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    Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel
    1.
    发明授权
    Expandable atherectomy burr and method of ablating an occlusion from a patient's blood vessel 失效
    可扩展的粥样斑块切除术和从患者血管中消除闭塞的方法

    公开(公告)号：US06096054A

    公开(公告)日：2000-08-01

    申请号：US178449

    申请日：1998-10-23

    申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

    Expandable atherectomy burr
    2.
    发明授权
    Expandable atherectomy burr 失效
    扩张性粥样斑块切除术

    公开(公告)号：US06416526B1

    公开(公告)日：2002-07-09

    申请号：US09589861

    申请日：2000-06-08

    申请人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    发明人： Mark Wyzgala ,  Donald Baumgarten ,  Lucas S. Gordon ,  Eric B. Hamilton ,  Matt Hefner ,  Tom Hiblar ,  Edward Wulfman

    IPC分类号： A61B1732

    CPC分类号： A61B17/320725 ,  A61B17/320758 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733

    摘要： An atherectomy burr has an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a polymeric balloon that is coated with an abrasive and that expands when the burr is rotated. Alternatively, the burr may include a polymeric tube that is coated with an abrasive and secured to the proximal end of the burr. When the burr is rotated, the polymeric tube expands by centrifugal force. Alternatively, the burr may comprise a metallic strip wound over a mandrel. When the strip is tightly coiled to the mandrel, its outer diameter decreases. The outer diameter of the burr increases as the metallic strip expands. In addition, the burr can be formed as a wire spring wound over a drive tube. The distal end of the spring is coupled to a nose cone that can move within a distal lumen in the drive tube. The maximum expansion of the burr is controlled by the distance that the nose cone can be retracted into the lumen. In addition, the present invention includes a burr having an indexable outer diameter. Various indexing mechanisms are disclosed for selectively increasing or decreasing the distance between a proximal and distal end of the burr. As the length of the burr changes, the outer diameter of a number of cutting blades is changed to allow a physician to create different sized lumens in a patient's vessel.

    摘要翻译： 粥样斑块切除术毛刺的操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括涂覆有磨料的聚合物气球，并且当毛刺旋转时膨胀。 或者，毛刺可以包括涂覆有研磨剂并固定到毛刺的近端的聚合物管。 当毛刺旋转时，聚合物管通过离心力膨胀。 或者，毛刺可以包括缠绕在心轴上的金属条。 当条带紧紧地卷绕到心轴上时，其外径减小。 毛边的外径随着金属条扩张而增加。 此外，毛刺可以形成为卷绕在驱动管上的线弹簧。 弹簧的远端联接到能够在驱动管内远端管腔内移动的鼻锥体。 毛刺的最大膨胀由鼻锥可以缩回到内腔的距离来控制。 此外，本发明包括具有可转位外径的毛刺。 公开了用于选择性地增加或减小毛刺的近端和远端之间的距离的各种分度机构。 随着毛刺的长度改变，许多切割刀片的外径被改变以允许医师在患者的血管中产生不同大小的腔。

    Transluminal thrombectomy apparatus
    3.
    发明授权
    Transluminal thrombectomy apparatus 失效
    腔内血栓切除术

    公开(公告)号：US5695507A

    公开(公告)日：1997-12-09

    申请号：US617259

    申请日：1996-03-18

    申请人： David C. Auth ,  Thomas J. Clement ,  Lucas S. Gordon

    发明人： David C. Auth ,  Thomas J. Clement ,  Lucas S. Gordon

    IPC分类号： A61B17/22 ,  A61B19/00 ,  A61B17/32

    CPC分类号： A61B17/320758 ,  A61B17/22031 ,  A61B17/320783 ,  A61B2017/22084 ,  A61B2017/320733 ,  A61M2025/0183

    摘要： The invention is an apparatus for breaking up a thrombus by introducing a tating core wire into the thrombus whereby the fibrin of the thrombus will be withdrawn from the thrombus into the rotating core wire, thereby breaking up the network of the thrombus which prevents blood flow. The apparatus includes a drive shaft housing which can be used to withdraw fluid from the area of the thrombus or to introduce medicines, such as streptokinase which will further break up the thrombus or other chemicals such as contrast agents for visualizing the vascular anatomy. The apparatus also includes a shaft housing which is provided with an expanded catheter funnel at the distal end and a venturi insert immediately proximal to the distal end. The apparatus further includes a prime mover which, in addition to rotating the drive shaft, allows for axial motion of the drive shaft relative to the drive shaft housing.

    摘要翻译： 本发明是一种通过将旋转的芯线引入血栓来分解血栓的装置，由此血栓的纤维蛋白将从血栓中排出到旋转的芯线中，从而破坏了防止血液流动的血栓网络。 该装置包括驱动轴壳体，该驱动轴壳体可用于从血栓区域抽出流体或引入药物，例如链激酶，其将进一步分解血栓或其它化学物质，例如用于可视化血管解剖结构的造影剂。 该装置还包括轴壳体，其在远端设置有扩张的导管漏斗，并且在靠近远端的位置处设有文氏管插入件。 该装置还包括原动机，除了旋转驱动轴之外，原动机允许驱动轴相对于驱动轴壳体的轴向运动。

    Liquid and gas separation system
    4.
    发明授权
    Liquid and gas separation system 失效
    液气分离系统

    公开(公告)号：US5039486A

    公开(公告)日：1991-08-13

    申请号：US338347

    申请日：1989-04-12

    申请人： Lucas S. Gordon

    发明人： Lucas S. Gordon

    IPC分类号： A61M1/36 ,  B01D19/00 ,  B01D19/02

    CPC分类号： A61M1/3627 ,  B01D19/0031 ,  B01D19/02 ,  Y10S128/03 ,  Y10S261/28

    摘要： A defoaming device for separating foam and bubbles from a liquid, such as blood, is disclosed. The device can be used in conjunction with a medical device, such as a membrane oxygenator, for separating air from blood while minimizing blood contact with the antifoam agent used in the device. The device includes a reservoir and a filtering material that does not contain any antifoaming agent. This filtering material is positioned in a lower portion of the reservoir to separate foam and bubbles from the liquid. An element containing an antifoaming agent is positioned in the reservoir above the maximum surface fluid level therein and receives the foam and bubbles that rise from the filtering material. Contact of the liquid with the antifoaming agent is substantially avoided.

    摘要翻译： 公开了一种用于从诸如血液的液体中分离泡沫和气泡的消泡装置。 该装置可以与诸如膜式氧合器的医疗装置结合使用，用于将血液与血液分离，同时最小化与装置中使用的消泡剂的血液接触。 该装置包括不包含任何消泡剂的储存器和过滤材料。 该过滤材料定位在储存器的下部，以将泡沫和气泡与液体分开。 含有消泡剂的元素位于储存器中高于其中最大表面液面的位置，并接收从过滤材料上升的泡沫和气泡。 基本上避免了液体与消泡剂的接触。

    Apparatus and method for the autotransfusion of blood
    5.
    发明授权
    Apparatus and method for the autotransfusion of blood 失效
    用于血液自体输血的装置和方法

    公开(公告)号：US4935002A

    公开(公告)日：1990-06-19

    申请号：US213241

    申请日：1988-06-29

    申请人： Lucas S. Gordon

    发明人： Lucas S. Gordon

    IPC分类号： A61M1/02 ,  A61M1/34 ,  A61M1/36 ,  B01D29/01 ,  B01D61/14 ,  B01D61/18 ,  B01D63/08 ,  B01D63/16 ,  B01D65/08

    CPC分类号： B01D63/16 ,  A61M1/02 ,  A61M1/262 ,  A61M1/34 ,  A61M1/3692 ,  B01D29/012 ,  B01D61/142 ,  B01D61/18 ,  B01D63/084 ,  B01D65/08 ,  A61M1/3675 ,  A61M1/3693 ,  A61M2205/7563 ,  B01D2321/2058

    摘要： Autotransfusion apparatus and methods are disclosed for collecting, processing and returning blood to a patient during or after surgery. The processing step of the autotransfusion system comprises sequential rough filtering and filtering of the blood. Filtering is achieved within a single filter housing which includes a first ultrafiltration zone where blood fluids and anticoagulant are separated and removed from red blood cells, a washing zone where washing solution is injected into the remaining concentrated red blood cell solution and a second filtration zone where washing solution, residual blood fluids and anticoagulant are separated and removed from the washed and concentrated red blood cell solution. The filtration includes a rotating disc which creates a shear force upon the blood to prevent clotting and red blood cell build up along the face of filter membranes.

    摘要翻译： 公开了用于在手术期间或之后收集，处理和返回患者血液的自体输血装置和方法。 自动输血系统的处理步骤包括对血液进行连续粗略过滤和过滤。 在单个过滤器壳体内实现过滤，所述过滤器壳体包括第一超滤区域，其中血液和抗凝血剂从红细胞中分离和除去，洗涤区域将洗涤溶液注入剩余的浓缩红细胞溶液中，第二过滤区域 洗涤溶液，残余血液和抗凝血剂从洗涤和浓缩的红细胞溶液中分离并除去。 过滤包括旋转盘，其在血液上产生剪切力以防止凝结，并且沿着过滤膜的表面积聚红细胞。

    Percutaneous Mitral Valve Annuloplasty Delivery System
    8.
    发明申请
    Percutaneous Mitral Valve Annuloplasty Delivery System 审中-公开
    经皮二尖瓣瓣膜成形术输送系统

    公开(公告)号：US20110066234A1

    公开(公告)日：2011-03-17

    申请号：US12952057

    申请日：2010-11-22

    申请人： Lucas S. Gordon ,  Mark L. Mathis ,  Gregory Nieminen ,  Leonard Kowalsky ,  Ryan Braxtan ,  Brian J. Doll

    发明人： Lucas S. Gordon ,  Mark L. Mathis ,  Gregory Nieminen ,  Leonard Kowalsky ,  Ryan Braxtan ,  Brian J. Doll

    IPC分类号： A61F2/24

    CPC分类号： A61B17/3468 ,  A61F2/2451 ,  A61F2/95 ,  A61F2002/9511 ,  A61F2002/9517

    摘要： The invention is a tissue shaping system, including a tissue shaping device with an expandable anchor and a lock; a delivery catheter; a delivery mechanism adapted to deliver the tissue shaping device from outside a patient to a target site within a lumen within the patient via the delivery catheter; and an actuator adapted to deliver an actuation force to the lock to lock the anchor in an expanded configuration. The invention is also a system adapted to percutaneously deliver and deploy a tissue shaping device at a target site within a lumen of a patient. The system includes: a handle; a delivery mechanism supported by the handle and adapted to deliver the tissue shaping device from outside the patient to the treatment site via a delivery catheter; and an actuator supported by the handle and adapted to deliver an actuation force to lock an anchor of the tissue shaping device in an expanded configuration.

    摘要翻译： 本发明是一种组织成形系统，包括具有可扩张锚和锁的组织成形装置; 输送导管; 输送机构，其适于经由输送导管将患者外部的组织成形装置输送到患者体内的内腔内的目标部位; 以及致动器，其适于将致动力传递到所述锁以将所述锚固件锁定在扩展构型中。 本发明也是适于在患者的内腔内的目标部位经皮输送和部署组织整形装置的系统。 该系统包括：手柄; 由手柄支撑并适于经由输送导管将组织成形装置从患者外部递送到治疗部位的递送机构; 以及致动器，其由所述手柄支撑并且适于递送致动力以将所述组织整形装置的锚固件以扩展构型锁定。