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    Internal restraint for delivery of self-expanding stents
    5.
    发明授权
    Internal restraint for delivery of self-expanding stents 有权
    自我扩张支架的内部限制

    公开(公告)号：US08303616B2

    公开(公告)日：2012-11-06

    申请号：US11028808

    申请日：2005-01-03

    申请人： Robert M. Abrams ,  Elaine Lee

    发明人： Robert M. Abrams ,  Elaine Lee

    IPC分类号： A61M29/00

    CPC分类号： G06Q10/00 ,  A61F2/95 ,  A61F2002/9511 ,  G06F19/00 ,  G06Q50/22 ,  G06Q50/24

    摘要： A medical device delivery system comprises a catheter having a catheter shaft with a proximal region and a distal region. The catheter shaft has a pull wire lumen therein. An expandable medical device is disposed about medical device receiving region of the catheter shaft. The expandable medical device has a reduced configuration and an expanded configuration. The system further comprises a retractable retaining wire, at least a portion of which is coiled about the expandable medical device and retains the expandable medical device in the reduced configuration. One end of the retractable retaining wire terminates in a pull-wire. The pull-wire extends into the pull-wire lumen to the proximal region of the catheter shaft.

    摘要翻译： 医疗装置输送系统包括具有导管轴的导管，其具有近端区域和远端区域。 导管轴在其中具有拉丝腔。 可扩张医疗装置设置在导管轴的医疗装置接收区域周围。 可扩展医疗设备具有减小的配置和扩展配置。 该系统进一步包括可缩回保持线，其至少一部分围绕可扩张医疗装置卷绕并将可扩张医疗装置保持在减小的构型。 可伸缩保持线的一端终止于拉线。 拉线延伸到拉线管腔到导管轴的近端区域。

    MODULAR STEERABLE SHEATH CATHETERS
    6.
    发明申请
    MODULAR STEERABLE SHEATH CATHETERS 有权
    模块式可转向导管

    公开(公告)号：US20090124978A1

    公开(公告)日：2009-05-14

    申请号：US12353112

    申请日：2009-01-13

    申请人： Robert M. Abrams ,  Michael P. Wallace

    发明人： Robert M. Abrams ,  Michael P. Wallace

    IPC分类号： A61B17/34

    CPC分类号： A61M25/0662 ,  A61M25/10 ,  A61M2025/0006 ,  A61M2025/0293 ,  A61M2025/0681 ,  A61M2025/09125 ,  A61M2025/1063

    摘要： An apparatus for accessing a site within a body includes a cannula and an elongate member. The cannula has a proximal end, a distal end, and a lumen extending therebetween. The elongate member has a distal end configured for insertion into the lumen, wherein the distal end of the elongate member is attachable to and releasable from the distal end of the cannula. A method for accessing a site within a body includes inserting a distal end of an elongate member into a lumen of a cannula, detachably attaching the distal end of the elongate member to the cannula, and steering a distal end of the cannula to a desired site using the elongate member.

    摘要翻译： 用于进入体内部位的装置包括套管和细长构件。 套管具有近端，远端和在其间延伸的内腔。 细长构件具有构造成用于插入内腔的远端，其中细长构件的远端可附接到插管的远端并且可从插管的远端释放。 用于访问体内部位的方法包括将细长构件的远端插入套管的内腔，将细长构件的远端可拆卸地连接到套管上，并将套管的远端转向所需位置 使用细长构件。

    Superelastic guiding member
    7.
    发明授权
    Superelastic guiding member 失效
    超弹性引导构件

    公开(公告)号：US06682608B2

    公开(公告)日：2004-01-27

    申请号：US10117155

    申请日：2002-04-05

    申请人： Robert M. Abrams ,  Sepehr Fariabi

    发明人： Robert M. Abrams ,  Sepehr Fariabi

    IPC分类号： C22C1903

    CPC分类号： A61L31/14 ,  A61L31/022 ,  A61L2400/16 ,  A61M25/09 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

    摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

    Superelastic guiding member
    8.
    发明授权
    Superelastic guiding member 失效
    超弹性引导构件

    公开(公告)号：US06461453B1

    公开(公告)日：2002-10-08

    申请号：US09589646

    申请日：2000-06-07

    申请人： Robert M. Abrams ,  Sepehr Fariabi

    发明人： Robert M. Abrams ,  Sepehr Fariabi

    IPC分类号： C22C1903

    CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

    摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

    Superelastic guiding member
    9.
    发明授权
    Superelastic guiding member 失效
    超弹性引导构件

    公开(公告)号：US06165292A

    公开(公告)日：2000-12-26

    申请号：US484218

    申请日：1995-06-07

    申请人： Robert M. Abrams ,  Sepehr Fariabi

    发明人： Robert M. Abrams ,  Sepehr Fariabi

    IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  C22F1/10 ,  C22K1/00

    CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

    摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450.degree. and about 600.degree. C. and preferably about 475.degree. to about 550.degree. C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

    摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

    Superelastic guiding member
    10.
    发明授权
    Superelastic guiding member 失效
    超弹性引导构件

    公开(公告)号：US5637089A

    公开(公告)日：1997-06-10

    申请号：US598639

    申请日：1996-02-12

    申请人： Robert M. Abrams ,  Sepehr Fariabi

    发明人： Robert M. Abrams ,  Sepehr Fariabi

    IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  A61M37/00

    CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266

    摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450.degree. and about 600.degree. C. and preferably about 475.degree. to about 550.degree. C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

    摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。