公开(公告)号：US20220187332A1

公开(公告)日：2022-06-16

申请号：US17518003

申请日：2021-11-03

Applicant: SHIMADZU CORPORATION

Inventor： Naoki KANEKO ,  Ritsuko YODA ,  Akihito KORENAGA

IPC: G01N35/10 ,  H01J49/16

Abstract: In a sample pretreatment device, a container storage section (2) holds multiple containers, including a first well plate having wells in an N×M matrix form and a second well plate having N elongated wells whose length corresponds to M wells in one row of the first well plate or M elongated wells whose length corresponds to N wells in one column of the first well plate. A dispensing section (3) includes: a platform (30) on winch containers can be placed; a pipette unit (311, 312) including an M-channel tip corresponding to M wells in one row of the first well plate or an N-channel tip corresponding to N wells in one column of the first well plate; and a pump unit (313) for suctioning/ejecting a liquid from/into a container on the platform through the pipette unit. A transfer section (4) transfers containers between the container storage section and the platform. A controller (5) controls operations of the dispensing section and the transfer section.

公开(公告)号：US20230132727A1

公开(公告)日：2023-05-04

申请号：US17918648

申请日：2020-11-26

Applicant: SHIMADZU CORPORATION

Inventor： Akihito KORENAGA ,  Ritsuko YODA ,  Tatsuki OKUBO ,  Tomonori OSHIKAWA ,  Yuko KOBAYASHI ,  Yoshiki TAINAKA ,  Kohei SUZUKI

IPC: H01J49/16 ,  H01J49/00 ,  H01J49/04

Abstract: One mode of the present invention provides a laser power adjustment method for ionization in a laser desorption/ionization mass spectrometer, the laser power adjustment method including: a measurement step (S1) in which intensity information on ions derived from a specific component in a specimen are acquired while changing laser power in n stages (n is 3 or more) for the identical specimen; and a processing step (S2, S6, and S7) in which a slope of a straight line connecting two adjacent plot points on a laser power axis is calculated in a two-axis graph in which a relationship between n ionic intensities obtained by the measurement step or a signal value, which is an SN ratio obtained from the ionic intensities, and laser power is plotted; an index value reflecting a ratio between a forward slope value, which is a slope of a straight line on a front side of the plot point, and a backward slope value, which is a slope of a straight line on a rear side, is obtained for each plot point; and appropriate laser power is selected using the index value.

公开(公告)号：US20240272192A1

公开(公告)日：2024-08-15

申请号：US18438239

申请日：2024-02-09

Applicant: SHIMADZU CORPORATION

Inventor： Akihito KORENAGA ,  Hiroyuki YAMASHITA

IPC: G01N35/10

CPC classification number: G01N35/1074 ,  G01N35/1011

Abstract: A dispensing device capable of aspirating or dispensing a liquid from or into each of a plurality of wells provided on a container, the plurality of wells being aligned linearly, includes: a support portion configured to support the container; a dispensing head having a plurality of tip attachments aligned linearly, the dispensing head being configured to aspirate and dispense a liquid from or into dispensing tips attached to the tip attachments; and a first drive unit configured to rotate at least one of the dispensing head and the support portion relative to the other so that an alignment direction of the plurality of tip attachments coincides with an alignment direction of the plurality of wells.