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68 条记录 (耗时 0.025 秒)

    Anti-Hypercholesterolemic Compounds
    1.
    发明申请
    Anti-Hypercholesterolemic Compounds 审中-公开
    抗高胆固醇血症化合物

    公开(公告)号：US20090137546A1

    公开(公告)日：2009-05-28

    申请号：US11992990

    申请日：2006-09-29

    申请人： Robert J. DeVita ,  Gregori J. Morriello ,  Peter Lin

    发明人： Robert J. DeVita ,  Gregori J. Morriello ,  Peter Lin

    IPC分类号： A61K31/397 ,  C07D205/08

    CPC分类号： C07D205/08 ,  C07D405/10

    摘要： This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.

    摘要翻译： 本发明提供式I的胆固醇吸收抑制剂及其药学上可接受的盐和酯。 该化合物可用于降低血浆胆固醇水平，特别是低密度脂蛋白胆固醇，以及用于治疗和预防动脉粥样硬化和动脉粥样硬化疾病事件。

    ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS
    2.
    发明申请
    ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS 审中-公开
    抗高血压药物化合物

    公开(公告)号：US20100035857A1

    公开(公告)日：2010-02-11

    申请号：US12518771

    申请日：2007-12-14

    申请人： Robert J. DeVita ,  Gregori J. Morriello ,  Peter Lin

    发明人： Robert J. DeVita ,  Gregori J. Morriello ,  Peter Lin

    IPC分类号： A61K31/397 ,  C07D205/08 ,  A61P7/00

    CPC分类号： C07D205/08 ,  C07H15/00

    摘要： This invention provides cholesterol absorption inhibitors of Formula I:I and the pharmaceutically acceptable salts thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.

    摘要翻译： 本发明提供式I的I型胆固醇吸收抑制剂及其药学上可接受的盐。 该化合物可用于降低血浆胆固醇水平，特别是低密度脂蛋白胆固醇，以及用于治疗和预防动脉粥样硬化和动脉粥样硬化疾病事件。

    2-Aminoquinoline compounds
    5.
    发明授权
    2-Aminoquinoline compounds 失效
    2-氨基喹啉化合物

    公开(公告)号：US07084156B2

    公开(公告)日：2006-08-01

    申请号：US10496615

    申请日：2002-11-22

    申请人： Robert J. DeVita ,  Lehua Chang ,  Danny Chaung ,  MyLe Hoang ,  JinLong Jiang ,  Peter Lin ,  Andreas W. Sailer ,  Jonathan R. Young

    发明人： Robert J. DeVita ,  Lehua Chang ,  Danny Chaung ,  MyLe Hoang ,  JinLong Jiang ,  Peter Lin ,  Andreas W. Sailer ,  Jonathan R. Young

    IPC分类号： C07D215/38 ,  C07D215/16 ,  A61K31/47

    CPC分类号： C07D215/227 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D491/04 ,  C07D495/10

    摘要： The present invention is concerned with compounds of the general Formula I: and pharmaceutically acceptable salts thereof, which are useful as melanin concentrating hormone receptor antagonists, particularly MCH-1R antagonists. As such, compounds of the present invention are useful for the treatment or prevention of obesity or eating disorders associated with excessive food intake and complications thereof, osteoarthritis, certain cancers, AIDS wasting, cachexia, frailty (particularly in elderly), mental disorders stress, cognitive disorders, sexual function, reproductive function, kidney function, locomotor disorders, attention deficit disorder (ADD), substance abuse disorders and dyskinesias, Huntington's disease, epilepsy, memory function, and spinal muscular atrophy. Compounds of formula I may therefore be used in the treatment of these conditions, and in the manufacture of a medicament useful in treating these conditions. Pharmaceutical formulations comprising one of the compounds of formula (I) as an active ingredient are disclosed, as are processes for preparing these compounds.

    摘要翻译： 本发明涉及通式I的化合物及其药学上可接受的盐，其可用作黑色素浓缩激素受体拮抗剂，特别是MCH-1R拮抗剂。 因此，本发明的化合物可用于治疗或预防与食物过量摄取及其并发症，骨关节炎，某些癌症，艾滋病消瘦，恶病质，虚弱（特别是老年人）相关的肥胖或进食障碍，精神障碍压力， 认知障碍，性功能，生殖功能，肾功能，运动障碍，注意力缺陷障碍（ADD），药物滥用障碍和运动障碍，亨廷顿病，癫痫，记忆功能和脊髓性肌肉萎缩。 因此，式I化合物可用于治疗这些病症，以及制备用于治疗这些病症的药物。 作为制备这些化合物的方法，公开了包含式（I）化合物之一作为活性成分的药物制剂。

    Office Chair Foot Base
    6.
    发明申请
    Office Chair Foot Base 审中-公开
    办公椅脚座

    公开(公告)号：US20130062495A1

    公开(公告)日：2013-03-14

    申请号：US13230938

    申请日：2011-09-13

    申请人： Peter Lin

    发明人： Peter Lin

    IPC分类号： A47C7/62

    CPC分类号： A47C7/004

    摘要： An office chair foot base providing to support an office chair has a top end disposed towards the office chair, and a bottom end disposed opposite to the top end towards the ground. The office chair foot base comprises a main boy and a plurality of legs. The main boy includes an interior wall formed circularly and a connecting portion connecting to the interior wall at the bottom end. The plurality of legs formed radially extending opposite to the interior wall to a radial extent. Each of the plurality of legs includes a joining portion formed at the bottom end. The joining portion connects with the connecting portion.

    摘要翻译： 提供用于支撑办公椅的办公椅脚座具有朝向办公椅放置的顶端，以及与顶端朝向地面相对设置的底端。 办公椅脚座包括一个主男孩和多个腿。 主要男孩包括圆形的内壁和连接到底端的内壁的连接部分。 所述多个支腿沿径向延伸形成为径向向内延伸。 多个腿中的每一个包括形成在底端的接合部。 连接部分与连接部分连接。

    Chair
    7.
    发明申请
    Chair 失效
    椅子

    公开(公告)号：US20120025575A1

    公开(公告)日：2012-02-02

    申请号：US12899711

    申请日：2010-10-07

    申请人： Peter Lin

    发明人： Peter Lin

    IPC分类号： A47C1/024

    CPC分类号： A47C1/026 ,  A47C3/34 ,  A47C7/462

    摘要： A chair includes a supporting structure, a seat moveably mounted on the supporting structure and being moveable with respect to the supporting structure in a vertical direction, and a backrest including a first frame pivotally connected to the seat and a second frame separate from and pivotally mounted on the first frame so as to connect to the seat. Further, a first control device is mounted and concealed between the first and second frames in order to prevent the user from inadvertently colliding with it. The first control device is adjusted for various relative pivotal positions of first and second frames.

    摘要翻译： 座椅包括支撑结构，可移动地安装在支撑结构上并且可相对于支撑结构在垂直方向上移动的座椅，以及靠背，其包括枢转地连接到座椅的第一框架和与之枢转地安装的第二框架 在第一个框架上，以便连接到座椅。 此外，第一控制装置安装并隐藏在第一和第二框架之间，以防止用户与其无意地碰撞。 第一控制装置针对第一和第二框架的各种相对枢转位置进行调节。

    Container and rack system
    10.
    发明授权
    Container and rack system 有权
    集装箱和货架系统

    公开(公告)号：US07469792B1

    公开(公告)日：2008-12-30

    申请号：US10968409

    申请日：2004-10-18

    申请人： Peter Lin

    发明人： Peter Lin

    IPC分类号： A47B73/00

    CPC分类号： A47B73/002 ,  A47B73/004 ,  A61L2/07 ,  A61L2/26

    摘要： A rack and container assembly and the associated method of holding the containers in the rack. The rack has frame elements that define at least one slot of a first width. The frame elements are rounded in cross-section having a first radius of curvature. Each of the containers has an exterior surface of a second width that is greater than the width of the slots in the rack. An arcuate groove is formed in the exterior surface of each container. The arcuate grooves enable the containers to pass into the slots. Each arcuate groove has a cross-section with a second radius of curvature that is at least as large as the first radius of curvature of the frame elements that form the slot. When the containers are placed in the slots, the only area of the containers that physically contacts the rack is the shallow area of the arcuate groove.

    摘要翻译： 机架和容器组件以及将容器保持在机架中的相关方法。 齿条具有限定第一宽度的至少一个槽的框架元件。 框架元件具有第一曲率半径的横截面为圆形。 每个容器具有大于齿条中的槽的宽度的第二宽度的外表面。 在每个容器的外表面上形成弓形槽。 弓形凹槽使得容器能够进入槽中。 每个弧形凹槽具有至少与构成槽的框架元件的第一曲率半径一样大的第二曲率半径的横截面。 当容器放置在槽中时，物理接触机架的容器的唯一区域是弓形槽的浅区域。