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公开(公告)号：US07867992B2
公开(公告)日：2011-01-11
申请号：US11655589
申请日：2007-01-19
申请人： Holger Zimmermann , Rudolf Schohe-Loop , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Daniela Paulsen , Thomas Roelle , Johannes Koebberling , Marcus Bauser
发明人： Holger Zimmermann , Rudolf Schohe-Loop , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Daniela Paulsen , Thomas Roelle , Johannes Koebberling , Marcus Bauser
IPC分类号： A01N43/62 , A61K31/55 , C07D413/00
CPC分类号： C07D215/56 , C07D401/04
摘要： The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US07569563B2
公开(公告)日：2009-08-04
申请号：US12006086
申请日：2007-12-28
申请人： Rudolf Schohe-Loop , Holger Zimmermann , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner
发明人： Rudolf Schohe-Loop , Holger Zimmermann , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner
IPC分类号： A61K31/5365 , A61K31/496 , C07D215/56 , C07D498/061 , A61K31/551
CPC分类号： C07D215/56
摘要： The invention relates to substituted quinolones of formula (I) and to methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular against cytomegaloviruses.
摘要翻译： 本发明涉及式（I）的取代喹诺酮及其制备方法及其用于生产药物的用途，所述药物用于治疗和/或预防疾病，特别是用作抗病毒剂，特别是用于巨细胞病毒的疾病。
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公开(公告)号：US07977349B2
公开(公告)日：2011-07-12
申请号：US12188940
申请日：2008-08-08
申请人： Chantal Fuerstner , Kai Thede , Holger Zimmermann , David Brueckner , Kerstin Henninger , Dieter Lang , Rudolf Schohe-Loop
发明人： Chantal Fuerstner , Kai Thede , Holger Zimmermann , David Brueckner , Kerstin Henninger , Dieter Lang , Rudolf Schohe-Loop
IPC分类号： A61K31/4709 , A61P31/12 , C07D401/10 , C07D498/10 , C07D401/14
CPC分类号： C07D401/04 , C07D401/14 , C07D471/10
摘要： The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮类及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20080261964A1
公开(公告)日：2008-10-23
申请号：US12006086
申请日：2007-12-28
申请人： Rudolf Schohe-Loop , Holger Zimmermann , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner
发明人： Rudolf Schohe-Loop , Holger Zimmermann , Kerstin Henninger , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner
IPC分类号： A61K31/5383 , C07D401/02 , A61K31/496 , A61P31/12 , C07D265/38
CPC分类号： C07D215/56
摘要： The invention relates to substituted quinolones of formula (I) and to methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular against cytomegaloviruses.
摘要翻译： 本发明涉及式（I）的取代喹诺酮及其制备方法及其用于生产药物的用途，所述药物用于治疗和/或预防疾病，特别是用作抗病毒剂，特别是用于巨细胞病毒的疾病。
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公开(公告)号：US20090181996A1
公开(公告)日：2009-07-16
申请号：US12188940
申请日：2008-08-08
申请人： Chantal Fuerstner , Kai Thede , Holger Zimmermann , David Brueckner , Kerstin Henninger , Dieter Lang , Rudolf Schohe-Loop
发明人： Chantal Fuerstner , Kai Thede , Holger Zimmermann , David Brueckner , Kerstin Henninger , Dieter Lang , Rudolf Schohe-Loop
IPC分类号： A61K31/4709 , C07D401/10 , C07D471/10 , C07D498/10 , C07D401/14 , A61P31/12
CPC分类号： C07D401/04 , C07D401/14 , C07D471/10
摘要： The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮类及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20070293478A1
公开(公告)日：2007-12-20
申请号：US11655589
申请日：2007-01-19
申请人： Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
发明人： Holger Zimmermann , Rudolph Schohe-loop , Kerstin Henninger , Daniela Paulsen , Thomas Roelle , Dieter Lang , Kai Thede , Chantal Fuerstner , David Brueckner , Johannes Koebberling , Marcus Bauser
IPC分类号： A61K31/497 , A61K31/5377 , A61K31/5513 , A61P31/22 , C07D243/08 , C07D401/02 , C07D413/14
CPC分类号： C07D215/56 , C07D401/04
摘要： The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
摘要翻译： 本发明涉及取代的喹诺酮及其制备方法，以及它们用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US07767704B2
公开(公告)日：2010-08-03
申请号：US10594343
申请日：2005-03-11
申请人： Holger Zimmermann , David Brueckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Joerg Keldenich , Dieter Lang , Martin Radtke
发明人： Holger Zimmermann , David Brueckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Joerg Keldenich , Dieter Lang , Martin Radtke
IPC分类号： A61K31/4164 , C07D233/54
CPC分类号： C07D233/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
摘要翻译： 本发明涉及式（I）的取代的咪唑及其制备方法，用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途 特别是用作抗病毒剂，特别是抗巨细胞病毒。
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公开(公告)号：US07919489B2
公开(公告)日：2011-04-05
申请号：US11894307
申请日：2007-08-20
申请人： Holger Zimmermann , David Brueckner , Kerstin Henninger , Ulrich Rosentreter , Martin Hendrix , Joerg Keldenich , Dieter Lang , Martin Radtke , Daniela Paulsen , Armin Kern
发明人： Holger Zimmermann , David Brueckner , Kerstin Henninger , Ulrich Rosentreter , Martin Hendrix , Joerg Keldenich , Dieter Lang , Martin Radtke , Daniela Paulsen , Armin Kern
IPC分类号： A61P31/12 , A61K31/4178 , A61K31/4164 , C07D401/12 , C07D233/90
CPC分类号： C07D233/90 , C07D401/12
摘要： The invention relates to heterocyclylamide-substituted imidazoles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
摘要翻译： 本发明涉及杂环基酰胺取代的咪唑及其制备方法，它们用于治疗和/或预防疾病及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用于 作为抗病毒剂，特别是针对巨细胞病毒。
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公开(公告)号：US08410090B2
公开(公告)日：2013-04-02
申请号：US11988911
申请日：2006-07-01
IPC分类号： A61P31/12 , A61K31/38 , A61K31/40 , C07D401/12 , C07D409/12 , C07D417/12
CPC分类号： C07D409/12 , C07D401/12 , C07D417/12
摘要： The invention relates to heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and processes for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
摘要翻译： 本发明涉及杂环酰胺取代的噻唑，吡咯和噻吩及其制备方法，含有它们的药物组合物及其用于治疗和/或预防疾病的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒 。
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