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公开(公告)号:US20050081364A1
公开(公告)日:2005-04-21
申请号:US10753094
申请日:2004-01-07
申请人: Robert Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
发明人: Robert Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
CPC分类号: B25F3/00 , B25F5/02 , B25F5/026 , B25F5/029 , B27C5/10 , Y10T16/444 , Y10T16/4713 , Y10T29/50 , Y10T409/304088 , Y10T409/306496 , Y10T409/306608 , Y10T409/308176
摘要: An attachment for a hand-held power tool, such as a rotary cutting tool, is disclosed. The attachment is configured for selective coupling to a rotary cutting tool and includes a handle that is substantially perpendicular to a central longitudinal axis of the rotary cutting tool when the attachment is coupled to the rotary cutting tool.
摘要翻译: 公开了一种用于诸如旋转切削工具的手持式电动工具的附件。 附件被配置为选择性地联接到旋转切割工具,并且包括当附件联接到旋转切割工具时基本上垂直于旋转切削工具的中心纵向轴线的手柄。
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公开(公告)号:US20070022595A1
公开(公告)日:2007-02-01
申请号:US11544141
申请日:2006-10-06
申请人: Robert Kopras , Scott Adler , Brian Albrecht
发明人: Robert Kopras , Scott Adler , Brian Albrecht
IPC分类号: B23P23/00
CPC分类号: B25F3/00 , B25F5/026 , B25F5/029 , B27C5/10 , Y10T16/444 , Y10T16/4713 , Y10T29/50 , Y10T409/304088 , Y10T409/306496 , Y10T409/306608 , Y10T409/308176
摘要: An attachment for a rotary cutting tool includes a first member for selectively coupling the attachment to a rotary cutting tool at a first location and a second member for selectively coupling the attachment to the rotary cutting tool at a second location. The attachment also includes a body extending between the first member and the second member and a handle extending from the body at a location between the first member and the second member and oriented substantially perpendicular to the body. The body is arranged between the handle and the rotary cutting tool when the attachment is coupled to the rotary cutting too. The attachment also includes a shaft extending from within the body and a base coupled to shaft and configured for contacting a workpiece when the rotary cutting tool is forming cuts in the workpiece.
摘要翻译: 用于旋转切割工具的附件包括用于在第一位置处将附件选择性地联接到旋转切削工具的第一构件和用于在第二位置处将附件选择性地联接到旋转切削工具的第二构件。 附件还包括在第一构件和第二构件之间延伸的主体和在第一构件和第二构件之间的位置处从主体延伸并且基本上垂直于主体定向的手柄。 当连接件与旋转切割连接时,主体设置在手柄和旋转切削工具之间。 所述附件还包括从所述主体内延伸的轴和联接到轴的基部,并且构造成用于当所述旋转切削工具在所述工件中形成切口时接触工件。
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公开(公告)号:US20050009458A1
公开(公告)日:2005-01-13
申请号:US10791671
申请日:2004-03-02
申请人: Al Uzumcu , Scott Adler , Brian Albrecht , Timothy Baker
发明人: Al Uzumcu , Scott Adler , Brian Albrecht , Timothy Baker
CPC分类号: B23Q5/045 , B23D47/126 , B23D57/0076 , B24B23/028 , B25F3/00
摘要: An angle attachment for a rotary power tool includes a first assembly including a first shaft and a first gear and a second assembly including a second shaft and a second gear. The second gear engages the first gear and the central longitudinal axis of the second shaft is not collinear or parallel to the central longitudinal axis of the first shaft. The angle attachment further includes a member configured for removable coupling to a motor shaft of a rotary power tool and for removable coupling with the first assembly. At least a portion of the member is configured for insertion into a component of the first assembly.
摘要翻译: 用于旋转动力工具的角度附件包括包括第一轴和第一齿轮的第一组件和包括第二轴和第二齿轮的第二组件。 第二齿轮接合第一齿轮,并且第二轴的中心纵向轴线不共线或平行于第一轴的中心纵向轴线。 角度附件还包括构造成用于可拆卸地联接到旋转动力工具的马达轴并且用于与第一组件可移动联接的构件。 构件的至少一部分被构造成用于插入到第一组件的部件中。
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公开(公告)号:US07077736B2
公开(公告)日:2006-07-18
申请号:US10791671
申请日:2004-03-02
申请人: Al Uzumcu , Scott Adler , Brian Albrecht , Timothy D. Baker
发明人: Al Uzumcu , Scott Adler , Brian Albrecht , Timothy D. Baker
IPC分类号: B24B23/00
CPC分类号: B23Q5/045 , B23D47/126 , B23D57/0076 , B24B23/028 , B25F3/00
摘要: An angle attachment for a rotary power tool includes a first assembly including a first shaft and a first gear and a second assembly including a second shaft and a second gear. The second gear engages the first gear and the central longitudinal axis of the second shaft is not collinear or parallel to the central longitudinal axis of the first shaft. The angle attachment further includes a member configured for removable coupling to a motor shaft of a rotary power tool and for removable coupling with the first assembly. At least a portion of the member is configured for insertion into a component of the first assembly.
摘要翻译: 用于旋转动力工具的角度附件包括包括第一轴和第一齿轮的第一组件和包括第二轴和第二齿轮的第二组件。 第二齿轮接合第一齿轮,并且第二轴的中心纵向轴线不共线或平行于第一轴的中心纵向轴线。 角度附件还包括构造成用于可拆卸地联接到旋转动力工具的马达轴并且用于与第一组件可移动联接的构件。 构件的至少一部分被构造成用于插入到第一组件的部件中。
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公开(公告)号:US07131180B2
公开(公告)日:2006-11-07
申请号:US10753094
申请日:2004-01-07
申请人: Robert K. Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
发明人: Robert K. Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
CPC分类号: B25F3/00 , B25F5/02 , B25F5/026 , B25F5/029 , B27C5/10 , Y10T16/444 , Y10T16/4713 , Y10T29/50 , Y10T409/304088 , Y10T409/306496 , Y10T409/306608 , Y10T409/308176
摘要: An attachment for a hand-held power tool, such as a rotary cutting tool, is disclosed. The attachment is configured for selective coupling to a rotary cutting tool and includes a handle that is substantially perpendicular to a central longitudinal axis of the rotary cutting tool when the attachment is coupled to the rotary cutting tool.
摘要翻译: 公开了一种用于诸如旋转切削工具的手持式电动工具的附件。 附件被配置为选择性地联接到旋转切割工具,并且包括当附件联接到旋转切割工具时基本上垂直于旋转切削工具的中心纵向轴线的手柄。
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公开(公告)号:US07854054B2
公开(公告)日:2010-12-21
申请号:US11544141
申请日:2006-10-06
申请人: Robert K. Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
发明人: Robert K. Kopras , Al Uzumcu , Scott Adler , Brian Albrecht
CPC分类号: B25F3/00 , B25F5/026 , B25F5/029 , B27C5/10 , Y10T16/444 , Y10T16/4713 , Y10T29/50 , Y10T409/304088 , Y10T409/306496 , Y10T409/306608 , Y10T409/308176
摘要: An attachment for a rotary cutting tool includes a first member for selectively coupling the attachment to a rotary cutting tool at a first location and a second member for selectively coupling the attachment to the rotary cutting tool at a second location. The attachment also includes a body extending between the first member and the second member and a handle extending from the body at a location between the first member and the second member and oriented substantially perpendicular to the body. The body is arranged between the handle and the rotary cutting tool when the attachment is coupled to the rotary cutting too. The attachment also includes a shaft extending from within the body and a base coupled to shaft and configured for contacting a workpiece when the rotary cutting tool is forming cuts in the workpiece.
摘要翻译: 用于旋转切割工具的附件包括用于在第一位置处将附件选择性地联接到旋转切削工具的第一构件和用于在第二位置处将附件选择性地联接到旋转切削工具的第二构件。 附件还包括在第一构件和第二构件之间延伸的主体和在第一构件和第二构件之间的位置处从主体延伸并且基本上垂直于主体定向的手柄。 当连接件与旋转切割连接时,主体设置在手柄和旋转切削工具之间。 所述附件还包括从所述主体内延伸的轴和联接到轴的基部,并且构造成用于当所述旋转切削工具在所述工件中形成切口时接触工件。
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公开(公告)号:US20070173521A1
公开(公告)日:2007-07-26
申请号:US11599901
申请日:2006-11-14
申请人: Qiufen Xue , Brian Albrecht , Denise Andersen , Michael Bartberger , James Brown , Ryan Brown , Stuart Chaffee , Yuan Cheng , Michael Croghan , Russell Graceffa , Scott Harried , Stephen Hitchcock , Randall Hungate , Ted Judd , Matthew Kaller , Charles Kreiman , Daniel La , Patricia Lopez , Craig Masse , Holger Monenschein , Thomas Nguyen , Thomas Nixey , Vinod Patel , Lewis Pennington , Matthew Weiss , Bryant Yang , Wenge Zhong
发明人: Qiufen Xue , Brian Albrecht , Denise Andersen , Michael Bartberger , James Brown , Ryan Brown , Stuart Chaffee , Yuan Cheng , Michael Croghan , Russell Graceffa , Scott Harried , Stephen Hitchcock , Randall Hungate , Ted Judd , Matthew Kaller , Charles Kreiman , Daniel La , Patricia Lopez , Craig Masse , Holger Monenschein , Thomas Nguyen , Thomas Nixey , Vinod Patel , Lewis Pennington , Matthew Weiss , Bryant Yang , Wenge Zhong
IPC分类号: A61K31/513 , A61K31/506
CPC分类号: C07D405/12 , C07D413/12
摘要: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein R1, W, B, R3, R4, R5, i and j are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, methods of use for these compounds, including treatment of AD and related diseases, by administering the compound(s) of Formula I, or compositions including them, to a subject. The invention also comprises further embodiments of Formulas II and III, intermediates and processes useful for the preparation of compounds of the invention.
摘要翻译: 本发明包括可用于调节β-分泌酶酶活性和用于治疗β-分泌酶介导的疾病(包括阿尔茨海默病(AD))和相关病症的新一类化合物。 在一个实施方案中,化合物具有通式I,其中R 1,W,B,R 3,R 4,R 4, 5,i和j在本文中定义。 本发明还包括药物组合物,其包括一种或多种式I化合物,这些化合物的使用方法,包括治疗AD和相关疾病,通过给受试者施用式I化合物或包含它们的组合物。 本发明还包括式II和III的其它实施方案,可用于制备本发明化合物的中间体和方法。
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公开(公告)号:US20060009453A1
公开(公告)日:2006-01-12
申请号:US11126000
申请日:2005-05-09
申请人: Stephanie Geuns-Meyer , Brian Hodous , Stuart Chaffee , Paul Tempest , Philip Olivieri , Rebecca Johnson , Brian Albrecht , Vinod Patel , Victor Cee , Joseph Kim , Steven Bellon , Xiaotian Zhu , Yuan Cheng , Ning Xi , Karina Romero , Hanh Nguyen , Holly Deak
发明人: Stephanie Geuns-Meyer , Brian Hodous , Stuart Chaffee , Paul Tempest , Philip Olivieri , Rebecca Johnson , Brian Albrecht , Vinod Patel , Victor Cee , Joseph Kim , Steven Bellon , Xiaotian Zhu , Yuan Cheng , Ning Xi , Karina Romero , Hanh Nguyen , Holly Deak
IPC分类号: A61K31/53 , A61K31/506 , C07D43/14
CPC分类号: C07D213/73 , C07D239/42 , C07D401/04 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/14 , C07D471/04
摘要: The present invention relates to chemical compounds having a general formula I wherein A, B, D, E, G, H1-5 and R1-4 are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of these kinases. For example, the compounds are capable of modulating kinase enzymes thereby influencing the process of angiogenesis and treating angiogenesis-related diseases and other poliferative disorders, including cancer and inflammation. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of protein kinases.
摘要翻译: 本发明涉及具有通式I的化合物,其中A,B,D,E,G,H 1-5和R 1-4如本文所定义, 和合成中间体,其能够调节各种蛋白激酶受体酶,从而影响与这些激酶的活性相关的各种疾病状态和状况。 例如,这些化合物能够调节激酶,从而影响血管生成过程并治疗血管生成相关疾病和其它包括癌症和炎症的复发性疾病。 本发明还包括药物组合物,包括该化合物,以及治疗与蛋白激酶活性有关的疾病状态的方法。
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公开(公告)号:US20130009963A1
公开(公告)日:2013-01-10
申请号:US13178457
申请日:2011-07-07
申请人: Brian Albrecht
发明人: Brian Albrecht
IPC分类号: G06T13/00
CPC分类号: G06T13/80 , G06T11/206
摘要: An animated graphic transition is displayed to represent a data difference between data sets. A plurality of data sets is provided, and a user is presented with a plurality of options that includes selection of one or more data sets. A user selection from the plurality of options is detected. Displayed are a first graphic element that represents data in one data set and a second graphic element that represents data in another data set. An animated graphic transition is displayed in conjunction with the first and second graphic elements to represent a data difference between the selected data sets.
摘要翻译: 显示动画图形转换表示数据集之间的数据差异。 提供多个数据集,并向用户呈现包括选择一个或多个数据集的多个选项。 检测来自多个选项的用户选择。 显示的是表示一个数据集中的数据的第一图形元素和表示另一数据集中的数据的第二图形元素。 结合第一和第二图形元素显示动画图形转换,以表示所选数据集之间的数据差异。
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公开(公告)号:US20120267387A1
公开(公告)日:2012-10-25
申请号:US13497459
申请日:2010-09-22
申请人: Paul Omdoll , Brian Albrecht , Scott Collins
发明人: Paul Omdoll , Brian Albrecht , Scott Collins
CPC分类号: A47K10/32 , A47K2010/3233
摘要: A transformable towel dispenser is presented that can be quickly transformed from a low profile shipping form into full, ready to dispense form in a substantially tool free manner. The transformability of the dispenser allows the dispenser to be shipped and stored in much smaller space than that for ready to dispense units. Alternatively, more dispensers can be shipped in the same volume container.
摘要翻译: 提供了一种可变形的毛巾分配器,可以从基本上无工具的方式快速地从低调的运输形式转变为完全准备分配的形式。 分配器的可变性允许分配器运输和存储在比准备分配单元小得多的空间中。 或者,更多的分配器可以在相同的容积容器中运输。
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