公开(公告)号：US20220260605A1

公开(公告)日：2022-08-18

申请号：US17628029

申请日：2019-07-26

Applicant: SHIMADZU CORPORATION

Inventor： Mika OKADA ,  Akari TAKEDA ,  Yamato MAEDA ,  Yoshitake YAMAMOTO ,  Potsun CHiANG ,  Yoshitaka NODA ,  Takashi INOUE

IPC: G01N35/10 ,  G01N35/00 ,  C12M1/00

Abstract: A cell picking device includes a stage, a sucker, a driver, a work content receiver, a registrar and a device controller. A sample container is placed on the stage. The driver is provided to execute sample scraping work and sample sucking work using a pipette tip attached to the sucker. In a case in which selection of work contents of the driver is received by the work content receiver, a work procedure including the received work contents of the driver is registered by the registrar. The work of the driver is controlled by the device controller in accordance with the registered work procedure.

公开(公告)号：US20240402208A1

公开(公告)日：2024-12-05

申请号：US18800304

申请日：2024-08-12

Applicant: SHIMADZU CORPORATION

Inventor： Mika OKADA ,  Akari TAKEDA ,  Yamato MAEDA ,  Yoshitake YAMAMOTO ,  Potsun CHIANG ,  Yoshitaka NODA ,  Takashi INOUE

IPC: G01N35/10 ,  B01L3/02 ,  B25J9/16 ,  C12M1/00 ,  C12M1/26 ,  G01N35/00

Abstract: A cell picking device includes a stage, a sucker, a driver, a work content receiver, a registrar and a device controller. A sample container is placed on the stage. The driver is provided to execute sample scraping work and sample sucking work using a pipette tip attached to the sucker. In a case in which selection of work contents of the driver is received by the work content receiver, a work procedure including the received work contents of the driver is registered by the registrar. The work of the driver is controlled by the device controller in accordance with the registered work procedure.

公开(公告)号：US20220259542A1

公开(公告)日：2022-08-18

申请号：US17628528

申请日：2019-07-26

Applicant: SHIMADZU CORPORATION

Inventor： Yamato MAEDA ,  Akari TAKEDA ,  Yoshitake YAMAMOTO ,  Yoshitaka NODA ,  Takashi INOUE

IPC: C12M1/26 ,  C12M1/00

Abstract: A cell collecting device include a pipette tip that sucks substances in a cell culture container, a first valve connected to the pipette tip through a first flow path, a first pump connected to the first valve through a second flow path, and a second pump connected to the first valve through a third flow path. In a remove mode, the first valve is switched to connect the first flow path and the second flow path to each other and disconnect the third flow path, and the first pump is driven to discharge waste in the cell culture container, that has been sucked from the pipette tip, from a drain of the first pump through the first flow path and the second flow path, and in a picking mode, the first valve is switched to connect the first flow path and the third flow path to each other and disconnect the second flow path, and the second pump is driven to suck cells in the cell culture container using the pipette tip.

公开(公告)号：US20200377833A1

公开(公告)日：2020-12-03

申请号：US16969859

申请日：2018-03-16

Applicant: SHIMADZU CORPORATION

Inventor： Takashi INOUE ,  Kenji TAKAKURA ,  Yoshitaka NODA ,  Yasuaki MATSUNAGA ,  Mika OKADA ,  Akari TAKEDA

IPC: C12M1/26 ,  B01L9/00 ,  C12M1/36

Abstract: A cell picking device includes a sucker having a pipette tip attached to a tip portion of the sucker and is used to suck the cell from a tip of the pipette tip, a driver configured to cause the sucker to perform a suction operation and move the sucker in a horizontal-plane direction and an axial direction of the pipette tip with the sucker inclined with respect to a vertical direction. A controller moves the sucker such that the tip of the pipette tip moves in a horizontal direction while being in contact with a bottom surface of the container installed on the sample mounting stage in a predetermined position on the sample mounting stage to desorb a cell arranged in the predetermined position from the bottom surface of the container, and suck the cell desorbed from the bottom surface of the container from the tip of the pipette tip.

公开(公告)号：US20220276271A1

公开(公告)日：2022-09-01

申请号：US17626841

申请日：2019-07-26

Applicant: SHIMADZU CORPORATION

Inventor： Mika OKADA ,  Akari TAKEDA

IPC: G01N35/00 ,  B01L3/02 ,  B01L9/00 ,  C12M1/32 ,  B25J15/06

Abstract: A suction arm advances in an axial direction of a pipette tip such that an end of the pipette tip comes into contact with a bottom surface of a sample container while the pipette tip attached to a suction arm is tilted with respect to a vertical direction. Next, the suction arm is moved such that the end of the pipette tip scans the bottom surface of the sample container in a horizontal direction toward a predetermined position. Subsequently, at the predetermined position, the suction arm is further tilted by a predetermined angle such that the end of the pipette tip is lifted and a base of the pipette tip is lowered. Thereafter, the suction arm performs a sucking operation such that a sample is sucked through the end of the pipette tip.

公开(公告)号：US20220268794A1

公开(公告)日：2022-08-25

申请号：US17626545

申请日：2019-07-26

Applicant: SHIMADZU CORPORATION

Inventor： Akari TAKEDA ,  Yoshitake YAMAMOTO

IPC: G01N35/00 ,  C12M1/36 ,  C12M1/26 ,  C12M1/00 ,  C12M1/34

Abstract: A cell picking device includes a supporter that supports a rack having a plurality of holes for holding a plurality of pipette tips, a sucker used to suck a sample, a driver that moves the sucker in an up-and-down direction and moves the sucker and the supporter relative to each other in a horizontal direction, and a controller that controls the driver such that, any pipette tip out of the plurality of pipette tips held by the rack is attached to the sucker by movement of the sucker in the up-and-down direction and the sucker is moved to a position outwardly of the rack by movement of the sucker and the supporter relative to each other.