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公开(公告)号：US5007898A
公开(公告)日：1991-04-16
申请号：US201686
申请日：1988-06-02
IPC分类号： A61M29/02
CPC分类号： A61M29/02 , A61M2025/0004 , A61M2025/1072
摘要： Disclosed is an apparatus and method for the treatment of the symptoms of obstructive prostatism. The apparatus comprises an expandable dilatation catheter and an axially elongate sheath, adapted for transurethral insertion via the external opening of the urethra. The sheath is ellipsoid in cross-section, and provides an initial path through which the catheter and a standard cystoscope lens is guided. Disposed near the proximal end of the expandable dilation portion of the catheter is a plurality of irrigation ports. A saline solution travels through an irrigation conduit and is secreted through the irrigation ports so as to flush away blood, etc., away from the lens of a cystoscope and provides the urologist with an unobstructed view of the dilation catheter and external urethral sphincter muscle. Once the catheter has been properly positioned with respect to both the bladder neck and the sphincter, the dilation balloon may be inflated to force open the affected prostatic urethra and eliminate the obstruction.
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公开(公告)号：US5336208A
公开(公告)日：1994-08-09
申请号：US810845
申请日：1991-12-20
申请人： Robert F. Rosenbluth , Jay A. Lenker , George R. Greene , Rodney A. Brenneman , Patrick A. Maley
发明人： Robert F. Rosenbluth , Jay A. Lenker , George R. Greene , Rodney A. Brenneman , Patrick A. Maley
CPC分类号： A61F13/47209 , A61F2/0009 , A61F5/4401 , A61F5/48 , A61F13/82
摘要： A device for managing urinary incontinence in a human female includes a resilient body resilient adapted to fit between the labia minora and the floor of the vestibule of the vulva, thereby occluding the urethral meatus. An adhesive is applied to the body to provide a sealing engagement with the urethral meatus. In a first embodiment, the body has a base that seats against the floor of the vestibule, and a pair of flexible, lateral flaps that engage the labia minora. A layer of adhesive is applied to the base. A layer of highly-absorbant, hydrophilic material may be situated between the base and the adhesive layer, and/or a layer of scrim material may be so situated. The body may have a longitudinal ridge with a posterior edge having a finger hole to facilitate installation and removal of the device. In a second embodiment, the body is substantially tubular, with the adhesive applied to the exterior surface of the body. In the first and second embodiments, the body is preferably formed of a biodegradable material. In a third embodiment, the body is a flexible bladder or sac, filled with a suitable liquid or gel, that conformingly fits between the labia minora and the floor of the vestibule so as to occlude the urethral meatus. The exterior surface of the bladder is coated with an adhesive to provide a sealing engagement with the meatus. In all embodiments, the preferred adhesive is a mixture of poly 2-hydroxyethyl methacrylate and polyethylene glycol.
摘要翻译： 用于管理人类女性尿失禁的装置包括弹性体，弹性体适于适应阴唇小阴唇和外阴前庭的地板之间，从而封闭尿道口。 将粘合剂施加到身体以提供与尿道口的密封接合。 在第一实施例中，身体具有抵靠前庭地板的基部和与小阴唇接合的一对柔性侧片。 将一层粘合剂施加到基底上。 一层高吸收性亲水材料可以位于基底和粘合剂层之间，和/或一层稀松布材料可以如此定位。 主体可以具有纵向脊，其后边缘具有指孔，以便于装置的安装和拆卸。 在第二实施例中，主体基本上是管状的，其中粘合剂施加到主体的外表面。 在第一和第二实施例中，主体优选地由生物可降解材料形成。 在第三实施例中，身体是柔性膀胱或囊，填充有合适的液体或凝胶，其适形地配合在小阴唇和前庭的地板之间，以封闭尿道口。 膀胱的外表面涂覆有粘合剂以提供与口腔的密封接合。 在所有实施方案中，优选的粘合剂是聚2-羟乙基甲基丙烯酸酯和聚乙二醇的混合物。
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公开(公告)号：US5312430A
公开(公告)日：1994-05-17
申请号：US722899
申请日：1991-06-28
IPC分类号： A61F2/00 , A61F2/06 , A61F2/84 , A61F2/90 , A61K49/00 , A61K51/04 , A61K51/12 , A61M25/10 , A61M29/02 , G01N33/574 , A61M5/00
CPC分类号： A61K51/1206 , A61F2/958 , A61K51/0485 , A61M25/1011 , A61M29/02 , G01N33/57423 , A61F2002/30187 , A61F2002/9583 , A61F2230/0034 , A61K2121/00 , A61K2123/00 , A61M2025/0004 , A61M2025/0008 , A61M2025/1072
摘要： Disclosed is an apparatus and method for the treatment of the symptoms of obstructive prostatism. The apparatus comprises an expandable dilation catheter and preferably an axially elongate sheath, adapted for transurethral insertion via the external opening of the urethra. The sheath is ellipsoid in cross-section, and provides an initial path through which the catheter and a standard cystoscope lens is guided. The dilation catheter or the sheath are provided with a non-radiological locating means for positioning the dilation portion of the catheter with respect to an anatomical landmark. Once the catheter has been properly positioned with respect to both the bladder neck and the sphincter, the dilation balloon may be inflated to force open the affected prostatic urethra and eliminate the obstruction.
摘要翻译： 公开了一种治疗阻塞性前列腺症症状的装置和方法。 该装置包括可膨胀的扩张导管，优选地是轴向细长的护套，适于经由尿道的外部开口经尿道插入。 护套是椭圆形的横截面，并且提供了导管和标准的膀胱镜镜片被引导通过的初始路径。 扩张导管或护套设置有非放射性定位装置，用于相对于解剖学标记定位导管的扩张部分。 一旦导管已经相对于膀胱颈和括约肌适当地定位，则膨胀气球可以被充气以迫使打开受影响的前列腺尿道并消除阻塞。
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公开(公告)号：US5074855A
公开(公告)日：1991-12-24
申请号：US639921
申请日：1991-01-10
CPC分类号： A61F13/47209 , A61F2/0009 , A61F5/4401 , A61F5/48 , A61F13/82
摘要： A device for controlling urinary incontinence in a human female, comprising a resilient pad, configured to seal against and occlude the urethral meatus of the user. The pad includes a base that is adapted to seat against the vestibule of the user's vulva, anteriorly of the vaginal orifice, thereby covering the urethral meatus. An adhesive is provided on the base to seal against and occlude the urethral meatus, and to retain the pad in place against the vestibule. The pad has lateral edges that fit inside the labia minora of the user, to aid in retention of the device. The surface of the pad opposite the base is formed into a longitudinal stiffening ridge that extends into the interlabial space. A handle is attached to the ridge to facilitate removal.
摘要翻译： 一种用于控制人类雌性尿失禁的装置，包括弹性垫，其构造成密封和封闭使用者的尿道口。 该垫包括适于抵靠使用者外阴前庭的阴道的阴前口的底座，从而覆盖尿道口。 在基部上设置粘合剂以密封和封闭尿道口，并将垫保持在与前庭相对的位置。 垫具有适合使用者阴唇内侧的侧边缘，以帮助保持装置。 与基座相对的垫的表面形成为延伸到阴唇间空间的纵向加强脊。 手柄连接到脊以便于移除。
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公开(公告)号：US5030227A
公开(公告)日：1991-07-09
申请号：US360088
申请日：1989-06-01
CPC分类号： A61M25/1011 , A61M29/02 , A61M2025/0004 , A61M2025/1072
摘要： Disclosed is an apparatus and method for the treatment of the symptoms of obstructive prostatism. The apparatus comprises an expandable dilation catheter and preferably an axially elongate sheath, adapted for transurethral insertion via the external opening of the urethra. The sheath is ellipsoid in cross-section, and provides an initial path through which the catheter and a standard cystoscope lens is guided. The dilation catheter or the sheath are provided with a non-radiological locating means for positioning the dilation portion of the catheter with respect to an anatomical landmark. Once the catheter has been properly positioned with respect to both the bladder neck and the sphincter, the dilation balloon may be inflated to force open the affected prostatic urethra and eliminate the obstruction.
摘要翻译： 公开了一种治疗阻塞性前列腺症症状的装置和方法。 该装置包括可膨胀的扩张导管，优选地是轴向细长的护套，适于经由尿道的外部开口经尿道插入。 护套是椭圆形的横截面，并且提供了导管和标准的膀胱镜镜片被引导通过的初始路径。 扩张导管或护套设置有非放射性定位装置，用于相对于解剖学标记定位导管的扩张部分。 一旦导管已经相对于膀胱颈和括约肌适当地定位，则膨胀气球可以被充气以迫使打开受影响的前列腺尿道并消除阻塞。
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公开(公告)号：US5527336A
公开(公告)日：1996-06-18
申请号：US398049
申请日：1995-03-02
CPC分类号： A61F2/958 , A61M25/1011 , A61M29/02 , A61F2002/30187 , A61F2002/9583 , A61F2230/0034 , A61M2025/0004 , A61M2025/1072
摘要： Disclosed is an apparatus and method for the treatment of the symptoms of obstructive prostatism. The apparatus comprises an expandable dilation catheter and preferably an axially elongate sheath, adapted for transurethral insertion via the external opening of the urethra. The sheath is ellipsoid in cross-section, and provides an initial path through which the catheter and a standard cystoscope lens is guided. The dilation catheter or the sheath are provided with a non-radiological locating means for positioning the dilation portion of the catheter with respect to an anatomical landmark. Once the catheter has been properly positioned with respect to both the bladder neck and the sphincter, the dilation balloon may be inflated to force open the affected prostatic urethra and eliminate the obstruction.
摘要翻译： 公开了一种治疗阻塞性前列腺症症状的装置和方法。 该装置包括可膨胀的扩张导管，优选地是轴向细长的护套，适于经由尿道的外部开口经尿道插入。 护套是椭圆形的横截面，并且提供了导管和标准的膀胱镜镜片被引导通过的初始路径。 扩张导管或护套设置有非放射性定位装置，用于相对于解剖学标记定位导管的扩张部分。 一旦导管已经相对于膀胱颈和括约肌适当地定位，则膨胀气球可以被充气以迫使打开受影响的前列腺尿道并消除阻塞。
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7.发明授权
公开(公告)号：US5002558A
公开(公告)日：1991-03-26
申请号：US397579
申请日：1989-08-23
CPC分类号： A61M29/02 , A61M25/1002 , A61M2025/1068
摘要： A urethral catheter having an adjustable dilating balloon length for dilating a prostatic urethra and a method for using same. The device includes a catheter to which a Foley balloon is affixed at the distal end, and to which a dilating balloon is annularly affixed, and includes means to independently expand and contract the balloons. Concentrically encompassing the catheter is a sheath or ring, which in one embodiment slides along the outside of the catheter. With the method of the present invention, the affected prostatic urethra is measured using a cystoscope and a calibrated catheter or other known measurement means. The sheath of an adjustable catheter of one embodiment of the present invention is set to the measured length by covering a portion of the dilating balloon with the sheath. The dilating catheter is inserted through the urethra until the balloon at the distal end is located within the bladder, at which point it is inflated and the dilating catheter is anchored in position. Then the dilating balloon is inflated to force the prostate away from the urethra. The dilating balloon may be left in place for periods of up to an hour or more to optimize the dilation effect, at which point the balloons are deflated and the dilating catheter is removed. With a further embodiment, the length of the dilating balloon is adjusted by severing portions of an adjustable length sheath to expose the length of balloon desired.
摘要翻译： 具有用于扩张前列腺尿道的可调节扩张球囊长度的尿道导管及其使用方法。 该装置包括导管，其中Foley气球被固定在远端，并且扩张气囊环形固定到该导管，并且包括用于独立地膨胀和收缩气囊的装置。 集中包围导管是护套或环，其在一个实施例中沿着导管的外部滑动。 利用本发明的方法，使用膀胱镜和校准的导管或其他已知的测量手段来测量受影响的前列腺尿道。 通过用护套覆盖一部分扩张球囊，将本发明的一个实施例的可调节导管的护套设定为测量的长度。 扩张导管穿过尿道插入，直到远端的球囊位于膀胱内，此时充气，扩张导管固定在适当的位置。 然后扩张气囊被充气以迫使前列腺远离尿道。 扩张气球可以留在适当位置达一个小时或更长的时间以优化扩张效果，此时气囊被放气并且扩张导管被去除。 在另一个实施例中，通过切断可调节长度护套的部分来调节扩张气囊的长度以暴露所需球囊的长度。
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公开(公告)号：US4388735A
公开(公告)日：1983-06-21
申请号：US203804
申请日：1980-11-03
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0075 , Y10S623/90
摘要： Prosthetic heart valves comprising an annular, right cylindrical, metal stent covered with fabric to which a glutaraldehyde-stabilized pericardial valving element formed of three leaflets, each having a plateau on a truncated triangle extending higher at the center than at the edges, and formed as a cylinder having a diameter substantially equal to the diameter of the stent, and having a low profile is disclosed.
摘要翻译： 假体心脏瓣膜包括用织物覆盖的环形的右圆柱形金属支架，戊二醛稳定的心包瓣元件由三个小叶形成，每个叶片在中心处比在边缘处更高的截顶三角形，并形成为 公开了具有基本上等于支架直径的直径并且具有低轮廓的圆柱体。
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公开(公告)号：US4441216A
公开(公告)日：1984-04-10
申请号：US327081
申请日：1981-12-03
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2220/0075 , Y10S623/90
摘要： An improved stent for prosthetic tissue heart valves having upright legs which have radiused upper tips which are approximately one-half the width of prior art stent legs is disclosed. These narrow tipped stent legs reduce stress induced in the leaflets by curvature of the leaflets around the tips of the stent legs in the closed position, extending the service life of the valve. Tabs are added to the tips of the stent legs to add structural strength. These tabs can be tapered or straight but their bottom portions must be narrower than the stent leg. The tabs have a plurality of holes in them through which coaptation stitches are passed. The coaptation stitch can be two separate stitches, one in a first plane and one in a second plane at 90.degree. to the first plane, or, in the preferred embodiment, a single figure eight stitch passing through the holes in the tab in a plane coincident with the long axis of the stent leg.
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公开(公告)号：US07483558B2
公开(公告)日：2009-01-27
申请号：US11733697
申请日：2007-04-10
CPC分类号： A61L31/146 , A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B17/1219 , A61B34/10 , A61B2017/00526 , A61B2017/1205 , A61F2/06 , A61L31/145 , A61L31/18 , A61L2430/36 , B33Y50/00 , B33Y80/00 , Y10S623/901 , Y10S623/903 , Y10T29/49
摘要： A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. A retention element is contained within the microcatheter and has a distal end detachably connected to the implant. A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site.
摘要翻译： 由可压缩泡沫材料形成的血管植入物具有压缩构型，其可膨胀到基本上符合要栓塞的血管部位的形状和尺寸的构造。 优选地，植入物由亲水的大孔泡沫材料形成，具有血管部位的缩小模型的初始构型，从而可压缩成压缩构型。 通过扫描血管部位来创建植入物以产生数字化的扫描数据集; 使用扫描数据集创建血管部位的三维数字化虚拟模型; 使用虚拟模型创建血管部位的缩小物理模具; 并使用模具以血管部位的缩小模型的形式产生血管植入物。 为了栓塞血管部位，植入物被压缩并通过微导管，其远端已经进入血管部位。 在进入血管部位时，植入物基本上扩张以填充血管部位。 保持元件容纳在微导管内并且具有可拆卸地连接到植入物的远端。 使用柔性的管状展开元件将植入物和保持元件通过微导管，然后当植入物从微导管通过并进入血管部位时，将植入物与保留元件分离。
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