专利检索 ap:("Rumin Zhang" OR "Bruce A. Malcolm" OR "Brian M. Beyer" OR "F. George Njoroge" OR "James P. Durkin" OR "William T. Windsor") AND inv:"James P. Durkin" 第 1 页

1.

发明授权
Peptide substrates for HCV NS3 protease assays 有权
标题翻译：用于HCV NS3蛋白酶测定的肽底物

公开(公告)号：US06251583B1

公开(公告)日：2001-06-26

申请号：US09288391

申请日：1999-04-08

申请人： Rumin Zhang , Bruce A. Malcolm , Brian M. Beyer , F. George Njoroge , James P. Durkin , William T. Windsor

发明人： Rumin Zhang , Bruce A. Malcolm , Brian M. Beyer , F. George Njoroge , James P. Durkin , William T. Windsor

IPC分类号： C12Q170

CPC分类号： C07K14/005 , C12N2770/24222 , C12Q1/37 , C12Q1/70 , G01N2333/18

摘要： Novel chromogenic, fluorogenic and fluorescence polarization substrates which are useful in HCV NS3 protease and inhibitor assays.

摘要翻译： 新的显色，荧光和荧光偏振底物，可用于HCV NS3蛋白酶和抑制剂测定。

2.

发明授权
Peptide substrates of a proteolytic ADAM33 polypeptide and assays using the same 失效

公开(公告)号：US07067273B2

公开(公告)日：2006-06-27

申请号：US10741205

申请日：2003-12-19

申请人： Rumin Zhang , Jun Zou , Feng X. Zhu , James P. Durkin , William T. Windsor , Shelby P. Umland

发明人： Rumin Zhang , Jun Zou , Feng X. Zhu , James P. Durkin , William T. Windsor , Shelby P. Umland

IPC分类号： C07K7/06 , C07K7/08 , C12Q1/37

CPC分类号： C07K7/06 , A61K38/00 , C07K7/08 , C12N9/6489 , C12Q1/37 , G01N2500/00

摘要： The present invention discloses peptide substrates of a proteolytic ADAM33 polypeptide. The present invention also discloses methods of identifying additional substrates of a proteolytic ADAM33 polypeptide. Furthermore, the present invention discloses methods of identifying compounds that inhibit the proteolytic activity of a proteolytic ADAM33 polypeptide.