公开(公告)号：US08449487B2

公开(公告)日：2013-05-28

申请号：US12516786

申请日：2006-12-01

申请人： Roy Hovland ,  Anders Wallenborg

发明人： Roy Hovland ,  Anders Wallenborg

IPC分类号： A61M1/16

CPC分类号： A61M1/1658 ,  A61M1/166

摘要： A blood treatment apparatus (1) comprising a degassing unit (15) receiving gas-containing fluid and supplying degassed fluid to a fluid chamber (3) of a blood treatment unit (2). The degassing unit has a gas separator (16), a degassing pump (18) to circulate fluid in a degassing line (12), a flow restrictor (17) for reducing the pressure in the degassing line (12), an absolute pressure sensor (19), and a control unit (20) designed to control the speed of said degassing pump from the absolute pressure signal emitted by the pressure sensor. The apparatus comprises a dialysis machine provided with a device for preparing on-line a dialysis liquid from water and concentrates. The apparatus achieves an accurate and reliable regulation of a desired concentration of gas in the dialysis liquid.

摘要翻译： 一种血液处理装置（1），包括接收含有气体的流体的脱气单元（15），并将脱气流体供给到血液处理单元（2）的流体室（3）。 脱气单元具有气体分离器（16），用于在脱气管线（12）中循环流体的脱气泵（18），用于降低脱气管线（12）中的压力的​​限流器（17），绝对压力传感器 （19），以及控制单元（20），其被设计成根据由压力传感器发射的绝对压力信号来控制所述脱气泵的速度。 该装置包括一个透析机，该透析机设置有用于在线制备来自水和浓缩物的透析液的装置。 该设备实现对透析液体中期望浓度的气体的精确和可靠的调节。

公开(公告)号：US20100106071A1

公开(公告)日：2010-04-29

申请号：US12516786

申请日：2006-12-01

申请人： Anders Wallenborg ,  Roy Hovland

发明人： Anders Wallenborg ,  Roy Hovland

IPC分类号： A61M1/14

CPC分类号： A61M1/1658 ,  A61M1/166

摘要： A blood treatment apparatus (1) comprising a degassing unit (15) receiving gas-containing fluid and supplying degassed fluid to a fluid chamber (3) of a blood treatment unit (2). The degassing unit has a gas separator (16), a degassing pump (18) to circulate fluid in a degassing line (12), a flow restrictor (17) for reducing the pressure in the degassing line (12), an absolute pressure sensor (19), and a control unit (20) designed to control the speed of said degassing pump from the absolute pressure signal emitted by the pressure sensor. The apparatus comprises a dialysis machine provided with a device for preparing on-line a dialysis liquid from water and concentrates. The apparatus achieves an accurate and reliable regulation of a desired concentration of gas in the dialysis liquid.

摘要翻译： 一种血液处理装置（1），包括接收含有气体的流体的脱气单元（15），并将脱气流体供给到血液处理单元（2）的流体室（3）。 脱气单元具有气体分离器（16），用于在脱气管线（12）中循环流体的脱气泵（18），用于降低脱气管线（12）中的压力的​​限流器（17），绝对压力传感器 （19），以及控制单元（20），其被设计成根据由压力传感器发射的绝对压力信号来控制所述脱气泵的速度。 该装置包括一个透析机，该透析机设置有用于在线制备来自水和浓缩物的透析液的装置。 该设备实现对透析液体中期望浓度的气体的精确和可靠的调节。

公开(公告)号：US20110201988A1

公开(公告)日：2011-08-18

申请号：US13124258

申请日：2009-10-12

申请人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

发明人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

IPC分类号： A61M1/34 ,  A61M1/36

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M2205/50

摘要： A blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair of blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Flow measurement device which determines at least one blood flow parameter reflecting an average flow in relation to the blood treatment unit during a well-defined period of operation of the apparatus, for example while completing one operation cycle. The at least one blood flow parameter is determined based on a difference between (i) a first amount of fresh blood treatment fluid received into the blood treatment unit, and (ii) a second amount of used blood treatment fluid emitted from the blood treatment unit during another well-defined period.

摘要翻译： 血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 流量测量装置，例如在完成一个操作周期期间，确定在装置的操作的良好定义的周期期间反映相对于血液处理单元的平均流量的至少一个血流参数。 基于（i）接收到血液处理单元中的第一量的新鲜血液处理液和（ii）从血液处理单元发出的第二量的使用的血液处理液的差异来确定至少一个血流参数 在另一个明确的时期。

公开(公告)号：US20130319920A1

公开(公告)日：2013-12-05

申请号：US13824892

申请日：2011-09-14

申请人： Per Hansson ,  Thomas Hertz ,  Mattias Holmer ,  Lennart Jonsson ,  Anders Nilsson ,  Anders Wallenborg ,  Johan Andersson

发明人： Per Hansson ,  Thomas Hertz ,  Mattias Holmer ,  Lennart Jonsson ,  Anders Nilsson ,  Anders Wallenborg ,  Johan Andersson

IPC分类号： A61M1/36

CPC分类号： A61M1/367 ,  A61M1/14 ,  A61M1/1601 ,  A61M1/3621 ,  A61M2205/3317 ,  A61M2205/3334 ,  A61M2205/50 ,  Y10T29/49002

摘要： A blood treatment apparatus comprising: a blood treatment unit; a blood line configured to extract blood from a blood source, pass the blood through the blood treatment unit and deliver treated blood to a target vessel; and a fluid line configured pass treatment fluid through the blood treatment unit and deliver used treatment fluid to a fluid sink. A flow divider is arranged in the fluid line separates treatment fluid into to a first fluid section and a second fluid section, thereby electrically isolating the fluid sections such that electrical current flowing in the fluid line between the fluid sections is limited. Related manufacturing and verification methods are also described.

摘要翻译： 一种血液处理装置，包括：血液处理单元; 构成为从血液源提取血液的血液线，使血液通过血液处理单元，将处理后的血液输送到目标血管; 并且流体管线配置使处理流体通过血液处理单元并将使用的处理流体输送到流体槽。 流体分配器设置在流体管线中，将处理流体分离成第一流体部分和第二流体部分，由此电流隔离流体部分，使得在流体部分之间的流体管线中流动的电流受到限制。 还描述了相关的制造和验证方法。

公开(公告)号：US20110098625A1

公开(公告)日：2011-04-28

申请号：US12994383

申请日：2008-05-26

申请人： Pietro Masala ,  Mauro Suffritti ,  Anders Wallenborg ,  Thomas Gebhart

发明人： Pietro Masala ,  Mauro Suffritti ,  Anders Wallenborg ,  Thomas Gebhart

IPC分类号： A61M1/34

CPC分类号： A61M1/3639 ,  A61M1/342 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M2205/3331 ,  G06F19/00

摘要： In a hemodiafiltration apparatus, a control and command unit (11) halts a replacement fluid supply pump (8) and contemporaneously modifies the control mode of a blood pump (1) passing from a control based on the pump velocity to a control based on the blood pressure measured by a sensor (12) arranged downstream of a hemodiafilter (3). The aim is to prevent risks due to excessive hemo-concentration in the blood circuit between the ultrafiltration zone and the infusion zone.

摘要翻译： 在血液透析过滤装置中，控制和指令单元（11）停止替换流体供应泵（8），同时将基于泵速度的控制通过的血液泵（1）的控制模式同时修改为基于 通过布置在血液透析滤器（3）下游的传感器（12）测量的血压。 目的是防止超滤区和输液区血液循环过度血液浓度过高所引起的风险。

公开(公告)号：US08545427B2

公开(公告)日：2013-10-01

申请号：US13124316

申请日：2009-10-12

申请人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

发明人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

IPC分类号： A61M37/00 ,  C02F1/44 ,  F04B43/08

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M2205/50

摘要： A blood treatment apparatus, including a blood treatment unit configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid, a pair of fluid pumps configured to pass blood treatment fluid through the blood treatment unit, a pair of blood pumps configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel, each blood pump including a pump chamber and a flexible member separating the pumping chamber into a first blood accumulating container and a second working fluid accumulating container where the flexible member is configured to vary a volume relationship between the first and the second accumulation containers. A control unit and a measuring device are configured to emit a feedback signal indicative of the amount of working fluid received into, or discharged from at least one of the second accumulation containers whereby the pumped mass or volume of working fluid is determined by the control unit at an arbitrary position of the flexible member.

摘要翻译： 一种血液处理装置，包括：血液处理单元，其构造为接收未经处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理流体;一对流体泵，被配置为使血液处理液通过所述血液处理单元， 被配置为从血液源提取未处理的血液的血液泵，将提取的血液通过血液处理单元并将处理的血液输送到目标血管，每个血液泵包括泵室和将泵送室分离成第一血液积聚的柔性构件 容器和第二工作流体积聚容器，其中柔性构件构造成改变第一和第二积聚容器之间的体积关系。 控制单元和测量装置被配置为发出指示接收到或从第二积聚容器中的至少一个排出的工作流体的量的反馈信号，由此泵送的质量或体积的工作流体由控制单元确定 在柔性构件的任意位置。

公开(公告)号：US08485999B2

公开(公告)日：2013-07-16

申请号：US13124258

申请日：2009-10-12

申请人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

发明人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

IPC分类号： A61M37/00 ,  C02F1/44

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M2205/50

摘要： A blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair of blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Flow measurement device which determines at least one blood flow parameter reflecting an average flow in relation to the blood treatment unit during a well-defined period of operation of the apparatus, for example while completing one operation cycle. The at least one blood flow parameter is determined based on a difference between (i) a first amount of fresh blood treatment fluid received into the blood treatment unit, and (ii) a second amount of used blood treatment fluid emitted from the blood treatment unit during another well-defined period.

摘要翻译： 血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 流量测量装置，例如在完成一个操作周期期间，确定在装置的操作的良好定义的周期期间反映相对于血液处理单元的平均流量的至少一个血流参数。 基于（i）接收到血液处理单元中的第一量的新鲜血液处理液和（ii）从血液处理单元发出的第二量的使用的血液处理液的差异来确定至少一个血流参数 在另一个明确的时期。

公开(公告)号：US08647290B2

公开(公告)日：2014-02-11

申请号：US12994383

申请日：2008-05-26

申请人： Pietro Masala ,  Mauro Suffritti ,  Anders Wallenborg ,  Thomas Gebhart

发明人： Pietro Masala ,  Mauro Suffritti ,  Anders Wallenborg ,  Thomas Gebhart

IPC分类号： A61M1/34 ,  A61M1/14 ,  A61M1/16 ,  A61M5/142

CPC分类号： A61M1/3639 ,  A61M1/342 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M2205/3331 ,  G06F19/00

摘要： In a hemodiafiltration apparatus, a control and command unit (11) halts a replacement fluid supply pump (8) and contemporaneously modifies the control mode of a blood pump (1) passing from a control based on the pump velocity to a control based on the blood pressure measured by a sensor (12) arranged downstream of a hemodiafilter (3). The aim is to prevent risks due to excessive hemoconcentration in the blood circuit between the ultrafiltration zone and the infusion zone.

摘要翻译： 在血液透析过滤装置中，控制和指令单元（11）停止替换流体供应泵（8），同时将基于泵速度的控制通过的血液泵（1）的控制模式同时修改为基于 通过布置在血液透析滤器（3）下游的传感器（12）测量的血压。 目的是防止超滤区域和输注区域之间的血液循环过度血液浓缩引起的风险。

公开(公告)号：US20110201989A1

公开(公告)日：2011-08-18

申请号：US13124316

申请日：2009-10-12

申请人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

发明人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

IPC分类号： A61M1/16 ,  B01D33/70

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M2205/50

摘要： A blood treatment apparatus, including a blood treatment unit configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid, a pair of fluid pumps configured to pass blood treatment fluid through the blood treatment unit, a pair of blood pumps configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel, each blood pump including a pump chamber and a flexible member separating the pumping chamber into a first blood accumulating container and a second working fluid accumulating container where the flexible member is configured to vary a volume relationship between the first and the second accumulation containers. A control unit and a measuring device are configured to emit a feedback signal indicative of the amount of working fluid received into, or discharged from at least one of the second accumulation containers whereby the pumped mass or volume of working fluid is determined by the control unit at an arbitrary position of the flexible member.

摘要翻译： 一种血液处理装置，包括：血液处理单元，其构造为接收未经处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理流体;一对流体泵，被配置为使血液处理液通过所述血液处理单元， 被配置为从血液源提取未处理的血液的血液泵，将提取的血液通过血液处理单元并将处理的血液输送到目标血管，每个血液泵包括泵室和将泵送室分离成第一血液积聚的柔性构件 容器和第二工作流体积聚容器，其中柔性构件构造成改变第一和第二积聚容器之间的体积关系。 控制单元和测量装置被配置为发出指示接收到或从第二积聚容器中的至少一个排出的工作流体的量的反馈信号，由此泵送的质量或体积的工作流体由控制单元确定 在柔性构件的任意位置。