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    Tissue-penetrating guidewires with shaped tips, and associated systems and methods
    1.
    发明授权
    Tissue-penetrating guidewires with shaped tips, and associated systems and methods 失效
    具有形状尖端的组织穿透导丝，以及相关的系统和方法

    公开(公告)号：US08308723B2

    公开(公告)日：2012-11-13

    申请号：US12576928

    申请日：2009-10-09

    申请人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    发明人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0063 ,  Y10T29/49002

    摘要： Tissue-penetrating guidewires with shaped tips, and associated systems and methods are disclosed. A patient treatment system in accordance with one embodiment of the disclosure includes a tissue-penetrating guidewire that in turn includes a flexible segment having a distal portion and a proximal portion. The flexible segment is elongated along an elongation axis. A penetrating member is positioned at the distal portion and includes at least one blade segment having a tapered outer peripheral surface and an adjacent generally sharp edge. The blade segment extends to a distal end of the penetrating member to form a generally blunt tip. In operation, the guidewire can be connected to an electrical current source to deliver high frequency current to the penetrating member.

    摘要翻译： 具有成形尖端的组织穿透导丝以及相关系统和方法被公开。 根据本公开的一个实施例的患者治疗系统包括组织穿透导丝，该导丝又包括具有远端部分和近端部分的柔性部分。 柔性段沿伸长轴伸长。 穿透构件定位在远侧部分并且包括至少一个具有锥形外周表面和相邻的大致锋利边缘的刀片段。 刀片段延伸到穿透构件的远端以形成通常钝的末端。 在操作中，导丝可以连接到电流源以将高频电流传送到穿透构件。

    SYSTEMS AND METHODS FOR TRANSEPTAL CARDIAC PROCEDURES, INCLUDING ADJUSTABLE, SEPARABLE GUIDEWIRES
    2.
    发明申请
    SYSTEMS AND METHODS FOR TRANSEPTAL CARDIAC PROCEDURES, INCLUDING ADJUSTABLE, SEPARABLE GUIDEWIRES 审中-公开
    用于过渡心脏手术的系统和方法，包括可调节的可分离指南

    公开(公告)号：US20110218503A1

    公开(公告)日：2011-09-08

    申请号：US13038946

    申请日：2011-03-02

    申请人： Ryan E. Kaveckis ,  Larry B. Kulesa ,  David C. Auth

    发明人： Ryan E. Kaveckis ,  Larry B. Kulesa ,  David C. Auth

    IPC分类号： A61M25/00

    CPC分类号： A61M25/00

    摘要： Systems and methods for transeptal cardiac procedures are disclosed. A patient treatment device in accordance with a particular embodiment includes an elongated intravascular guidewire that includes a first branch and a second branch fixedly secured relative to the first branch at a first location and releasably secured relative to the first branch at a second location. At least one of the first and second branches is movable relative to the other between a first position in which the first and second branches form a closed shape, and a second position in which the first and second branches form an open shape. A controller can be operatively coupled to the first and second branches to control (e.g., in a fixed increment manner or a continuously variable manner) a distance between a portion of the first branch and a portion of the second branch while the first and second branches form the closed shape.

    摘要翻译： 公开了用于经心脏心脏手术的系统和方法。 根据特定实施例的患者治疗装置包括细长的血管内导丝，其包括在第一位置处相对于第一分支固定地固定的第一分支和第二分支，并且在第二位置处相对于第一分支可释放地固定。 第一和第二分支中的至少一个在第一和第二分支形成封闭形状的第一位置和第一和第二分支形成开放形状的第二位置之间相对于另一分支可移动。 控制器可以可操作地耦合到第一和第二分支以在第一和第二分支的一部分之间的距离（例如，以固定递增方式或连续可变的方式）控制第一分支的一部分与第二分支的一部分之间的距离， 形成封闭形状。

    TISSUE-PENETRATING GUIDEWIRES WITH SHAPED TIPS, AND ASSOCIATED SYSTEMS AND METHODS
    5.
    发明申请
    TISSUE-PENETRATING GUIDEWIRES WITH SHAPED TIPS, AND ASSOCIATED SYSTEMS AND METHODS 失效
    具有形状提示的组织穿刺指南及相关系统和方法

    公开(公告)号：US20110087211A1

    公开(公告)日：2011-04-14

    申请号：US12576928

    申请日：2009-10-09

    申请人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    发明人： Larry B. Kulesa ,  David C. Auth ,  Ryan E. Kaveckis

    IPC分类号： A61B18/18 ,  H01S4/00 ,  G05B9/02 ,  G05B11/01

    CPC分类号： A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0063 ,  Y10T29/49002

    摘要： Tissue-penetrating guidewires with shaped tips, and associated systems and methods are disclosed. A patient treatment system in accordance with one embodiment of the disclosure includes a tissue-penetrating guidewire that in turn includes a flexible segment having a distal portion and a proximal portion. The flexible segment is elongated along an elongation axis. A penetrating member is positioned at the distal portion and includes at least one blade segment having a tapered outer peripheral surface and an adjacent generally sharp edge. The blade segment extends to a distal end of the penetrating member to form a generally blunt tip. In operation, the guidewire can be connected to an electrical current source to deliver high frequency current to the penetrating member.

    摘要翻译： 具有成形尖端的组织穿透导丝以及相关系统和方法被公开。 根据本公开的一个实施例的患者治疗系统包括组织穿透导丝，该导丝又包括具有远端部分和近端部分的柔性部分。 柔性段沿伸长轴伸长。 穿透构件定位在远侧部分并且包括至少一个具有锥形外周表面和相邻的大致锋利边缘的刀片段。 刀片段延伸到穿透构件的远端以形成通常钝的末端。 在操作中，导丝可以连接到电流源以将高频电流传送到穿透构件。

    HEMOSTATIC SPARK EROSION TISSUE TUNNEL GENERATOR WITH INTEGRAL TREATMENT PROVIDING VARIABLE VOLUMETRIC NECROTIZATION OF TISSUE
    7.
    发明申请
    HEMOSTATIC SPARK EROSION TISSUE TUNNEL GENERATOR WITH INTEGRAL TREATMENT PROVIDING VARIABLE VOLUMETRIC NECROTIZATION OF TISSUE 失效
    具有综合治疗的HEMOSTATIC SPARK EROSION TISSUE TUNNEL发生器提供组织的可变体积分解

    公开(公告)号：US20090118729A1

    公开(公告)日：2009-05-07

    申请号：US11936748

    申请日：2007-11-07

    申请人： David C. Auth ,  Alexander Lebedev ,  Michael J. Connolly

    发明人： David C. Auth ,  Alexander Lebedev ,  Michael J. Connolly

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B8/12 ,  A61B18/1815 ,  A61B2018/00791 ,  A61B2018/1213 ,  A61B2018/1472 ,  A61B2018/1475 ,  A61B2090/3784 ,  A61B2218/002 ,  A61B2218/007

    摘要： A catheter for insertion into and treatment of tissue in a patient comprises a radio frequency (RF) electrode having an elongated body that conducts electrical RF energy to a conductive tip. An insulating sleeve surrounding the elongated body prevents leakage of RF energy from the elongated body when the catheter is being inserted into the tissue of the patient. In a first mode of operation, the conductive tip is exposed outside the insulating sleeve and the RF electrode delivers first RF energy capable of producing sparks that erode the tissue of the patient and create a tunnel through which the catheter can advance into the tissue of the patient. In a second mode of operation, the insulating sleeve is retracted to expose a portion of the RF electrode. Second RF energy is delivered to the volume of tissue around the catheter to necrotize the tissue by heating without producing sparks.

    摘要翻译： 用于插入和治疗患者组织的导管包括射频（RF）电极，其具有将电RF能量传导到导电尖端的细长主体。 围绕细长主体的绝缘套管防止当导管插入到患者组织中时，来自细长体的RF能量的泄漏。 在第一操作模式中，导电尖端暴露在绝缘套管外部，并且RF电极提供能够产生火花的第一RF能量，该火花侵蚀患者的组织并产生通道，导管可穿过该通道进入组织中 患者。 在第二操作模式中，绝缘套管缩回以暴露RF电极的一部分。 将第二RF能量传递到导管周围的组织体积，以通过加热而不产生火花来坏死组织。

    Systems and methods for securing cardiovascular tissue
    8.
    发明授权
    Systems and methods for securing cardiovascular tissue 失效
    用于确保心血管组织的系统和方法

    公开(公告)号：US07257450B2

    公开(公告)日：2007-08-14

    申请号：US11004634

    申请日：2004-12-02

    申请人： David C. Auth ,  Dean T. Corcoran ,  Mark A. Tempel ,  Joseph E. Eichinger

    发明人： David C. Auth ,  Dean T. Corcoran ,  Mark A. Tempel ,  Joseph E. Eichinger

    IPC分类号： A61N1/05 ,  A61N1/18

    CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61N1/06 ,  A61N1/403

    摘要： Methods and systems for securing tissues, e.g., cardiovascular tissues, are disclosed. A method in accordance with one embodiment of the invention includes inserting a portion of a catheter into an opening between a first portion of cardiovascular tissue and a second portion of cardiovascular tissue. The method can further include drawing the first and second portions of the cardiovascular tissue into contact with each other by drawing a vacuum in a region adjacent to the first and second portions of cardiovascular tissue via the catheter while the catheter is positioned between the first and second portions. The tissue portions can be fused by heating the tissue from within the opening, e.g., via radio frequency energy. This technique, and associated catheter system, can be used to close a patent foramen ovale or other openings in cardiovascular tissue.

    摘要翻译： 公开了用于确保组织例如心血管组织的方法和系统。 根据本发明的一个实施例的方法包括将导管的一部分插入心血管组织的第一部分和心血管组织的第二部分之间的开口中。 该方法可以进一步包括通过在导管位于第一和第二部分之间的同时在与心血管组织的第一和第二部分相邻的区域中抽取真空而将心血管组织的第一和第二部分相互接触 部分。 组织部分可以通过例如通过射频能量从开口内加热组织来融合。 该技术和相关的导管系统可用于闭合心脏组织中的卵孔或其他开口的专利。

    Multipolar electrosurgical device and method
    9.
    发明授权
    Multipolar electrosurgical device and method 失效
    多极电外科装置及方法

    公开(公告)号：US4532924A

    公开(公告)日：1985-08-06

    申请号：US373652

    申请日：1982-04-30

    申请人： David C. Auth ,  Eric A. Opie ,  Dale M. Lawrence

    发明人： David C. Auth ,  Eric A. Opie ,  Dale M. Lawrence

    IPC分类号： A61B17/00 ,  A61B18/14 ,  A61M3/02 ,  A61B17/39

    CPC分类号： A61B18/14 ,  A61B18/1402 ,  A61B2017/00292 ,  A61B2018/1497 ,  A61B2018/1861 ,  A61B2218/002 ,  A61M3/0279

    摘要： A multipolar electrosurgical device is described for use in neurosurgery or through the channel of an endoscope or other precision surgery procedures. The device is formed with an insulative probe body, which, in the described embodiment, is sized to pass through a channel of an endoscope to enable the electrocoagulation of blood vessels such as may be needed in the treatment of a gastrointestinal ulcer. The probe body is provided with electrically separate conductors which are formed of a plurality of electrodes distributed over the peripheral surface of the probe body. The electrically separate conductors are so sized in width W and spaced from each other by a distance S as to establish a ratio of W:S which enables effective bipolar treatment of tissue independent of probe body orientation relative to the tissue and without sticking of the probe body to coagulated material. A plurality of at least six electrodes which can form six bipolar electric fields are formed which in one embodiment are aligned longitudinally on the probe body. The electrodes extend onto the probe body's distal end to provide an omnidirectionally effective electrosurgical device. A central conductive wash channel is provided for electrical connection to a set of electrodes at the distal end of the probe body while also providing a passage for fluid to enhance the visibility of the target area for subsequent precise electrocoagulation of the bleeding site. Several embodiments are shown and described.

    摘要翻译： 描述了用于神经外科手术或通过内窥镜通道或其他精密手术程序的多极电外科装置。 该装置形成有绝缘探针体，其在所描述的实施例中的尺寸适于穿过内窥镜的通道，使得能够电凝凝血管，例如可能需要治疗胃肠溃疡。 探针体设置有电分离的导体，其由分布在探针主体的外周表面上的多个电极形成。 电分离的导体的宽度尺寸设置为W，并且彼此间隔开距离S，以便建立W：S的比率，这使得能够相对于组织而独立于探头本体取向的组织进行有效的双极治疗，并且不粘附探针 身体凝固材料。 形成可形成六个双极电场的多个至少六个电极，其在一个实施例中在探针主体上纵向排列。 电极延伸到探针主体的远端，以提供全向有效的电外科装置。 提供中心导电清洗通道用于电连接到在探针主体的远端处的一组电极，同时还为流体提供通道以增强目标区域的可视性，以便随后精确地凝固出血部位。 显示和描述了几个实施例。

    Method and apparatus for removal of enclosed abnormal deposits
    10.
    发明授权
    Method and apparatus for removal of enclosed abnormal deposits 失效
    去除封闭异常沉积物的方法和装置

    公开(公告)号：US4445509A

    公开(公告)日：1984-05-01

    申请号：US345656

    申请日：1982-02-04

    申请人： David C. Auth

    发明人： David C. Auth

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61M1/00 ,  A61B17/32

    CPC分类号： A61B17/320758 ,  A61B17/22031 ,  A61B2017/22074 ,  A61B2217/005 ,  A61B2217/007

    摘要： A device for safe removal of abnormal deposits, primarily in the human body, where differential cutting properties provide for fracture of hard matter while safely preserving soft tissue. The device includes a rotating cutting tool having spirally shaped cutting flutes having hardness-differential cutting properties. The tool is driven from outside the body by means of a flexible drive shaft at greater than 2000 revolutions per minute. A channel is incorporated in the drive shaft for adding or removing chemical matter from the internal body space to provide systematic removal of cutting debris from abnormal deposits. The cutting tool has fluid ports which communicate with the drive shaft channel. The fluid ports may be at the nose of the tool as well as around its cicumference. In the latter instance, the ports extend from in front of a cutting flute into a center cavity with a circumferential component so that rotation tends to force blood into these ports. External mass transfer machines aid in injecting or withdrawing material, such as cutting debris. Auxiliary instrumentation, such as fluoroscopy and pressure measuring apparatus, are helpful in the clinical procedure. Multiple operational cycles are easily implemented to gradually dissect the deposit while periodically reestablishing physiological viability, such as blood flow in vessels.

    摘要翻译： 一种用于安全去除异常沉积物的装置，主要在人体中，其中不同的切割性质提供硬质物质的断裂，同时安全地保存软组织。 该装置包括具有硬度差分切割性能的螺旋状切割槽的旋转切削工具。 该工具通过柔性驱动轴以大于2000转每分钟从外部驱动。 一个通道被结合在驱动轴中，用于从内部空间添加或除去化学物质，以提供系统地从异常沉积物中去除切屑。 切割工具具有与驱动轴通道连通的流体端口。 流体端口可以在工具的鼻子处以及其周围。 在后一种情况下，端口从切割槽的前面延伸到具有周向部件的中心空腔中，使得旋转倾向于迫使血液进入这些端口。 外部传质机器有助于注入或取出材料，如切割碎屑。 辅助仪器，如荧光透视和压力测量仪器，有助于临床过程。 容易实施多个操作周期，以逐步解剖沉积物，同时周期性地重新建立生理活力，如血管中的血流。