公开(公告)号：US20170108474A1

公开(公告)日：2017-04-20

申请号：US15128310

申请日：2015-03-19

Applicant: SHOWA DENKO K.K.

Inventor： Hideyuki KONDO ,  Junji SASUGA ,  Takayuki SHUKUYA

IPC: G01N30/52 ,  B01D15/36 ,  G01N30/96 ,  G01N30/72 ,  G01N30/60

CPC classification number: G01N30/52 ,  B01D15/305 ,  B01D15/363 ,  B01D15/3847 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/6052 ,  G01N30/72 ,  G01N30/7233 ,  G01N30/88 ,  G01N30/96

Abstract: A mass spectrometry method by a liquid chromatograph-mass spectrometer that can detect an organic acid with high sensitivity by retaining, separating and eluting the organic acid without adding any nonvolatile substance to a mobile phase and without receiving any restriction of a ratio of a water-soluble organic solvent, and an analytical column are provided. The mass spectrometry method is a mass spectrometry method for an organic acid by a liquid chromatograph-mass spectrometer, wherein a column packed with a hydrophilic polymer having an anion-exchange group is used, and as a mobile phase, a water-soluble organic solvent-water mixed solution is used. The analytical column is a column for liquid chromatography for an organic acid, in which a polyether ether ketone (PEEK) resin housing for liquid chromatography is packed with a hydrophilic polymer having an anion-exchange group.