Blood flow reestablishment determination
    6.
    发明授权
    Blood flow reestablishment determination 有权
    血流重建确定

    公开(公告)号:US06979293B2

    公开(公告)日:2005-12-27

    申请号:US10320847

    申请日:2002-12-16

    摘要: A method for monitoring a clot dissolution treatment in a patient's vasculature comprises positioning a catheter at a treatment site in the patient's vasculature. The method further comprises performing a clot dissolution treatment at the treatment site. The clot dissolution treatment comprises delivering ultrasonic energy and a therapeutic compound from the catheter to the treatment site such that a clot located at the treatment site at least partially dissolves. The method further comprises delivering a thermal measurement signal from a first portion of the catheter to the treatment site during the clot dissolution treatment. The method further comprises receiving the thermal measurement signal at a second portion of the catheter. The method further comprises comparing the delivered thermal measurement signal with the received thermal measurement signal to evaluate a blood flow rate at the treatment site.

    摘要翻译: 用于监测患者脉管系统中的凝块溶解治疗的方法包括将导管定位在患者脉管系统的治疗部位。 该方法还包括在治疗部位进行凝块溶解处理。 凝块溶解处理包括将超声能量和治疗化合物从导管输送到治疗部位,使得位于治疗部位的血块至少部分溶解。 该方法还包括在凝块溶解治疗期间将热测量信号从导管的第一部分输送到治疗部位。 该方法还包括在导管的第二部分处接收热测量信号。 该方法还包括比较传送的热测量信号与接收的热测量信号,以评估处理部位的血液流速。

    Cancave atherectomy burr with smooth rims
    7.
    发明授权
    Cancave atherectomy burr with smooth rims 失效
    具有平滑轮缘的粥样斑块切除术

    公开(公告)号:US06270509B1

    公开(公告)日:2001-08-07

    申请号:US09655907

    申请日:2000-09-06

    IPC分类号: A61B1722

    摘要: An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially thorough the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. The leading surface of the burr may include one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

    摘要翻译: 消融毛刺具有主体,该主体设置有内圆周边缘和外圆周边缘,所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面,其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂,例如金刚石砂粒,提供在前表面上。 毛刺被驱动轴选择性地旋转,导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要,线材同轴地延伸穿过本体,使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端,并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成,以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端,可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件,并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 毛刺的前导表面可以包括一个或多个抽吸端口,通过该吸口可以从患者的血管中除去从闭塞中消除的碎屑。

    Ablation device for reducing damage to vessels and/or in-vivo stents
    8.
    发明授权
    Ablation device for reducing damage to vessels and/or in-vivo stents 失效
    用于减少对血管和/或体内支架的损伤的消融装置

    公开(公告)号:US06183487B2

    公开(公告)日:2001-02-06

    申请号:US09178450

    申请日:1998-10-23

    IPC分类号: A61B1722

    摘要: An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially through the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. In an alternative embodiment of the invention, the leading surface of the burr includes one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

    摘要翻译: 消融毛刺具有主体,该主体设置有内圆周边缘和外圆周边缘,所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面,其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂,例如金刚石砂粒,提供在前表面上。 毛刺被驱动轴选择性地旋转,导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要,线材同轴地延伸通过本体,使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端,并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成,以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端,可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件,并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 在本发明的替代实施例中,毛刺的前表面包括一个或多个抽吸端口,通过该抽吸端口可以从患者的血管移除从闭塞中消除的碎屑。