公开(公告)号：US20210187501A1

公开(公告)日：2021-06-24

申请号：US16071178

申请日：2017-01-31

Applicant: Scandinavian Micro Biodevices ApS

Inventor： Niels Kristian BAU-MADSEN ,  Bent OVERBY

IPC: B01L3/00 ,  B01L7/00 ,  G01N21/64

Abstract: A microfluidic assay system including a microfluidic cartridge and an associated microfluidic operator system. The microfluidic cartridge comprises a base part, having a first face with a recess and a foil fixed to the base part for covering the recess and providing a microfluidic cartridge foil face. The base part with the recess and the foil forms a flow channel and a sink in fluid communication with each other. The microfluidic cartridge comprises an inlet opening into the flow channel upstream to the reaction section.
The operator system includes a piston, a temperature regulating element and an actuator positioned such that the foil face of the microfluidic cartridge can be positioned in contact with the operative system with the reaction section in close proximity to the temperature regulating element while the actuator is associated to the sink section to depress the foil covering the sink section and the piston is associated to the flow channel at an upstream valve section to depress the foil to close off the flow channel upstream to the reaction section.

公开(公告)号：US20170203295A1

公开(公告)日：2017-07-20

申请号：US15319542

申请日：2015-06-15

Applicant: SCANDINAVIAN MICRO BIODEVICES APS

Inventor： Niels Kristian BAU-MADSEN ,  Lars Bue NIELSEN ,  Martin HELLER ,  Ole KRING ,  Olga ORDEIG ,  Bent OVERBY

IPC: B01L3/00 ,  G01N27/403 ,  G01N21/25 ,  G01N35/00 ,  G01N21/05

CPC classification number: B01L3/502715 ,  B01L9/527 ,  B01L2200/025 ,  B01L2300/02 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0864 ,  G01N21/05 ,  G01N21/25 ,  G01N21/255 ,  G01N21/31 ,  G01N21/6428 ,  G01N27/403 ,  G01N35/00029 ,  G01N35/00732 ,  G01N2021/0346 ,  G01N2021/6439 ,  G01N2035/00237 ,  G01N2035/00752 ,  G01N2035/00811 ,  G01N2035/00851 ,  G01N2201/062 ,  G01N2201/0627

Abstract: A microfluidic cartridge includes first and second sides and at least one flow channel and an inlet to the flow channel(s) for feeding a liquid sample, the flow channel(s) include a plurality of first optical detection sites. A detector assembly includes a slot for inserting the microfluidic cartridge and a first fixed light source with a beam path and an optical reader for reading out optical signals from at least one of the first optical detection site(s). When the microfluidic cartridge is inserted to a first predetermined position into the slot, one of the first optical detection sites of the microfluidic cartridge is positioned in the beam path of the first light source, and when the cartridge is inserted to a second predetermined position into the slot, another one of the first optical detection sites of the microfluidic cartridge is positioned in the beam path of the first light source.