摘要:
There is provided a method in a first communications device operable to communicate with a second device using a network supporting first and second different communication methods. The method comprises: allowing the first device to communicate with the second device using the first communication method; registering the first device on a service platform of the network; requesting from the service platform a second device status indicator of the ability of the second device to communicate using the second communication method; receiving the second device status indicator from the service platform; and, allowing the first device to communicate with the second device using the second communication method in dependence on the received second device status indicator. The second device status indicator depends on the current network connectivity of the second device. At least one of the first and second devices is a mobile telecommunications device.
摘要:
The present invention provides novel human glucagon-like peptide-1 (GLP-1)-receptor modulators that have biological activity similar or superior to native GLP-1 peptide and thus are useful for the treatment or prevention of diseases or disorders associated with GLP activity. Further, the present invention provides novel, chemically modified peptides that not only stimulate insulin secretion in type II diabetics, but also produce other beneficial insulinotropic responses. These synthetic peptide GLP-1 receptor modulators exhibit increased stability to proteolytic cleavage making them ideal therapeutic candidates for oral or parenteral administration. The peptides of this invention show desirable pharmacokinetic properties and desirable potency in efficacy models of diabetes.
摘要:
A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.
摘要:
A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.
摘要:
Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
摘要:
A system is provided for controlling admission to a special admission zone of a live performance event for a plurality of patrons. The special admission zone is separate and distinct from a general admission area of the event and has a fixed maximum capacity. The duration of the event is divided into a plurality of predefined time periods. The system includes a set of patron-issued wristbands containing electronically writeable and readable RFID chips. The RFID chips of each wristband are electronically encoded with a respective unique serial number that is electronically associated with one of the plurality of predefined time periods. A processor is programmed to verify when each patron in possession of a wristband requests entry to the special admission zone and to initiate transmission of event video or event still images to a social media site or event video to a web channel upon successful verification.
摘要:
The present invention provides novel human glucagon-like peptide-1 (GLP-1)-receptor modulators that have biological activity similar or superior to native GLP-1 peptide and thus are useful for the treatment or prevention of diseases or disorders associated with GLP activity. Further, the present invention provides novel, chemically modified compounds that not only stimulate insulin secretion in type II diabetics, but also produce other beneficial insulinotropic responses. These synthetic peptide GLP-1 receptor modulators exhibit increased stability to proteolytic cleavage making them ideal therapeutic candidates for oral or parenteral administration. The compounds of this invention show desirable pharmacokinetic properties and desirable potency in efficacy models of diabetes.
摘要:
The present invention provides novel pharmaceutical compositions comprising a human glucagon-like peptide-1 (GLP-1)-receptor modulator as an active ingredient in a sustained release formulation.