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公开(公告)号:US20230277317A1
公开(公告)日:2023-09-07
申请号:US17931408
申请日:2022-09-12
发明人: Claudio ARGENTO , Andrew BACKUS , Alice YANG , Ali SALAHIEH , Jasper Ellington ADAMEK-BOWERS , Connor MULCAHY , Ryan William BOYD , Nicholas J. SPINELLI , Tom SAUL
IPC分类号: A61F2/24
CPC分类号: A61F2/2466 , A61F2/2457 , A61F2230/0091 , A61F2220/0008 , A61F2/82
摘要: A system for treating a diseased native valve in a patient includes a valve prosthesis and a delivery device. The prosthesis includes an anchor and a frame. The delivery device includes an outer sheath, an inner shaft, an anchor guide, and a tether. The anchor is shaped to encircle chordae or leaflets of a native valve. The frame is configured to sit within the anchor. The inner shaft is positioned within the outer sheath and translatable and rotatable relative to the outer sheath. The anchor guide is attached to a distal end of the inner shaft and has a curved distal section. The tether is configured to detachably couple to the anchor and to longitudinally translate the anchor within the inner shaft and anchor guide. The anchor is configured to be actuated from a delivery configuration to the deployed configuration when the anchor is translated out of the anchor guide.
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公开(公告)号:US20230001177A1
公开(公告)日:2023-01-05
申请号:US17784758
申请日:2020-12-11
发明人: Janine ROBINSON , Daniel HILDEBRAND , Michael CALOMENI , Veronica NEIMAN , Tom SAUL , Robert EDESESS
IPC分类号: A61M60/122 , A61M60/808
摘要: Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and/or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.
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公开(公告)号:US20220105337A1
公开(公告)日:2022-04-07
申请号:US17552311
申请日:2021-12-15
发明人: Amr SALAHIEH , Tom SAUL , Brady ESCH , Anna KERLO , Daniel HILDEBRAND , Daniel VARGHAI
IPC分类号: A61M60/135 , A61M60/414 , A61M60/148 , A61M60/205
摘要: Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.
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公开(公告)号:US20160008126A1
公开(公告)日:2016-01-14
申请号:US14860162
申请日:2015-09-21
发明人: Amr SALAHIEH , Claudio P. ARGENTO , Tom SAUL , Bob VAUGHAN , Eric WILLIS
IPC分类号: A61F2/16
摘要: An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.
摘要翻译: 用于植入患者眼睛的囊袋内的眼内透镜(IOL)包括光学结构和触觉结构。 光学结构包括平面构件,平凸构件和限定在平面构件和平凸构件之间的流体光学元件。 流体光学元件具有光学功率。 触觉结构在光学结构的周边部分处将平面构件和平凸构件连接在一起。 触觉结构包括与流体光学元件流体连通的流体储存器和用于与透镜胶囊接口的外围结构。 透镜胶囊的形状变化导致对应于平面构件中的变形的流体光学元件的体积或形状变化的一个或多个,以改变流体光学元件的光学功率。
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公开(公告)号:US20140228949A1
公开(公告)日:2014-08-14
申请号:US14181145
申请日:2014-02-14
发明人: Claudio ARGENTO , Bob VAUGHAN , Amr SALAHIEH , Tom SAUL
CPC分类号: A61F2/1648 , A61F2/1624 , A61F2/1635 , A61F2002/169 , A61F2220/005 , A61F2240/002 , B29C65/483 , B29D11/00028 , B29D11/023 , B29D11/026 , B29K2033/04 , B29K2105/0002 , B29K2995/0092 , B32B27/08 , B32B27/308 , B32B37/0076 , B32B2307/728 , B32B2333/04 , B32B2535/00
摘要: An accommodating intraocular lens comprises a first lens component, a second lens component, and an adhesive between portions of the two lens components. The cured adhesive bonds the lens components to form a fluid chamber. The lens components are bonded to one another along a seam which extends circumferentially along at least a portion of the lens components. The lens components may comprise the same polymer material. The cured adhesive also comprises the polymer or a prepolymer of the polymer to provide increased strength. The polymer is hydratable such that the lens components and the cured adhesive therebetween can swell together to inhibit stresses between the lens components and the cured adhesive.
摘要翻译: 容纳人工晶状体包括第一透镜部件,第二透镜部件和两个透镜部件的部分之间的粘合剂。 固化的粘合剂将透镜部件粘合以形成流体室。 透镜部件沿着沿透镜部件的至少一部分周向延伸的接缝彼此接合。 透镜部件可以包括相同的聚合物材料。 固化的粘合剂还包含聚合物或聚合物的预聚物以提供增强的强度。 聚合物是可水合的,使得透镜组分和它们之间的固化的粘合剂可以一起膨胀以抑制透镜部件和固化的粘合剂之间的应力。
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公开(公告)号:US20240238002A1
公开(公告)日:2024-07-18
申请号:US18562038
申请日:2022-05-19
发明人: Aadel AL-JADDA , Tom SAUL , Kevin MULLER , Amr SALAHIEH
IPC分类号: A61B17/3203 , A61B17/00 , A61B17/22
CPC分类号: A61B17/32037 , A61B17/00234 , A61B17/22 , A61B2017/00238 , A61B2017/00292 , A61B2017/22079 , A61B2217/005 , A61B2217/007
摘要: The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to at least partially fragment the thrombus, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
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公开(公告)号:US20240206892A1
公开(公告)日:2024-06-27
申请号:US18568681
申请日:2022-06-10
发明人: Aadel AL-JADDA , Tom SAUL , Kevin MULLER , Amr SALAHIEH
CPC分类号: A61B17/22 , A61B17/00234 , A61M1/87 , A61B2017/00331 , A61B2017/22079 , A61B2217/005 , A61M2210/12
摘要: The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include a fluid delivery mechanism coupled with a fluid lumen and configured to apply fluid to (1) at least partially fragment the thrombus and (2) provide an optical path for the imaging element, and an aspiration mechanism fluidly coupled to an aspiration lumen and configured to aspirate the fragmented thrombus.
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公开(公告)号:US20230363907A1
公开(公告)日:2023-11-16
申请号:US18246311
申请日:2021-09-22
发明人: Claudio ARGENTO , Andrew BACKUS , Alice YANG , Tom SAUL , Ali SALAHIEH
CPC分类号: A61F2/2442 , G06T7/0012 , G06T2207/30048
摘要: A method for treating a diseased native valve in a patient includes advancing a distal end of a delivery device that is detachable coupled to an anchor to a first side of a native valve, deploying the anchor from a delivery configuration to a deployed configuration on the first side of the native valve, advancing the anchor in the deployed configuration from the first side of the native valve to a second side of the native valve such that the anchor is located only on the second side of the native valve, rotating the anchor in the deployed configuration around chordae of the native valve, confirming a position of the anchor with an imaging source, and releasing the anchor from the distal end of the delivery device.
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公开(公告)号:US20190167407A1
公开(公告)日:2019-06-06
申请号:US16321321
申请日:2017-08-04
发明人: Alan SCHAER , Tom SAUL , Amr SALAHIEH , Lilip LAU , Don TANAKA , Sid GANDIONCO , Hung HA , Arindam DATTA
摘要: Methods of treating COPD, including bronchoscopically positioning a lung anchor in lung tissue, positioning an outer implant member in pleural space proximate the lung anchor, and coupling the lung anchor to the outer implant member and thereby compressing lung tissue.
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公开(公告)号:US20230346416A1
公开(公告)日:2023-11-02
申请号:US17905671
申请日:2021-03-04
发明人: Marwan BERRADA , Amr SALAHIEH , Tom SAUL , Aadel AL-JADDA
IPC分类号: A61B17/3203 , A61B17/3205
CPC分类号: A61B17/32037 , A61B17/32056 , A61B2017/00539
摘要: The present technology relates to systems and methods for removing a thrombus from a blood vessel of a patient. In some embodiments, the present technology is directed to systems including an elongated catheter having a distal portion configured to be positioned within the blood vessel of the patient, a proximal portion configured to be external to the patient, and a lumen extending therebetween. The system can also include an imaging element at the distal portion, an illumination source at the distal portion, a capture element at the distal portion and configured to engage the thrombus, a fluid delivery mechanism within the lumen and configured to apply fluid to (1) at least partially fragment the thrombus and (2) provide an optical path for the imaging element, and an aspiration mechanism fluidly coupled to the lumen and configured to aspirate the fragmented thrombus.
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