公开(公告)号：US07653434B1

公开(公告)日：2010-01-26

申请号：US10913942

申请日：2004-08-05

申请人： Robert G. Turcott ,  Michael K. Fang ,  Timothy A. Fayram

发明人： Robert G. Turcott ,  Michael K. Fang ,  Timothy A. Fayram

IPC分类号： A61N1/39

CPC分类号： A61N1/375 ,  A61B5/0031 ,  A61N1/025 ,  A61N1/36514 ,  A61N1/3702 ,  A61N1/3962

摘要： Embodiments of the present invention relate to implantable sensors for obtaining hemodynamic data and/or physiologic data. More specifically, embodiments of the present invention enable additional sensing hardware to be added into implantable devices more quickly and less expensively. Additionally, embodiments of the present invention enable such adding of additional sensing hardware with little or no effect on the conventional functions of the implantable device to which the sensor hardware is being added.

摘要翻译： 本发明的实施例涉及用于获得血液动力学数据和/或生理数据的可植入传感器。 更具体地，本发明的实施例使得能够更快速且更低成本地将附加感测硬件添加到可植入设备中。 此外，本发明的实施例使得能够对附加传感器硬件的可植入装置的常规功能几乎没有或没有影响的附加感测硬件的添加。

公开(公告)号：US20110201946A1

公开(公告)日：2011-08-18

申请号：US13028133

申请日：2011-02-15

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/024

CPC分类号： A61B5/1455 ,  A61B2560/0209

摘要： Methods, systems and devices are provided for reducing the amount of data, processing and/or power required to analyze hemodynamic signals such as photoplethysmography (PPG) signals, pressure signals, and impedance signals. In response to detecting a specific event associated with a cyclical body function, a hemodynamic signal is continuously sampled during a window following the detecting of the specific event, wherein the window is shorter than a cycle associated with the cyclical body function. The hemodynamic signal is then analyzed based on the plurality of samples. This description is not intended to be a complete description of, or limit the scope of, the invention. Other features, aspects, and objects of the invention can be obtained from a review of the specification, the figures, and the claims.

摘要翻译： 提供了方法，系统和设备，用于减少分析血流动力学信号（如光电体积描记术（PPG）信号，压力信号和阻抗信号）所需的数据量，处理和/或功率。 响应于检测到与周期性身体功能相关联的特定事件，在检测到特定事件之后的窗口期间连续采样血液动力学信号，其中窗口比与周期性身体功能相关联的周期短。 然后基于多个样本分析血液动力学信号。 本说明书不是对本发明的完整描述或限制本发明的范围。 本发明的其它特征，方面和目的可以通过对说明书，附图和权利要求的评述来获得。

公开(公告)号：US07909768B1

公开(公告)日：2011-03-22

申请号：US10894962

申请日：2004-07-19

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61B5/00

CPC分类号： A61B5/1455 ,  A61B2560/0209

摘要： Methods, systems and devices are provided for reducing the amount of data, processing and/or power required to analyze hemodynamic signals such as photoplethysmography (PPG) signals, pressure signals, and impedance signals. In response to detecting a specific event associated with a cyclical body function, a hemodynamic signal is continuously sampled during a window following the detecting of the specific event, wherein the window is shorter than a cycle associated with the cyclical body function. The hemodynamic signal is then analyzed based on the plurality of samples.

摘要翻译： 提供了方法，系统和设备，用于减少分析血流动力学信号（如光电体积描记术（PPG）信号，压力信号和阻抗信号）所需的数据量，处理和/或功率。 响应于检测到与周期性身体功能相关联的特定事件，在检测到特定事件之后的窗口期间连续采样血液动力学信号，其中窗口比与周期性身体功能相关联的周期短。 然后基于多个样本分析血液动力学信号。

公开(公告)号：US07130689B1

公开(公告)日：2006-10-31

申请号：US10816629

申请日：2004-04-01

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61N1/18

CPC分类号： A61N1/36514 ,  A61N1/3627 ,  A61N1/36542 ,  A61N1/3655 ,  A61N1/3682

摘要： Methods and systems for performing pacing interval optimization are provided. One or more optimum pacing interval is determined for each of a plurality of different ranges of heart rate, different levels of autonomic tone, different body temperature ranges, or combinations thereof. The information (e.g., measures of hemodynamic response) collected to perform pacing interval optimization can be collected and stored in a table over disjoint periods of time. Such measures of hemodynamic performance are preferably relative measures, but can alternatively be absolute measures.

摘要翻译： 提供了用于执行起搏间隔优化的方法和系统。 针对多个不同范围的心率，不同水平的自主音，不同体温范围或其组合中的每一个确定一个或多个最佳起搏间隔。 收集以执行起搏间期优化的信息（例如，血液动力学响应的测量）可以在不相交的时间段内收集并存储在表中。 血液动力学性能的这种措施优选地是相对措施，但也可以是绝对措施。

公开(公告)号：US07690378B1

公开(公告)日：2010-04-06

申请号：US10897372

申请日：2004-07-21

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： F16K31/02

CPC分类号： A61B5/0816 ,  A61B5/14551 ,  A61B5/411 ,  A61B5/415 ,  A61B5/4818

摘要： Methods, systems and devices are provided for monitoring respiratory disorders based on monitored factors of a photoplethysmography (PPG) signal that is representative of peripheral blood volume. The monitored factors can be respiratory effort as well as respiratory rate and/or blood oxygen saturation level. The systems and devices may or may not be implanted in a patient.

摘要翻译： 提供方法，系统和装置，用于监测代表外周血容量的光电容积描记术（PPG）信号的监测因素来监测呼吸系统疾病。 监测的因素可以是呼吸功能以及呼吸频率和/或血氧饱和度水平。 系统和装置可以植入或不植入患者体内。

公开(公告)号：US07364550B1

公开(公告)日：2008-04-29

申请号：US10872165

申请日：2004-06-17

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61B5/02 ,  A61B5/0295

CPC分类号： A61N1/3702 ,  A61N1/36514 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3925 ,  A61N1/3962

摘要： A method and device, such as an implantable cardiac device, for motion and noise immunity in hemodynamic measurement is presented. The method includes obtaining a template waveform representing hemodynamic performance of a heart during a first hemodynamic state and obtaining an autocharacterization measure from an autocharacterization (e.g., autocorrelation) of the template waveform. The method further includes obtaining a test waveform during a second hemodynamic state, performing a cross-characterization (e.g., cross-correlation) of the template waveform and test waveform to identify a cross-characterization measure, and comparing the autocharacterization measure with the cross-characterization measure as a measurement of hemodynamic status of the second hemodynamic state. The device includes hardware and/or software for performing the described method.

摘要翻译： 提出了一种用于血流动力学测量中的运动和噪声免疫的方法和装置，例如可植入心脏装置。 该方法包括获得表示第一血液动力学状态期间心脏的血流动力学性能的模板波形，并从模板波形的自动特征（例如，自相关）获得自动特征测量。 该方法还包括在第二血液动力学状态期间获得测试波形，执行模板波形和测试波形的交叉表征（例如，互相关）以识别交叉表征测量，并将自动特征测量与交叉表征测量进行比较， 表征测量作为第二血流动力学状态的血液动力学状态的测量。 该设备包括用于执行所述方法的硬件和/或软件。

公开(公告)号：US07212861B1

公开(公告)日：2007-05-01

申请号：US10838939

申请日：2004-05-03

申请人： Euljoon Park ,  Gene A. Bornzin ,  Robert G. Turcott

发明人： Euljoon Park ,  Gene A. Bornzin ,  Robert G. Turcott

IPC分类号： A61N1/00

CPC分类号： A61N1/36585 ,  A61N1/3627

摘要： An implantable cardiac stimulation device is configured to measure selected ventricular contraction parameters and possibly apply stimulation therapy based on the ventricular contraction parameters. In accordance with one aspect, the ventricular contraction parameters include impedance values that correspond to the volume of fluid in the right ventricle and the left ventricle. In accordance with another aspect, the ventricular contraction parameters include motion values that correspond to heart sounds/motion in the right ventricle and the left ventricle. The ventricular contraction parameters can be used to form pseudo P-V loop from which treatment decisions can be made.

摘要翻译： 可植入心脏刺激装置被配置为测量所选择的心室收缩参数，并且可以基于心室收缩参数应用刺激治疗。 根据一个方面，心室收缩参数包括对应于右心室和左心室中的流体体积的阻抗值。 根据另一方面，心室收缩参数包括对应于右心室和左心室中的心音/运动的运动值。 心室收缩参数可用于形成伪P-V循环，从中可以进行治疗决定。

公开(公告)号：US09022030B2

公开(公告)日：2015-05-05

申请号：US12709336

申请日：2010-02-19

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： F16K31/02 ,  A61B5/08 ,  A61B5/1455 ,  A61B5/00

CPC分类号： A61B5/0816 ,  A61B5/14551 ,  A61B5/411 ,  A61B5/415 ,  A61B5/4818

摘要： Methods, systems and devices are provided for monitoring respiratory disorders based on monitored factors of a photoplethysmography (PPG) signal that is representative of peripheral blood volume. The monitored factors can be respiratory effort as well as respiratory rate and/or blood oxygen saturation level. The systems and devices may or may not be implanted in a patient.

摘要翻译： 提供方法，系统和装置，用于监测代表外周血容量的光电容积描记术（PPG）信号的监测因素来监测呼吸系统疾病。 监测的因素可以是呼吸功能以及呼吸频率和/或血氧饱和度水平。 系统和装置可以植入或不植入患者体内。

公开(公告)号：US08617080B2

公开(公告)日：2013-12-31

申请号：US13028133

申请日：2011-02-15

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61B5/02 ,  A61B5/08

CPC分类号： A61B5/1455 ,  A61B2560/0209

摘要： Methods, systems and devices are provided for reducing the amount of data, processing and/or power required to analyze hemodynamic signals such as photoplethysmography (PPG) signals, pressure signals, and impedance signals. In response to detecting a specific event associated with a cyclical body function, a hemodynamic signal is continuously sampled during a window following the detecting of the specific event, wherein the window is shorter than a cycle associated with the cyclical body function. The hemodynamic signal is then analyzed based on the plurality of samples. This description is not intended to be a complete description of, or limit the scope of, the invention. Other features, aspects, and objects of the invention can be obtained from a review of the specification, the figures, and the claims.

摘要翻译： 提供了方法，系统和设备，用于减少分析血流动力学信号（如光电体积描记术（PPG）信号，压力信号和阻抗信号）所需的数据量，处理和/或功率。 响应于检测到与周期性身体功能相关联的特定事件，在检测到特定事件之后的窗口期间连续采样血液动力学信号，其中窗口比与周期性身体功能相关联的周期短。 然后基于多个样本分析血液动力学信号。 本说明书不是对本发明的完整描述或限制本发明的范围。 本发明的其它特征，方面和目的可以通过对说明书，附图和权利要求的评述来获得。

公开(公告)号：US07494470B1

公开(公告)日：2009-02-24

申请号：US10938173

申请日：2004-09-10

申请人： Robert G. Turcott

发明人： Robert G. Turcott

IPC分类号： A61B5/00

CPC分类号： A61N1/36557 ,  A61B5/14542 ,  A61B5/1459

摘要： Analysis of metabolic gases by an implantable medical device allows the assessment of the status of a congestive heart failure patient by providing for the assessment of cardiac output. The present invention is directed to an implanted medical device configured to measure concentrations of metabolic gases in the blood to determine cardiac output of a patient. The device is also configured to measure changes in the cardiac output of a patient. The present invention is also directed to a method of measuring cardiac output by an implanted medical device. Further, the detection of changes in cardiac output utilizing an implanted medical device as disclosed herein is useful in a method of detecting exacerbation of congestive heart failure. The implanted medical device can also be used to pace a heart to modify cardiac output in a patient.

摘要翻译： 通过可植入医疗设备分析代谢气体允许通过提供心输出量的评估来评估充血性心力衰竭患者的状态。 本发明涉及一种植入式医疗装置，其被配置为测量血液中代谢气体的浓度以确定患者的心输出量。 该装置还被配置为测量患者的心输出量的变化。 本发明还涉及一种通过植入式医疗装置测量心输出量的方法。 此外，利用本文公开的植入式医疗装置检测心输出量的变化对于检测充血性心力衰竭恶化的方法是有用的。 植入的医疗装置还可以用于调整心脏以改善患者的心输出量。