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1.发明申请公开(公告)号：US20220023208A1
公开(公告)日：2022-01-27
申请号：US17276693
申请日：2019-09-12
IPC分类号： A61K9/107 , A61K9/00 , A61K31/196 , A61K31/407 , A61K31/381 , A61K31/192 , A61K31/23
摘要： A pharmaceutical composition for topical use which is in the form of a water-in-oil emulsion including, for 100% of the weight thereof: —from 60% to 80% by weight of a gelled aqueous phase including an anti-inflammatory substance, —from 20% to 40% by weight of a fatty phase including at least one oil and an emulsifying system including a combination of at least one emulsifying surfactant selected from the elements of the group consisting of alkylpolyglycoside compositions and alkylpolyglycoside and fatty alcohol compositions, and of at least one emulsifying surfactant selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.
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公开(公告)号：US20220378672A1
公开(公告)日：2022-12-01
申请号：US17633760
申请日：2020-08-04
IPC分类号： A61K8/06 , A61Q19/04 , A61Q19/10 , A61Q19/00 , A61Q5/02 , A61K8/34 , A61K8/60 , A61K8/37 , A61K8/81
摘要： Composition for topical use including a gelled phase dispersed in a continuous phase, with: the gelled phase including a diol having 3-8 atoms and represented either by formula (Ia): Ra1-C(Rb1)(OH)—C(OH)(Rc1)(Rd1) (Ia), in which each of the Ra1, Rb1, Rc1 and Rd1 radicals represent, independently of one another, a hydrogen atom or saturated aliphatic radical having 1-5 carbon atoms, or by formula (Ib): Ra1-C(Rb1)(OH)—[C(Re1)(Rf1)]t-C(OH)(Rc1)(Rd1) (Ib), in which t is equal to one, two or three, each of the Ra1, Rb1, Rc1, Rd1, Re1 and Rf1 radicals represent, independently of one another, a hydrogen atom or saturated aliphatic radical having 1-5 carbon atoms, it being understood that at least one of the Ra1 or Rb1 radicals and/or at least one of the Rc1 or Rd1 radicals do not represent a hydrogen atom, and —a fatty phase including an oil, an emulsifying surfactant system and an emulsifying surfactant.
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公开(公告)号：US20220288022A1
公开(公告)日：2022-09-15
申请号：US17632664
申请日：2020-08-04
IPC分类号： A61K31/404 , A61K9/00 , A61K9/107 , A61K47/10 , A61K31/196 , A61K31/216 , A61K31/381 , A61K31/192 , A61K47/34
摘要： Topical pharmaceutical composition as a dispersed phase based on a short diol in a continuous fatty phase and including an anti-inflammatory substance, the composition including: a gelled phase including an anti-inflammatory substance and a diol including 3-8 carbon atoms and represented either by formula (Ia): Ra1—(Rb1)(OH)—(OH)(Rc1)(Rd1) (Ia), in which each of the radicals Ra1, Rb1, Rc1 and Rd1 represents, independently of each other, a hydrogen atom or a saturated aliphatic radical including 1-5 carbon atoms, or by formula (Ib): Ra1—C(Rb1)(OH)—[C(Re1)(Rf1)]t—C(OH)(Rc1)(Rd1) (Ib), t=1, 2 or 3, each of the radicals Ra1, Rb1, Rc1 Rd1, Re1 and Rf1 represents, independently of each other, a hydrogen atom or a saturated aliphatic radical including 1-5 carbon atoms. The radicals Ra1or Rb1 and/or the radicals Rc1or Rd1does not represent a hydrogen atom, a fatty phase including an oil and an emulsifying system including a combination of emulsifying surfactants.
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公开(公告)号：US20220193037A1
公开(公告)日：2022-06-23
申请号：US17601325
申请日：2020-04-01
IPC分类号： A61K31/4174 , A61K9/00 , A61K9/107 , A61K31/496 , A61K31/4178 , A61K47/10 , A61K47/34
摘要： Disclosed is a pharmaceutical composition for topical. use in the form of a water-in-oil emulsion including, for 100% of the weight thereof: from 0.3% to 5% by weight of at least one azolated local antifungal substance;—from 60% to 90% by weight of a gelled aqueous phase (A1);—from 9.7% to 35% by weight of a fatty phase (A2) including at least one oil and an emulsifying system including a combination of at least one emulsifying surfactant (S1) selected from the elements of the group consisting of alkylpolyglycoside compositions and alkylpolyglycoside and fatty alcohol compositions, and of at least one emulsifying surfactant (S2) selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.
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5.发明申请公开(公告)号：US20220031707A1
公开(公告)日：2022-02-03
申请号：US17276315
申请日：2019-09-12
IPC分类号： A61K31/5375 , A61K9/00 , A61K9/06 , A61K9/107 , A61K31/245 , A61K31/445 , A61K31/47 , A61K47/34
摘要： A pharmaceutical composition for topical use which is in the form of a water-in-oil emulsion including, for 100% of the weight thereof: —from 0.3% to 5% by weight of at least one local anaesthetic substance; —from 60% to 90% by weight of gelled aqueous phase; —from 9.7% to 35% by weight of a fatty phase including at least one oil and an emulsifying system including a combination of at least one emulsifying surfactant selected from the elements of the group consisting of alkylpolyglycoside compositions and alkylpolyglycoside and fatty alcohol compositions, and of at least one emulsifying surfactant selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.
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公开(公告)号：US20210386640A1
公开(公告)日：2021-12-16
申请号：US17284380
申请日：2019-10-09
摘要： Disclosed is a disinfecting composition for topical use, including a surfactant mixture based on cocoyl glutamate and alkyl polyglycosides, at least one thickening and/or gelling agent, and at least one disinfectant.
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