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    Sample carrier for optical measurements
    2.
    发明授权
    Sample carrier for optical measurements 有权

    公开(公告)号：US11307196B2

    公开(公告)日：2022-04-19

    申请号：US16098893

    申请日：2017-05-11

    Applicant: S.D. SIGHT DIAGNOSTICS LTD.

    Inventor： Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel ,  Amir Zait ,  Sharon Pecker ,  Trevor Ruggiero

    IPC: G01N33/50 ,  G01N21/31 ,  G01N21/59 ,  G01N21/64 ,  G01N21/03

    Abstract: Apparatus and methods are described for determining a property of a biological sample. A sample carrier (22) includes one or more sample chambers (40) that define at least a first region (42) and a second region (44), the height of the one or more sample chambers varying between the first and second regions in a predefined manner. A computer processor (28) receives data relating to a first optical measurement that is performed upon a portion of the sample that is disposed within the first region, receives data relating to a second optical measurement that is performed upon a portion of the sample that is disposed within the second region, and determines the property of the sample by using a relationship between the first optical measurement, the second optical measurement, and the predefined variation in height between the regions. Other applications are also described.

    SAMPLE CARRIER FOR OPTICAL MEASUREMENTS
    3.
    发明申请
    SAMPLE CARRIER FOR OPTICAL MEASUREMENTS 有权

    公开(公告)号：US20210072226A1

    公开(公告)日：2021-03-11

    申请号：US17082483

    申请日：2020-10-28

    Applicant: S.D. SIGHT DIAGNOSTICS LTD.

    Inventor： Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel ,  Amir Zait ,  Sharon Pecker ,  Trevor Ruggiero

    IPC: G01N33/50 ,  G01N21/31 ,  G01N21/59 ,  G01N21/64 ,  G01N21/03

    Abstract: Apparatus and methods are described including placing a sample into a sample carrier that comprises a plurality of regions having upper and lower surfaces, having respective heights that are different from each other, and being configured such that cells form a monolayer, the monolayer within respective regions of the sample carrier having respective, different densities from each other, due to the respective regions of the sample carrier having respective heights that are different from each other. Microscopic images are acquired of each of the plurality of regions. Measurements are performed upon cell types that have a relatively high density upon microscopic images of a region of the sample chamber having a relatively low height, and measurements are performed upon cell types that have a relatively low density upon microscopic images of a region of the sample chamber having a relatively great height. Other applications are also described.

    SAMPLE CARRIER FOR OPTICAL MEASUREMENTS
    8.
    发明申请
    SAMPLE CARRIER FOR OPTICAL MEASUREMENTS 有权

    公开(公告)号：US20210041417A1

    公开(公告)日：2021-02-11

    申请号：US17083647

    申请日：2020-10-29

    Applicant: S.D. SIGHT DIAGNOSTICS LTD

    Inventor： Joseph Joel Pollak ,  Sarah Levy Schreier ,  Yochay Shlomo Eshel ,  Amir Zait ,  Sharon Pecker ,  Trevor Ruggiero

    IPC: G01N33/50 ,  G01N21/31 ,  G01N21/59 ,  G01N21/64 ,  G01N21/03

    Abstract: Apparatus and methods are described for determining a property of a biological sample. A sample carrier includes a glass substrate configured to define a first surface of a sample chamber that is configured to receive the sample, and a plastic substrate configured to define a second surface of the sample chamber. The height of the sample chamber at each location within the sample chamber is defined by a gap between the first surface and the second surface. An adhesive adheres the glass substrate to the plastic substrate. The plastic substrate is shaped such that the sample chamber defines a first region and a second region, with the sample chamber defining a predefined variation in height between the first region and the second region. Other applications are also described.

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