利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

8 条记录 (耗时 0.039 秒)

    Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions
    2.
    发明申请
    Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions 有权
    人胰高血糖素样肽-1调节剂及其在治疗糖尿病和相关病症中的应用

    公开(公告)号：US20060287242A1

    公开(公告)日：2006-12-21

    申请号：US11170968

    申请日：2005-06-30

    申请人： William Ewing ,  Claudio Mapelli ,  Richard Sulsky ,  Tasir Haque ,  Ving Lee ,  Douglas Riexinger ,  Rogelio Martinez ,  Yeheng Zhu

    发明人： William Ewing ,  Claudio Mapelli ,  Richard Sulsky ,  Tasir Haque ,  Ving Lee ,  Douglas Riexinger ,  Rogelio Martinez ,  Yeheng Zhu

    IPC分类号： A61K38/10 ,  C07K7/08

    CPC分类号： C07K7/06 ,  A61K38/00 ,  C07K14/605

    摘要： The present invention provides novel human glucagon-like peptide-1 (GLP-1)-receptor modulators that have biological activity similar or superior to native GLP-1 peptide and thus are useful for the treatment or prevention of diseases or disorders associated with GLP activity. Further, the present invention provides novel, chemically modified peptides that not only stimulate insulin secretion in type II diabetics, but also produce other beneficial insulinotropic responses. These synthetic peptide GLP-1 receptor modulators exhibit increased stability to proteolytic cleavage making them ideal therapeutic candidates for oral or parenteral administration. The peptides of this invention show desirable pharmacokinetic properties and desirable potency in efficacy models of diabetes.

    摘要翻译： 本发明提供了具有与天然GLP-1肽相似或优于天然GLP-1肽的生物活性的新型人胰高血糖素样肽-1（GLP-1） - 受体调节剂，因此可用于治疗或预防与GLP活性相关的疾病或病症 。 此外，本发明提供新颖的化学修饰的肽，其不仅刺激II型糖尿病患者的胰岛素分泌，而且产生其它有益的促胰岛素反应。 这些合成肽GLP-1受体调节剂表现出增加的蛋白水解切割的稳定性，使其成为口服或肠胃外给药的理想治疗候选物。 本发明的肽在糖尿病的功效模型中显示出所需的药代动力学性质和期望的效力。

    Method and apparatus for zoned admission to performance events
    4.
    发明授权
    Method and apparatus for zoned admission to performance events 有权
    划分入场表演活动的方法及装置

    公开(公告)号：US09153082B2

    公开(公告)日：2015-10-06

    申请号：US13555169

    申请日：2012-07-22

    申请人： Rogelio Martinez

    发明人： Rogelio Martinez

    IPC分类号： G06Q10/02 ,  G07C9/00 ,  G06Q30/06

    CPC分类号： G07C9/00007 ,  G06K7/10366 ,  G06Q10/02 ,  G06Q30/06 ,  G07C9/00015 ,  G07C9/00944

    摘要： A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.

    摘要翻译： 公开了一种方法和装置，其包括被配置为允许观众进入特定准入区域的软件或物理准入证书，以便在预定义的持续时间内进行性能阶段。 在同一表演期间，多个观众可以在多个连续的时间段内使用特别入场区。 在各种实施例中，通过划分与演出阶段相邻的普通准入区来创建特殊准入区。 在其他实施例中，特殊入场区可以被构造为围绕舞台的“时装表情”，以提供高架观看。 在其他实施例中，特殊入场区可以形成在室内或室外附近。 在各种实施例中，入学证可以体现在诸如智能电话的计算设备中，而在其他实施例中，入学证可以是配备RFID的腕带的形式。

    METHOD AND APPARATUS FOR ZONED ADMISSION TO PERFORMANCE EVENTS
    5.
    发明申请
    METHOD AND APPARATUS FOR ZONED ADMISSION TO PERFORMANCE EVENTS 审中-公开
    方法和设备进行性能考试

    公开(公告)号：US20130024219A1

    公开(公告)日：2013-01-24

    申请号：US13555169

    申请日：2012-07-22

    申请人： Rogelio Martinez

    发明人： Rogelio Martinez

    IPC分类号： G06Q10/02

    CPC分类号： G07C9/00007 ,  G06K7/10366 ,  G06Q10/02 ,  G06Q30/06 ,  G07C9/00015 ,  G07C9/00944

    摘要： A method and a device are disclosed including a software or physical admission certificate configured to allow admission of a spectator to a special admission zone with a view to a performance stage for a predefined duration of time. The special admission zone is usable by multiple spectators in multiple successive time periods during the same performance. In various embodiments, the special admission zone is created by partitioning a general admission zone adjacent to the performance stage. In other embodiments, the special admission zone may be constructed as a “catwalk” around the stage to provide elevated viewing. In still other embodiments, the special admission zone may be formed near indoor or outdoor stages. In various embodiments, the admission certificate may be embodied in a computing device such as a smartphone, while in other embodiments the admission certificate may be in the form of a RFID equipped wristband.

    摘要翻译： 公开了一种方法和装置，其包括被配置为允许观众进入特定准入区域的软件或物理准入证书，以便在预定义的持续时间内进行性能阶段。 在同一表演期间，多个观众可以在多个连续的时间段内使用特别入场区。 在各种实施例中，通过划分与演出阶段相邻的普通准入区来创建特殊准入区。 在其他实施例中，特殊入场区可以被构造为围绕舞台的时装表演，以提供升高的观看。 在其他实施例中，特殊入场区可以形成在室内或室外附近。 在各种实施例中，入学证可以体现在诸如智能电话的计算设备中，而在其他实施例中，入学证可以是配备RFID的腕带的形式。

    System for zoned admission to performance events with social media or web channel feed of the events
    7.
    发明授权
    System for zoned admission to performance events with social media or web channel feed of the events 有权
    使用社交媒体或网络频道馈送的活动进行表演活动的系统

    公开(公告)号：US09589396B2

    公开(公告)日：2017-03-07

    申请号：US14875149

    申请日：2015-10-05

    申请人： Rogelio Martinez

    发明人： Rogelio Martinez

    IPC分类号： G06Q10/02 ,  G07C9/00 ,  G06Q30/06 ,  G06K7/10

    CPC分类号： G07C9/00007 ,  G06K7/10366 ,  G06Q10/02 ,  G06Q30/06 ,  G07C9/00015 ,  G07C9/00944

    摘要： A system is provided for controlling admission to a special admission zone of a live performance event for a plurality of patrons. The special admission zone is separate and distinct from a general admission area of the event and has a fixed maximum capacity. The duration of the event is divided into a plurality of predefined time periods. The system includes a set of patron-issued wristbands containing electronically writeable and readable RFID chips. The RFID chips of each wristband are electronically encoded with a respective unique serial number that is electronically associated with one of the plurality of predefined time periods. A processor is programmed to verify when each patron in possession of a wristband requests entry to the special admission zone and to initiate transmission of event video or event still images to a social media site or event video to a web channel upon successful verification.

    摘要翻译： 提供一种用于控制许多顾客进入现场表演事件的特别入场区的系统。 特别入场区与事件的一般入场区分开，具有固定的最大容量。 事件的持续时间被分为多个预定时间段。 该系统包括一组包含电子可写和可读取RFID芯片的顾客发行腕带。 每个腕带的RFID芯片以与多个预定义时间段中的一个电子相关联的相应的唯一序列号进行电子编码。 处理器被编程以验证何时拥有腕带的每个顾客在成功验证时要求进入特别准入区域并且发起事件视频或事件静止图像到社交媒体站点或事件视频到网络频道。

    Method and system for facilitating communication between wireless communication devices
    8.
    发明授权
    Method and system for facilitating communication between wireless communication devices 有权
    用于促进无线通信设备之间的通信的方法和系统

    公开(公告)号：US08868072B2

    公开(公告)日：2014-10-21

    申请号：US13370463

    申请日：2012-02-10

    申请人： Rogelio Martinez ,  Phillip Carter ,  Oscar Gallego Gomez ,  Alfonso Gomez ,  Jonathon Marchant

    发明人： Rogelio Martinez ,  Phillip Carter ,  Oscar Gallego Gomez ,  Alfonso Gomez ,  Jonathon Marchant

    IPC分类号： H04W4/00 ,  H04L29/08 ,  H04M3/42 ,  H04L29/06 ,  H04W76/02

    CPC分类号： H04N7/147 ,  H04L51/043 ,  H04L51/36 ,  H04L65/1006 ,  H04L65/1016 ,  H04L65/1073 ,  H04L67/24 ,  H04M3/42374 ,  H04N2007/145 ,  H04W76/10 ,  H04W76/12

    摘要： There is provided a method in a first communications device operable to communicate with a second device using a network supporting first and second different communication methods. The method comprises: allowing the first device to communicate with the second device using the first communication method; registering the first device on a service platform of the network; requesting from the service platform a second device status indicator of the ability of the second device to communicate using the second communication method; receiving the second device status indicator from the service platform; and, allowing the first device to communicate with the second device using the second communication method in dependence on the received second device status indicator. The second device status indicator depends on the current network connectivity of the second device. At least one of the first and second devices is a mobile telecommunications device.

    摘要翻译： 在第一通信设备中提供了一种可操作以使用支持第一和第二不同通信方法的网络与第二设备进行通信的方法。 该方法包括：允许第一设备使用第一通信方法与第二设备进行通信; 在网络的服务平台上注册第一设备; 从所述服务平台向所述第二设备状态指示符请求所述第二设备使用所述第二通信方法进行通信的能力; 从服务平台接收第二设备状态指示符; 并且根据接收到的第二设备状态指示符，允许第一设备使用第二通信方法与第二设备进行通信。 第二个设备状态指示器取决于第二个设备的当前网络连接。 第一和第二设备中的至少一个是移动电信设备。