公开(公告)号：US06258109B1

公开(公告)日：2001-07-10

申请号：US09656339

申请日：2000-09-06

申请人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

发明人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

IPC分类号： A61B1722

CPC分类号： A61B17/320758 ,  A61B2017/320004

摘要： A guide wire for use in atherectomy procedures has a bearing with a static member fixedly secured to the guide wire and a dynamic member rotatably engaged to the static member. The dynamic member can rotate with an atherectomy burr if the burr engages the bearing.

摘要翻译： 用于粥样斑块切除术的导丝具有固定在引导线上的静止部件和与该静止部件可旋转接合的动力部件的轴承。 如果毛刺接合轴承，动态构件可以用粥状斑切除术毛发旋转。

公开(公告)号：US06270509B1

公开(公告)日：2001-08-07

申请号：US09655907

申请日：2000-09-06

申请人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

发明人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

IPC分类号： A61B1722

CPC分类号： A61B17/320758 ,  A61B2017/320004

摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially thorough the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. The leading surface of the burr may include one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸穿过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 毛刺的前导表面可以包括一个或多个抽吸端口，通过该吸口可以从患者的血管中除去从闭塞中消除的碎屑。

公开(公告)号：US06183487B2

公开(公告)日：2001-02-06

申请号：US09178450

申请日：1998-10-23

申请人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

发明人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

IPC分类号： A61B1722

CPC分类号： A61B17/320758 ,  A61B2017/320004

摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially through the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. In an alternative embodiment of the invention, the leading surface of the burr includes one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸通过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 在本发明的替代实施例中，毛刺的前表面包括一个或多个抽吸端口，通过该抽吸端口可以从患者的血管移除从闭塞中消除的碎屑。

公开(公告)号：US06328750B1

公开(公告)日：2001-12-11

申请号：US09655905

申请日：2000-09-06

申请人： Robert Lawrence Berry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

发明人： Robert Lawrence Berry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

IPC分类号： A61B1732

CPC分类号： A61B17/320758 ,  A61B2017/320004

摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially through the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. In an alternative embodiment, the leading surface of the burr includes one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。毛刺的前表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸通过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 在替代实施例中，毛刺的前表面包括一个或多个抽吸端口，通过该抽吸端口可以从患者的血管移除从闭塞中消除的碎屑。

公开(公告)号：US06416526B1

公开(公告)日：2002-07-09

申请号：US09589861

申请日：2000-06-08

申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

IPC分类号： A61B1732

CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

公开(公告)号：US06096054A

公开(公告)日：2000-08-01

申请号：US178449

申请日：1998-10-23

申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。