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公开(公告)号:US07932743B1
公开(公告)日:2011-04-26
申请号:US12699703
申请日:2010-02-03
申请人: Rodney Stewart , Michael Huebner , Juan J. Noguera Serra , Robert P. Esser , Jurgen Becker , Oliver Sander , Matthias Traub , Joachim H. Meyer
发明人: Rodney Stewart , Michael Huebner , Juan J. Noguera Serra , Robert P. Esser , Jurgen Becker , Oliver Sander , Matthias Traub , Joachim H. Meyer
IPC分类号: H03K19/173 , H01L25/00
CPC分类号: H03K19/17776 , H03K19/17756 , H03K19/17784
摘要: A programmable integrated circuit performs an initial partial configuration of the programmable integrated circuit in response to receiving an activation signal. In this way, the programmable integrated circuit enables an initial functionality of the programmable integrated circuit. The programmable integrated circuit then performs a subsequent partial configuration of the programmable integrated circuit for enabling additional functionality of the programmable integrated circuit. In some embodiments, the programmable integrated circuit receives an input signal indicating a stimulus in an environment of the programmable integrated circuit and determines based on the input signal whether to perform the subsequent partial configuration of the programmable integrated circuit or generate a power down signal for powering down the programmable integrated circuit without performing the subsequent partial configuration. In some embodiments, the programmable integrated circuit performs a sequence of partial subsequent configurations for enabling a sequence of additional functionalities of the programmable integrated circuit.
摘要翻译: 可编程集成电路响应于接收到激活信号而执行可编程集成电路的初始部分配置。 以这种方式,可编程集成电路实现了可编程集成电路的初始功能。 然后,可编程集成电路执行可编程集成电路的后续部分配置,以实现可编程集成电路的附加功能。 在一些实施例中,可编程集成电路接收指示可编程集成电路的环境中的刺激的输入信号,并且基于输入信号确定是否执行可编程集成电路的后续部分配置或者产生用于供电的掉电信号 而不执行后续的部分配置。 在一些实施例中,可编程集成电路执行一系列部分后续配置,以实现可编程集成电路的附加功能序列。
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公开(公告)号:US09717791B2
公开(公告)日:2017-08-01
申请号:US13876367
申请日:2011-10-07
IPC分类号: A61K39/395 , C07K16/24 , A61K39/00
CPC分类号: A61K39/3955 , A61K2039/505 , A61K2039/545 , C07K16/244 , C07K2317/34 , C07K2317/76
摘要: The disclosure relates to novel regimens for treating psoriasis, which employ a therapeutically effective amount of an IL-17 antagonist, e.g., an IL-17 binding molecule, e.g., an IL-17 antibody, such as the secukinumab antibody, or an IL-17 receptor binding molecule, e.g., an IL-17 receptor antibody.
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公开(公告)号:US20130202610A1
公开(公告)日:2013-08-08
申请号:US13876367
申请日:2011-10-07
IPC分类号: A61K39/395
CPC分类号: A61K39/3955 , A61K2039/505 , A61K2039/545 , C07K16/244 , C07K2317/34 , C07K2317/76
摘要: The disclosure relates to novel regimens for treating psoriasis, which employ a therapeutically effective amount of an IL-17 antagonist, e.g., an IL-17 binding molecule, e.g., an IL-17 antibody, such as the secukinumab antibody, or an IL-17 receptor binding molecule, e.g., an IL-17 receptor antibody.
摘要翻译: 本公开涉及用于治疗牛皮癣的新方案,其使用治疗有效量的IL-17拮抗剂,例如IL-17结合分子,例如IL-17抗体,例如secukinumab抗体或IL- 17受体结合分子,例如IL-17受体抗体。
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公开(公告)号:US10434172B2
公开(公告)日:2019-10-08
申请号:US14911387
申请日:2014-08-13
IPC分类号: A61K39/395 , C07K16/24 , A61K45/06 , A61K39/00
摘要: The disclosure is directed to methods, treatment regimens, uses, kits and therapies for treating Generalized Pustular Psoriasis (GPP). These methods, treatment regimens, uses, kits and therapies utilize, inter alia, administration of an IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab. Additionally disclosed are improved methods for treating plaque-type psoriasis that utilize up-titration and down-titration of the IL-17 antagonist, e.g., an IL-17 antibody, such as secukinumab, as well as modification of dose frequency. Further disclosed are methods of treating palmoplantar pustular psoriasis using the disclosed IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab.
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