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公开(公告)号：US20160052950A1
公开(公告)日：2016-02-25
申请号：US14780906
申请日：2014-02-04
发明人： Andre BENATTAR , Andrey BONNARDEL , Jerome GUILBOT , Sebastien KERVERDO , Herve ROLLAND , Guy TABACCHI
CPC分类号： C07H15/04 , A61K8/602 , A61Q1/14 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/04 , A61Q19/08 , A61Q19/10 , C07D307/20 , C07D493/04 , C07H1/00
摘要： A process for preparing a composition (C1) represented by the formula (I): HO—CH2—(CHOH)n—CH2—O-(G)x-H, in which G represents the remainder of a reducing sugar, n is an integer equal to 2, 3 or 4 and x, which indicates the mean degree of polymerization of the remainder G, represents a decimal number greater than 1 and less than or equal to 5, characterized in that the process includes at least one step a) of reacting a polyol of formula (A1): HO—CH2—(CHOH)n—CH2—OH, in which n is an integer equal to 2, 3 or 4, with a reducing sugar of formula (II): HO-G-H, in which G represents the remainder of a reducing sugar, in the presence of an acid catalyst (Ca), and in that the acid catalyst (Ca) is chosen from phosphorous acid, phosphoric acid and polyphosphoric acid.
摘要翻译： 制备由式（I）表示的组合物（C1）的方法：HO-CH 2 - （CHOH）n -CH 2 -O-（G）x H，其中G表示还原糖的剩余部分，n为整数 等于2,3或4，x表示余量G的平均聚合度，表示大于1且小于或等于5的十进制数，其特征在于该方法包括至少一个步骤a） 使式（A1）的多元醇：HO-CH 2 - （CHOH）n -CH 2 -OH，其中n为等于2,3或4的整数，与式（II）的还原糖：HO-GH， 其中G代表还原糖的剩余部分，在酸催化剂（Ca）的存在下，酸催化剂（Ca）选自亚磷酸，磷酸和多磷酸。
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2.发明申请USE OF ALKYL POLYGLYCOSIDES AS PERFUME-SOLUBILISING AGENTS AND PERFUME COMPOSITION INCLUDING SAME 审中-公开使用烷基多糖作为香料溶解剂和包括其的香料组合物公开(公告)号：US20170035675A1
公开(公告)日：2017-02-09
申请号：US15105588
申请日：2014-12-03
CPC分类号： A61K8/604 , A61K2800/49 , A61Q13/00
摘要： A composition represented by the formula (I): R-0-(G)p-H, wherein R is the n-heptyl radical, G is the residue of a reducing sugar and p is a decimal number no lower than 1.05 and no higher than 5. The composition is a mixture of compounds represented by the formulas R-0-(G)1-H (I1), R-0-(G)2-H (I2), R—O-(G)3-H (I3), R—O-(G)4-H (I4), and R-0-(G)5-H (I5) in the respective molar ratios a1, a2, a3, a4 and a5, such that each ratio a1, a2, a3, a4 and a5 is between zero and one inclusive and that the sum of a1+a2+a3+a4+a5, is equal to one. Also, the method of solubilizing, in an aqueous solution, a hydrophobic perfume substance (A) or a mixture of hydrophobic perfume substances (A) with this composition, and a solubilising composition for hydrophobic perfumes. Further, a method for perfuming surfaces.
摘要翻译： 由式（I）表示的组合物：R-O-（G）pH，其中R是正庚基，G是还原糖的残基，p是小于1.05且不高于 该组合物是由式R-O-（G）1-H（I1），R-O-（G）2-H（I 2），R-O-（G）3- H（I3），R-O-（G）4-H（I4）和R-O-（G）5-H（I5）各摩尔比a1，a2，a3，a4和a5，使得 每个比率a1，a2，a3，a4和a5在0和1之间，并且a1 + a2 + a3 + a4 + a5的和等于1。 此外，在水溶液中使疏水性香料物质（A）或疏水性香料物质（A）与该组合物的混合物溶解的方法以及疏水性香料的增溶组合物。 另外，一种加香表面的方法。
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3.发明申请NOVEL USES OF ALKYL POLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER; COMPOSITIONS COMPRISING SAME 审中-公开用于溶解水中维生素E的烷基多糖的新用途; 包含相同的组合物公开(公告)号：US20160193340A1
公开(公告)日：2016-07-07
申请号：US14909336
申请日：2014-07-23
CPC分类号： A61K47/26 , A61K8/604 , A61K8/678 , A61K31/355 , A61K47/36 , A61K2800/49 , A61K2800/5922 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/10
摘要： A composition represented by formula (I): R—O-(G)p-H (I) in which R represents a radical including 6 to 8 carbon atoms, G represents the residue of a reducing sugar and p represents a decimal number greater than or equal to 1.05 and less than or equal to 5, and the composition is a mixture of compounds represented by formulae (I1), (I2), (I3), (I4) and (I5): R—O-(G)1-H(I1) R—O-(G)2-H(I2) R—O-(G)3-H(I3) R—O-(G)4-H(I4) R—O-(G)5-H(I5), in respective molar proportions a1, a2, a3, a4 and a5, such that: a1+a2+a3+a4+a5=1. The use of the composition as a solubilising agent in an aqueous composition of at least one compound (A) chosen from α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocopherol acetate, β-tocopherol acetate, γ-tocopherol acetate, δ-tocopherol acetate, α-tocotrienol, β-tocotrienol, γ-tocotrienol and δ-tocotrienol. Also, a composition (C2) and its use in methods for preventing the unattractive effects of ageing, for cleaning the skin and hair, and for therapeutic treatment.
摘要翻译： 由式（I）表示的组合物：R-O-（G）pH（I），其中R表示包含6至8个碳原子的基团，G表示还原糖的残基，p表示大于或 （I），（I 2），（I 3），（I 4）和（I 5）表示的化合物的混合物：R-O-（G）1等于1.05且小于或等于5 -H（I）R-O-（G）2-H（I 2）R-O-（G）3 -H（I 3）R-O-（G）4-H（I4）R-O- ）5-H（I5），各摩尔比例a1，a2，a3，a4和a5，使得：a1 + a2 + a3 + a4 + a5 = 1。 至少一种选自α-生育酚，生育酚，γ-生育酚，δ-生育酚，乙酸α-生育酚，醋酸生育酚，醋酸生育酚的化合物（A）的水性组合物中作为增溶剂的用途 ，γ-生育酚乙酸酯，δ-生育酚乙酸酯，α-生育三烯酚，生育三烯酚，γ-生育三烯酚和δ-生育三烯酚。 还有，组合物（C2）及其在防止老化不吸引人的作用，清洁皮肤和毛发以及进行治疗的方法中的用途。
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公开(公告)号：US20140219936A1
公开(公告)日：2014-08-07
申请号：US14222791
申请日：2014-03-24
发明人： Chantal AMALRIC , Juanshu SHEN , Jerome GUILBOT , Herve ROLLAND , Agnes GORCE , Sebastien KERVERDO
CPC分类号： A61K8/062 , A61K8/06 , A61K8/345 , A61K8/35 , A61K8/375 , A61K8/604 , A61K8/92 , A61K8/922 , A61Q5/00 , A61Q5/02 , A61Q19/00 , A61Q19/04
摘要： An oil-in-water emulsion includes, for 100 wt % thereof: a) 0.1 to 10 wt % of an emulsifying system including, for 100 wt % thereof: (i) 5 to 95 wt % of the mixture of the reaction products of a reducing sugar and 1,12-octadecanediol essentially consisting of hydroxyl-octadecyl polyglycosides of formula (I): HO—R—O-(G)n-H (I) and of polyglycosyl octadecyl polyglycosides of formula (II): H-(G)m-O—R—O-(G)p-H (II), where, in formulas (I) and (II), G is the remainder of the reducing sugar and R is the divalent radical octadecane-diyl-1,12, and where n, m and p, identical or different, each are, independently of each other, a decimal number between 1 and 5; (ii) 95 to 5 wt % of 1,12-octadecanediol; b) 0.01 to 5 wt % of at least one thickening and/or gelling agent; c) 10 to 50 wt % of an oil phase; and d) 89.89 to 35 wt % of an aqueous phase.
摘要翻译： 对于其100重量％，水包油乳液包括：a）0.1至10重量％的乳化体系，其包含100重量％的：（i）5至95重量％的反应产物的混合物 基本上由式（I）的羟基 - 十八烷基多糖苷：HO-R-O-（G）nH（I）和式（II）的多糖基十八烷基多糖苷组成的还原糖和1,12-十八烷二醇：H-（G ）mO-R-O-（G）pH（II），其中，在式（I）和（II）中，G是还原糖的剩余部分，R是二价基十八烷基 - 二基-1,12， 其中n，m和p相同或不同，各自彼此独立地为1至5之间的十进制数; （ii）95〜5重量％的1,12-十八烷二醇; b）0.01至5重量％的至少一种增稠和/或胶凝剂; c）10〜50重量％的油相; 和d）89.89〜35重量％的水相。
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