公开(公告)号：US20060039856A1

公开(公告)日：2006-02-23

申请号：US11255806

申请日：2005-10-21

申请人： Ronald Cowan ,  Perry Renshaw ,  Blaise Frederick ,  Scott Lukas

发明人： Ronald Cowan ,  Perry Renshaw ,  Blaise Frederick ,  Scott Lukas

IPC分类号： A61K51/00 ,  A61K49/06

CPC分类号： G01R33/4806 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4082 ,  A61K31/445 ,  A61K31/522 ,  A61K41/00 ,  A61K49/06

摘要： This invention involves blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) using external stimuli. Different colors of light can be used as the stimulus to assess differential BOLD response to diagnose neurological disorders (e.g., Parkinson's disease, attention deficit disorder, schizophrenia, and substance abuse). In addition, very low dose administration of a drug that affects intracerebral vasculature can enhance BOLD response, facilitating detection and improving diagnostic capabilities. Using a very low dose of d-amphetamine, BOLD response to blue light is increased.

公开(公告)号：US07053064B2

公开(公告)日：2006-05-30

申请号：US10703695

申请日：2003-11-06

申请人： Scott Lukas

发明人： Scott Lukas

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： A61K31/70 ,  A61K31/197 ,  A61K31/513 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076

摘要： The invention provides methods for treating or suppressing tobacco or nicotine usage or dependence involving administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, creatine-containing compound, adenosine-containing, or adenosine-elevating compound to a mammal.

公开(公告)号：US20060217344A1

公开(公告)日：2006-09-28

申请号：US11440488

申请日：2006-05-25

申请人： Scott Lukas

发明人： Scott Lukas

IPC分类号： A61K31/7076 ,  A61K31/7072 ,  A61K31/205

CPC分类号： A61K31/70 ,  A61K31/197 ,  A61K31/513 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076

摘要： The invention provides methods for treating or suppressing tobacco or nicotine usage or dependence involving administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, creatine-containing compound, adenosine-containing, or adenosine-elevating compound to a mammal.

公开(公告)号：US6103703A

公开(公告)日：2000-08-15

申请号：US300107

申请日：1999-04-27

申请人： Perry F. Renshaw ,  Scott Lukas

发明人： Perry F. Renshaw ,  Scott Lukas

IPC分类号： A61K31/513 ,  A61K31/7068

CPC分类号： A61K31/7068 ,  Y10S514/812

摘要： Disclosed herein is a method for reducing stimulant dependencies in mammals that involves administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, such as CDP-choline.

摘要翻译： 本文公开了一种减少哺乳动物兴奋剂依赖性的方法，其涉及给予治疗有效量的含胞嘧啶或含胞苷的化合物如CDP-胆碱。

公开(公告)号：US07601701B2

公开(公告)日：2009-10-13

申请号：US11440488

申请日：2006-05-25

申请人： Scott Lukas

发明人： Scott Lukas

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： A61K31/70 ,  A61K31/197 ,  A61K31/513 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076

摘要： The invention provides methods for treating or suppressing tobacco or nicotine usage or dependence involving administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, creatine-containing compound, adenosine-containing, or adenosine-elevating compound to a mammal.

摘要翻译： 本发明提供了治疗或抑制烟草或尼古丁的使用或依赖性的方法，其涉及向哺乳动物施用治疗有效量的含胞嘧啶或含胞苷化合物，含肌酸的化合物，含腺苷或腺苷升高化合物 。

公开(公告)号：US06465436B2

公开(公告)日：2002-10-15

申请号：US09871760

申请日：2001-05-31

申请人： Scott Lukas ,  David Lee

发明人： Scott Lukas ,  David Lee

IPC分类号： A61K3170

CPC分类号： A61K31/35 ,  A61K31/352 ,  A61K36/488 ,  A61K45/06 ,  A61K2300/00

摘要： Treatment for alcohol dependence or intoxication that involves administering a pharmaceutical composition containing an extract of the kudzu plant, Pueraria lobata.

摘要翻译： 用于酒精依赖或中毒的治疗，其涉及施用含有葛根植物葛根提取物的药物组合物。

公开(公告)号：US5958896A

公开(公告)日：1999-09-28

申请号：US908997

申请日：1997-08-08

申请人： Perry F. Renshaw ,  Scott Lukas

发明人： Perry F. Renshaw ,  Scott Lukas

IPC分类号： A61K31/70 ,  A61K31/505

CPC分类号： A61K31/7068 ,  Y10S514/812

摘要： Disclosed herein is a method for reducing stimulant dependencies in mammals that involves administration of a therapeutically-effective amount of a cytosine-containing or cytidine-containing compound, such as CDP-choline.