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    Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel
    1.
    发明授权
    Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel 失效
    可扩展的粥样斑块切除术和从患者血管中消除闭塞的方法

    公开(公告)号：US06096054A

    公开(公告)日：2000-08-01

    申请号：US178449

    申请日：1998-10-23

    申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

    Expandable atherectomy burr
    2.
    发明授权
    Expandable atherectomy burr 失效
    扩张性粥样斑块切除术

    公开(公告)号：US06416526B1

    公开(公告)日：2002-07-09

    申请号：US09589861

    申请日：2000-06-08

    申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    IPC分类号： A61B1732

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

    Trifilar atherectomy driveshaft
    4.
    发明授权
    Trifilar atherectomy driveshaft 有权
    三头粥样斑块驱动轴

    公开(公告)号：US06328750B1

    公开(公告)日：2001-12-11

    申请号：US09655905

    申请日：2000-09-06

    申请人： Robert Lawrence Berry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    发明人： Robert Lawrence Berry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    IPC分类号： A61B1732

    CPC分类号： A61B17/320758 ,  A61B2017/320004

    摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially through the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. In an alternative embodiment, the leading surface of the burr includes one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

    摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。毛刺的前表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸通过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 在替代实施例中，毛刺的前表面包括一个或多个抽吸端口，通过该抽吸端口可以从患者的血管移除从闭塞中消除的碎屑。

    Cancave atherectomy burr with smooth rims
    5.
    发明授权
    Cancave atherectomy burr with smooth rims 失效
    具有平滑轮缘的粥样斑块切除术

    公开(公告)号：US06270509B1

    公开(公告)日：2001-08-07

    申请号：US09655907

    申请日：2000-09-06

    申请人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    发明人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    IPC分类号： A61B1722

    CPC分类号： A61B17/320758 ,  A61B2017/320004

    摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially thorough the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. The leading surface of the burr may include one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

    摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸穿过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 毛刺的前导表面可以包括一个或多个抽吸端口，通过该吸口可以从患者的血管中除去从闭塞中消除的碎屑。

    Ablation device for reducing damage to vessels and/or in-vivo stents
    6.
    发明授权
    Ablation device for reducing damage to vessels and/or in-vivo stents 失效
    用于减少对血管和/或体内支架的损伤的消融装置

    公开(公告)号：US06183487B2

    公开(公告)日：2001-02-06

    申请号：US09178450

    申请日：1998-10-23

    申请人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    发明人： Robert Lawrence Barry ,  Matt Hefner ,  Tom Hiblar ,  Joseph Pearce ,  Natalya Peskin ,  Edward Wulfman

    IPC分类号： A61B1722

    CPC分类号： A61B17/320758 ,  A61B2017/320004

    摘要： An ablation burr has a body provided with an inner circumferential rim and an outer circumferential rim that are concentric and spaced longitudinally by a selected distance along the length of the burr. The outer circumferential rim has a generally smooth convex outer surface that reduces damage to a vessel wall or stent. A leading surface of the burr extends between the inner and outer circumferential rims in a substantially uniform, concave manner. An abrasive, for example, diamond grit, is provided on the leading surface. The burr is selectively rotated by a drive shaft, causing the abrasive leading surface of the burr to ablate unwanted deposits. If desired, a wire extends co-axially through the body such that a distal end of the wire extends out of the distal end of the burr. An abrasive tip may be coupled to the distal end of the wire, and is selectively rotated, to ablate unwanted deposits. The burr may be made of a compressible elastomeric material, to facilitate positioning the burr through restrictive openings, such as the coronary ostia. To prevent the burr from becoming welded to a spring tip at the end of the guide wire, a bearing may be provided at a distal region of the guide wire. The bearing has a dynamic member that acts as a bumper and rotates when the ablation device is advanced to the distal region of the guide wire and contacts the dynamic member. In an alternative embodiment of the invention, the leading surface of the burr includes one or more aspiration ports through which debris that is ablated from the occlusion may be removed from a patient's vessel.

    摘要翻译： 消融毛刺具有主体，该主体设置有内圆周边缘和外圆周边缘，所述内圆周边缘和外圆周边缘同心且沿着毛刺长度方向间隔一段选定距离。 外圆周边缘具有大致平滑的凸形外表面，其减小对血管壁或支架的损伤。 毛刺的前导表面以大致均匀的凹陷方式在内圆周边缘和外圆周边缘之间延伸。 研磨剂，例如金刚石砂粒，提供在前表面上。 毛刺被驱动轴选择性地旋转，导致毛刺的研磨引导表面烧蚀不需要的沉积物。 如果需要，线材同轴地延伸通过本体，使得线材的远端延伸出毛刺的远端。 研磨尖端可以联接到线的远端，并且被选择性地旋转以消除不想要的沉积物。 毛刺可以由可压缩的弹性体材料制成，以便于通过诸如冠状动脉口的限制性开口将毛刺定位。 为了防止毛刺在引导线的端部焊接到弹簧尖端，可以在导丝的远侧区域处设置轴承。 轴承具有作为保险杠的动态构件，并且当消融装置前进到导丝的远侧区域并接触动态构件时旋转。 在本发明的替代实施例中，毛刺的前表面包括一个或多个抽吸端口，通过该抽吸端口可以从患者的血管移除从闭塞中消除的碎屑。

    Atherectomy burr including a bias wire
    10.
    发明授权
    Atherectomy burr including a bias wire 有权
    动脉粥样硬化斑块包括偏心线

    公开(公告)号：US06299623B1

    公开(公告)日：2001-10-09

    申请号：US09589993

    申请日：2000-06-08

    申请人： Edward Wulfman

    发明人： Edward Wulfman

    IPC分类号： A61B1722

    CPC分类号： A61B17/320758 ,  A61B2017/22039 ,  A61B2017/320004

    摘要： An ablation device (10) includes a drive shaft (12) and an ablation burr (14) secured to the distal end of the drive shaft thereto. A guide wire (18) extends through the drive shaft and the ablation burr. To direct the ablation burr laterally within a patient's vessel, the atherectomy device includes one or more bias wires (30) that extend generally parallel to and spaced from the longitudinal axis of the drive shaft such that engagement of the bias wires against an obstruction in a patient's vessel will force the ablation burr to move laterally within a patient's blood vessel. To rotate the bias wires in a patient's blood vessel, the bias wire may be coupled to a catheter surrounding the drive shaft. Alternatively, the catheter is designed to engage the bias wires when the drive shaft is retracted into the catheter. The bias wires will then rotate as the catheter is rotated.

    摘要翻译： 消融装置（10）包括固定到驱动轴的远端的驱动轴（12）和消融毛刺（14）。 引导线（18）延伸穿过驱动轴和消融毛刺。 为了将消融毛刺横向地引导到患者的血管内，动脉粥样斑块切除装置包括一个或多个偏置线（30），该偏置线大致平行于驱动轴的纵向轴线延伸并且与驱动轴的纵向轴线间隔开，使得偏置线与阻塞 患者的血管将迫使消融毛刺在患者的血管内横向移动。为了使患者血管中的偏置线旋转，偏置线可以联接到围绕驱动轴的导管。 或者，当驱动轴缩回到导管中时，导管被设计成接合偏置线。 然后当导管旋转时，偏置线将旋转。