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公开(公告)号：US20210325373A1
公开(公告)日：2021-10-21
申请号：US17360503
申请日：2021-06-28
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Amir Zait , Arnon Houri Yafin , Dan Gluck , Sharon Pecker , Yochay Shlomo Eshel , Sarah Levy Schreier , Joseph Joel Pollak
IPC: G01N33/50 , G01N33/49 , G01N33/72 , G01N15/06 , G01N33/569
Abstract: Apparatus and methods are described including measuring hematocrit within a blood sample, by performing a first measurement on a first portion of the blood sample. Mean corpuscular volume in the blood sample is measured, by performing a second measurement on a second portion of the blood sample, the second portion being diluted with respect to the first portion. A red blood cell count per unit volume within the blood sample is determined by dividing the hematocrit measured within the first portion by the mean corpuscular volume measured within the second portion. Other applications are also described.
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公开(公告)号：US11914133B2
公开(公告)日：2024-02-27
申请号：US17568858
申请日：2022-01-05
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo Eshel , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
CPC classification number: G02B21/367 , G01N21/8851 , G02B21/365 , G06T7/0012 , G06V20/693 , G06V20/698 , G01N2021/8887 , G06T2207/10056 , G06T2207/30024 , G06T2207/30101
Abstract: Apparatus and methods are described for analyzing a bodily sample. A microscope system acquires one or more microscope images of the bodily sample. A computer processor identifies elements as being candidates of a given entity, in the one or more images. At least one sample-informative feature, relating to a characteristic of the candidates of the given entity in the sample as a whole, is extracted from the one or more images. A characteristic of the sample is determined at least partially based upon the sample-informative feature, and an output is generated in response thereto. Other applications are also described.
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公开(公告)号：US20200249458A1
公开(公告)日：2020-08-06
申请号：US16851410
申请日：2020-04-17
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo ESHEL , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
Abstract: Apparatus and methods are described including acquiring microscopic images of a blood sample, and identifying deformed red blood cells within the microscopic images. A degree of red blood cell deformity within the sample is determined, at least partially based upon the identified deformed red blood cells. A sample-informative parameter that is indicative of a characteristic of the blood sample as a whole is determined, at least partially based upon the degree of red blood cell deformity within the sample. Other applications are also described.
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公开(公告)号：US12189112B2
公开(公告)日：2025-01-07
申请号：US17783924
申请日：2020-12-10
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yonatan Halperin , Dan Gluck , Noam Yorav-Raphael , Yochay Shlomo Eshel , Sarah Levy , Joseph Joel Pollak
Abstract: Apparatus and methods are described for use with a blood sample. Using a microscope (24), three images of a microscopic imaging field of the blood sample are acquired, each of the images being acquired using respective, different imaging conditions, and the first one of the three images being acquired under violet-light brightfield imaging. Using at least one computer processor (28), an artificial color microscopic image of the microscopic imaging field is generated, by mapping the first one of the three images to a red channel of the artificial color microscopic image, mapping a second one of the three images to a second color channel of the artificial color microscopic image, and mapping a third one of the three images to a third color channel of the artificial color microscopic image. Other applications are also described.
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公开(公告)号：US11199690B2
公开(公告)日：2021-12-14
申请号：US16851410
申请日：2020-04-17
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo Eshel , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
Abstract: Apparatus and methods are described including acquiring microscopic images of a blood sample, and identifying deformed red blood cells within the microscopic images. A degree of red blood cell deformity within the sample is determined, at least partially based upon the identified deformed red blood cells. A sample-informative parameter that is indicative of a characteristic of the blood sample as a whole is determined, at least partially based upon the degree of red blood cell deformity within the sample. Other applications are also described.
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Patent Agency Ranking
公开(公告)号：US12174175B2
公开(公告)日：2024-12-24
申请号：US17082615
申请日：2020-10-28
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Amir Zait , Arnon Houri Yafin , Dan Gluck , Sharon Pecker , Yochay Shlomo Eshel , Sarah Levy Schreier , Joseph Joel Pollak
Abstract: Apparatus and methods are described including placing a first portion of a biological sample into a source sample portion chamber of a sample carrier, and placing a second portion of the biological sample into a diluted sample portion chamber. The second portion of the biological sample is diluted with respect to the first portion of the biological sample. Using an optical measurement device, a bulk-level measurand of the sample that relates to a parameter of the biological sample as a whole is measured, by performing a measurement upon the first portion of the biological sample. Microscopic images of the second portion of the biological sample are acquired. Other applications are also described.
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公开(公告)号：US11796788B2
公开(公告)日：2023-10-24
申请号：US17490767
申请日：2021-09-30
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo Eshel , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
CPC classification number: G02B21/367 , G01N21/8851 , G02B21/365 , G06T7/0012 , G06V20/693 , G06V20/698 , G01N2021/8887 , G06T2207/10056 , G06T2207/30024 , G06T2207/30101
Abstract: Apparatus and methods are described for analyzing a bodily sample. One or more microscope images of the bodily sample are acquired. Using at least one computer processor at least one sample-informative feature that is indicative of a characteristic of the bodily sample is extracted from the images. Based upon the sample-informative feature, the computer processor determines that there is a defect associated with the bodily sample, and determines a source of the defect. Other applications are also described.
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公开(公告)号：US11262571B2
公开(公告)日：2022-03-01
申请号：US16851686
申请日：2020-04-17
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo Eshel , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
Abstract: Apparatus and methods are described including staining a blood sample with one or more stains. A plurality of microscopic images of the stained blood sample are acquired, using a microscope. Staining-quality parameters for respective microscopic images are determined, using a computer processor, the staining-quality parameters being indicative of a quality of the staining within each of the respective microscopic images. An action is performed by the computer processor, based upon the staining-quality parameters of the respective microscopic images. Other applications are also described.
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公开(公告)号：US10663712B2
公开(公告)日：2020-05-26
申请号：US16657473
申请日：2019-10-18
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Yochay Shlomo Eshel , Natalie Lezmy , Dan Gluck , Arnon Houri Yafin , Joseph Joel Pollak
Abstract: Apparatus and methods for analyzing a bodily sample are described. A microscope system acquires one or more microscope images of the bodily sample. A computer processor identifies, in the one or more images, at least one element as being a candidate of a given entity. The computer processor extracts, from the one or more images, at least one candidate-informative feature associated with the candidate of the given entity, and at least one sample-informative feature that is indicative of a characteristic of the bodily sample as a whole. The computer processor processes the candidate-informative feature in combination with the sample-informative feature, and generates an output upon the output device, in response thereto. Other applications are also described.
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公开(公告)号：US12181463B2
公开(公告)日：2024-12-31
申请号：US17360503
申请日：2021-06-28
Applicant: S.D. Sight Diagnostics Ltd.
Inventor： Amir Zait , Arnon Houri Yafin , Dan Gluck , Sharon Pecker , Yochay Shlomo Eshel , Sarah Levy Schreier , Joseph Joel Pollak
Abstract: Apparatus and methods are described including measuring hematocrit within a blood sample, by performing a first measurement on a first portion of the blood sample. Mean corpuscular volume in the blood sample is measured, by performing a second measurement on a second portion of the blood sample, the second portion being diluted with respect to the first portion. A red blood cell count per unit volume within the blood sample is determined by dividing the hematocrit measured within the first portion by the mean corpuscular volume measured within the second portion. Other applications are also described.
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