告)号：US07820705B2
公开(公告)日：2010-10-26
申请号：US11596596
申请日：2005-05-12
Applicant: Robert Epple , Ross Russo , Mihai Azimioara , Yongping Xie
Inventor： Robert Epple , Ross Russo , Mihai Azimioara , Yongping Xie
IPC: C07D413/04 , C07D261/18 , A61K31/4439 , A61K31/422 , A61K31/42
CPC classification number: C07D261/08 , C07D261/18 , C07D413/04
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法，特别是PPAR的活性。
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公开(公告)号：US20070203155A1
公开(公告)日：2007-08-30
申请号：US11597282
申请日：2005-05-24
Applicant: Robert Epple , Christopher Cow , Yongping Xie , Xing Wang , Ross Russo , Mihai Azimioara , Enrique Saez
Inventor： Robert Epple , Christopher Cow , Yongping Xie , Xing Wang , Ross Russo , Mihai Azimioara , Enrique Saez
IPC: A61K31/506 , A61K31/4709 , A61K31/4439 , A61K31/426 , A61K31/427 , C07D417/02
CPC classification number: C07D277/24 , C07D277/16 , C07D277/36 , C07D417/04 , C07D417/14
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法，特别是PPAR的活性。
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公开(公告)号：US20080114044A1
公开(公告)日：2008-05-15
申请号：US11596596
申请日：2005-05-12
Applicant: Robert Epple , Ross Russo , Mihai Azimioara , Yongping Xie
Inventor： Robert Epple , Ross Russo , Mihai Azimioara , Yongping Xie
IPC: A61K31/42 , C07D261/06 , A61P3/10 , A61P9/00
CPC classification number: C07D261/08 , C07D261/18 , C07D413/04
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPAR.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法，特别是PPAR的活性。
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公开(公告)号：US20090192203A1
公开(公告)日：2009-07-30
申请号：US12092962
申请日：2006-11-07
Applicant: Robert Epple , Christopher Cow , Mihai Azimioara , Ross Russo , Yongping Xie , Xing Wang
Inventor： Robert Epple , Christopher Cow , Mihai Azimioara , Ross Russo , Yongping Xie , Xing Wang
IPC: A61K31/426 , C07D263/32 , C07D277/30 , A61K31/421 , A61P25/28
CPC classification number: C07D263/32 , C07D263/46 , C07D277/22 , C07D277/36 , C07D417/12
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法。
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公开(公告)号：US20080292608A1
公开(公告)日：2008-11-27
申请号：US12092254
申请日：2006-11-07
Applicant: Robert Epple , Yongping Xie , Xing Wang , Ross Russo , Christopher Cow , Mihai Azimioara
Inventor： Robert Epple , Yongping Xie , Xing Wang , Ross Russo , Christopher Cow , Mihai Azimioara
IPC: C07D413/04 , C07D417/04 , A61K31/506 , A61K38/45 , A61P3/00 , A61P3/10 , A61P9/00
CPC classification number: C07D413/04
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法。
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Patent Agency Ranking
公开(公告)号：US20100022592A1
公开(公告)日：2010-01-28
申请号：US12527826
申请日：2008-01-07
Applicant: Robert Epple , Mihai Azimioara , Christopher Cow , Ross Russo , Victor Nikulin , Gerald Lelais
Inventor： Robert Epple , Mihai Azimioara , Christopher Cow , Ross Russo , Victor Nikulin , Gerald Lelais
IPC: A61K31/427 , C07D417/10 , C07D417/14 , C12N5/00 , A61K31/454 , A61K31/4439 , A61P3/10
CPC classification number: C07D417/10 , C07D417/14
Abstract: The invention provides compounds of formula (IA) or (IB) and pharmaceutical compositions thereof, which are useful for modulating G protein-coupled receptor 120 (GPR120), and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated GPR120.
Abstract translation: 本发明提供了可用于调节G蛋白偶联受体120（GPR120）的式（IA）或（IB）化合物及其药物组合物，以及使用这些化合物治疗，改善或预防与异常相关的病症的方法 或放松管制的GPR120。
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公开(公告)号：US20090088368A1
公开(公告)日：2009-04-02
申请号：US12160307
申请日：2007-01-25
Applicant: Robert Epple , Ross Russo , Mihai Azimioara
Inventor： Robert Epple , Ross Russo , Mihai Azimioara
IPC: A61K31/437 , C07D513/04 , A61P1/00 , A61P9/00 , A61P35/00 , A61P29/00 , A61P25/00 , A61P11/00 , A61K38/28 , A61K31/60
CPC classification number: C07D513/04
Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.
Abstract translation: 本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法。
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公开(公告)号：US20090137610A1
公开(公告)日：2009-05-28
申请号：US12160302
申请日：2007-01-25
Applicant: Robert Epple , Ross Russo , Mihai Azimioara , Christopher Cow , Valentina Molteni , Xiaolin Li , Donatella Chianelli
Inventor： Robert Epple , Ross Russo , Mihai Azimioara , Christopher Cow , Valentina Molteni , Xiaolin Li , Donatella Chianelli
IPC: A61K31/438 , C07D471/10 , A61K31/506
CPC classification number: C07D471/10
Abstract: The invention provides compounds (Ia), (Ib) and (Ic), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.
Abstract translation: 本发明提供化合物（Ia），（Ib）和（Ic），包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法。
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公开(公告)号：US08394841B2
公开(公告)日：2013-03-12
申请号：US12527849
申请日：2008-01-08
Applicant: Robert Epple , Mihai Azimioara , Christopher Cow , Ross Russo , Victor Nikulin , Gerald Lelais
Inventor： Robert Epple , Mihai Azimioara , Christopher Cow , Ross Russo , Victor Nikulin , Gerald Lelais
IPC: A61K31/426 , A61K31/421 , C07D277/20 , C07D263/30
CPC classification number: C07D263/32 , C07D263/60 , C07D277/30 , C07D513/04
Abstract: The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating G protein-coupled receptor 120 (GPR120), and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated GPR120.
Abstract translation: 本发明提供了可用于调节G蛋白偶联受体120（GPR120）的化合物及其药物组合物，以及使用这些化合物治疗，改善或预防与异常或失调的GPR120相关的病症的方法。
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公开(公告)号：US20100048453A1
公开(公告)日：2010-02-25
申请号：US12092967
申请日：2006-11-07
Applicant: Robert Epple , Christopher N. Cow , Mihai Azimioara , Ross Russo
Inventor： Robert Epple , Christopher N. Cow , Mihai Azimioara , Ross Russo
IPC: A61K38/28 , C07D277/20 , A61K31/426 , A61K38/02 , A61K31/60 , A61P9/00 , A61P3/06 , A61P35/00 , A61P25/00 , A61P1/00
CPC classification number: C07D263/48 , C07D277/42
Abstract: The invention provides compounds (I) pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPARδ.
Abstract translation: 本发明提供化合物（I）包含这些化合物的药物组合物和使用这些化合物治疗或预防与过氧化物酶体增殖物激活受体（PPAR）家族的活性相关的疾病或病症的方法，特别是PPARδ的活性。
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