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    Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists
    3.
    发明授权
    Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists 失效
    八氢吡喃[3,4-C]吡咯速激肽受体拮抗剂

    公开(公告)号：US07652058B2

    公开(公告)日：2010-01-26

    申请号：US11792514

    申请日：2005-12-12

    申请人： Robert J. DeVita ,  Jinlong Jiang ,  Sander G. Mills ,  Jonathan R. Young

    发明人： Robert J. DeVita ,  Jinlong Jiang ,  Sander G. Mills ,  Jonathan R. Young

    IPC分类号： A61K31/407 ,  C07D491/052

    CPC分类号： C07D491/04

    摘要： The present invention is directed to certain hydropyranopyrrolidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.

    摘要翻译： 本发明涉及可用作神经激肽-1（NK-1）受体拮抗剂，速激肽抑制剂，特别是物质P的某些氢吡喃并吡咯烷化合物。本发明还涉及包含这些化合物作为活性成分的药物组合物和 使用化合物及其制剂治疗某些疾病，包括呕吐，尿失禁，抑郁和焦虑。

    Pressure sequence controlled valve and sprinkler system using same
    6.
    发明授权
    Pressure sequence controlled valve and sprinkler system using same 失效
    压力顺序控制阀和喷淋系统使用它

    公开(公告)号：US06622933B1

    公开(公告)日：2003-09-23

    申请号：US09855123

    申请日：2001-05-14

    申请人： George A. Young ,  Jonathan R. Young

    发明人： George A. Young ,  Jonathan R. Young

    IPC分类号： A01G2502

    CPC分类号： A01G25/02 ,  Y10T137/86413 ,  Y10T137/86445

    摘要： A lawn sprinkler system utilizes a master controller whose input is coupled to a water supply and whose output is coupled via pipe to a number of valves. The master controller is preprogrammed to supply water for a number of phases of operation, where the operation advances to a subsequent phase upon turning the supply of water off for a relatively short amount of time followed by turning the supply of water back on. Each of the valves includes an in-port and an out-port, where each valve cycles through each of the phases as controlled by the master controller. Each valve is setable/changeable to supply water to its respective out-port during a selected phase of operation.

    摘要翻译： 草坪洒水系统利用主控制器，其输入端与水源相连，其输出通过管道耦合到多个阀门。 主控制器被预编程为多个操作阶段的水供水，其中在相当短的时间内关闭水源后，操作进入后续阶段，然后重新打开供水。 每个阀都包括入口和出口，每个阀循环通过主控制器控制的每个相。 每个阀门可设置/更换，以在选定的操作阶段向其各自的出口供水。

    Construction for an automotive vehicle
    10.
    发明授权
    Construction for an automotive vehicle 有权
    汽车的建造

    公开(公告)号：US08292353B2

    公开(公告)日：2012-10-23

    申请号：US12628599

    申请日：2009-12-01

    申请人： Toro Ishimaru ,  Jonathan R. Young ,  Robert D. Smith

    发明人： Toro Ishimaru ,  Jonathan R. Young ,  Robert D. Smith

    IPC分类号： B60J7/00

    CPC分类号： B62D25/2036 ,  B62D21/157

    摘要： A construction for an automotive vehicle having a generally vertically extending pillar positioned adjacent a door opening as well as a laterally extending cross member having one end aligned with the pillar adjacent its bottom. A gusset has one end secured to one end of the cross member and a second end secured to the pillar. A crush box is attached to the pillar and includes at least a portion aligned with the second end of the gusset to provide a controlled pillar deformation resulting in a constant force-deformation loading of the gusset during a side impact.

    摘要翻译： 一种用于机动车辆的结构，其具有邻近门开口定位的大致垂直延伸的柱以及横向延伸的横向构件，其一端与邻近其底部的柱对准。 角撑板的一端固定在横梁的一端，固定在支柱上的第二端。 粉碎箱附接到支柱并且包括至少一部分与角撑板的第二端对准的部分，以提供受控的柱形变形，从而在侧面碰撞期间导致角撑板的恒定的力变形负载。